Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia - Wikidata - awgldk - TriplyDB

Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia

Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia

http://www.wikidata.org/entity/Q35791336

about

Molecular pathways: trafficking of metabolic resources in the tumor microenvironment Oncogenes induce the cancer-associated fibroblast phenotype: metabolic symbiosis and "fibroblast addiction" are new therapeutic targets for drug discovery Advances in understanding the leukaemia microenvironment How will B-cell-receptor-targeted therapies change future CLL therapy?ROS homeostasis and metabolism: a critical liaison for cancer therapy The Intercellular Metabolic Interplay between Tumor and Immune Cells CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCγ1 activation: evidence from mice and humans CD44 variant-dependent redox status regulation in liver fluke-associated cholangiocarcinoma: A target for cholangiocarcinoma treatment.Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis.New insights into redox homeostasis as a therapeutic target in B-cell malignancies.Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia.Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progression Silenced B-cell receptor response to autoantigen in a poor-prognostic subset of chronic lymphocytic leukemia.Viability and stress protection of chronic lymphoid leukemia cells involves overactivation of mitochondrial phosphoSTAT3Ser727.Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support.Famine versus feast: understanding the metabolism of tumors in vivo.MitoCeption as a new tool to assess the effects of mesenchymal stem/stromal cell mitochondria on cancer cell metabolism and function Cancer associated fibroblasts in hematological malignancies.Organometallic nucleosides induce non-classical leukemic cell death that is mitochondrial-ROS dependent and facilitated by TCL1-oncogene burden.Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells Targeted Axl Inhibition Primes Chronic Lymphocytic Leukemia B Cells to Apoptosis and Shows Synergistic/Additive Effects in Combination with BTK Inhibitors.Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells.Emerging regulatory paradigms in glutathione metabolism.Tumor-stroma relationships: who's the driver?Effective elimination of chronic lymphocytic leukemia cells in the stromal microenvironment by a novel drug combination strategy using redox-mediated mechanisms.Proteomic identification of prognostic tumour biomarkers, using chemotherapy-induced cancer-associated fibroblasts The deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function.Metabolic alterations caused by HNF1β expression in ovarian clear cell carcinoma contribute to cell survival Understanding metabolic regulation and its influence on cell physiology Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia.Metabolism pathways in chronic lymphocytic leukemia.Nutrient transporters: the Achilles' heel of anabolism.Loss of p53 in stromal fibroblasts promotes epithelial cell invasion through redox-mediated ICAM1 signal.Dynamic roles of p53-mediated metabolic activities in ROS-induced stress responses The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(-)Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer USP4 inhibits p53 and NF-κB through deubiquitinating and stabilizing HDAC2.Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche.

P2860

Q26825620-9449C96B-4744-4DD0-ACB8-D47F91920D23 Q26851813-F34259A6-52FF-4811-A5FE-E1A75B4315F2 Q26995023-D3417FC9-9A5B-499C-8C0C-8DA5B57273D3 Q27024187-55D59BDC-61C3-45DA-9903-028736C58DB1 Q28080316-0ECADB89-E63A-41C0-96D9-8EBBB52FA0C6 Q28391079-21AA2DF7-C724-4CBE-B229-A4EA0F64F3E1 Q28543785-C4536DB0-9E85-4D33-BBD6-BFFA61BCF5BA Q30378139-CE110D31-1867-42D4-A52F-A3D11578F7E8 Q33598375-B8C5F827-25E1-46D6-A1EE-9DA6A386F88A Q33629325-3FAAFA80-388D-45F3-86AD-53289CA87697 Q33797951-E28D89BF-C178-4B6E-85D7-3DDE5A32024D Q34231446-DCE5A03E-D637-4E1B-90A9-CB539D2B2874 Q34372296-9C55F057-87DF-4FD0-8BF0-BBD1847B5D5A Q34463658-E8E57931-DED4-481D-AAC7-F0E88C9F5A91 Q34541525-304B10A2-C9EF-49AB-8DDB-DB775E0840CE Q34957024-C89CC316-F95E-4A34-BC59-8AD44B98AB47 Q35122371-C9822834-9DE1-4C77-AB28-EFC407C637C1 Q35172485-2D4E2F24-9531-446E-BA16-6B164B642A1C Q35550041-E223501B-B302-4B48-A7F7-28DC400976B7 Q35676442-9B79DDCE-9E57-4424-951F-242BB9941342 Q35747414-52340E67-0462-4F21-A0DF-C34A3A91CC87 Q35775881-1CDA41EC-B2FA-4966-8A6D-86FD55946E3C Q35793591-6653A390-B25E-4AFF-9804-185AE2C6B49B Q35861964-4EA1D136-B6E9-4D43-98D5-98C6300F176D Q35891763-E49FC259-8589-4115-BB47-3FF123C51C1D Q35972810-97DE79B7-488E-4833-A4B8-85E91450B90B Q36224948-B8C2FBAB-0DB6-4974-961B-FADC1B6F198A Q36260245-77A3EF09-6FE0-4C7B-9183-76D30632BA8C Q36399027-B94A169F-AB6E-483E-A3B4-4636270B44EB Q36413347-E55F8DC3-6223-4FE1-9E09-5EAEE70EBB85 Q36602677-C77E6CA3-E995-47AE-9EEE-A43A87783A11 Q36619115-7E828E68-9C64-4A35-91B2-3D6E0F5B3A21 Q36693111-26D34ACC-02BD-4C91-9A29-8A0CF3E3CB16 Q36741646-C5CF8C1C-C5B7-4D90-84E8-139040514E0E Q36755860-FFE46097-5B1A-42E8-954C-DA2F24DB9A45 Q36780705-26E1EA31-6A9E-48C7-98BA-575E3EF0E8CA Q36917721-D1A01697-BDD7-443A-BE0F-42A4D268093A Q36922131-61939318-8609-4125-895B-D1938E272030 Q36974861-6358D47A-C69A-4F1E-9F13-298BAF0F1F02 Q37079808-4C2B9AAB-9162-4BE3-88FE-13D15975D6A3

P2860

Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia

http://www.wikidata.org/entity/Q35791336

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Stromal control of cystine met ...... chronic lymphocytic leukaemia

@ast

Stromal control of cystine met ...... chronic lymphocytic leukaemia

@en

type

label

Stromal control of cystine met ...... chronic lymphocytic leukaemia

@ast

Stromal control of cystine met ...... chronic lymphocytic leukaemia

@en

prefLabel

Stromal control of cystine met ...... chronic lymphocytic leukaemia

@ast

Stromal control of cystine met ...... chronic lymphocytic leukaemia

@en

P1433

Q35791336-0A0F71EB-DBDE-41CB-951F-209FF7BC2BBA

P1476

Q35791336-2344B774-75AC-4BD9-8A22-AF03FAC3859A

P2093

Q35791336-0EBA7BD8-D2E1-41AB-BC3D-F40D96FB6C86

Q35791336-40EB8EA1-2B3E-4DF0-8AA4-302ABE547C1A

Q35791336-41DB6CEF-2396-4CAE-8B72-15A1E6986AFA

Q35791336-4530BE15-1804-4400-B6DE-7F4F3D160D0C

Q35791336-455F2A4C-A4B8-43C2-9105-FFA88F18ED90

Q35791336-955F225E-B920-4285-8D96-37CC36E3DD05

Q35791336-9D5BAA51-DD52-495F-8AD9-C92AD621E55A

Q35791336-B0F655BF-10C2-4646-9EFF-4C0F29C6856B

Q35791336-C44E1176-F681-4938-B888-456364E8C1C9

P2860

Q35791336-01323B45-C58E-4FF5-B9FF-A87E898ADEBA

Q35791336-02919780-0A42-43A8-B498-3AB1FF655D35

Q35791336-07E7FD1F-998A-42C5-956F-EC0CF00F48FC

Q35791336-087BC771-E4D7-4975-819F-184B552DCB51

Q35791336-08FC601B-D2A3-4E42-93A8-41C5A51170F5

Q35791336-1B53F19F-C120-4AE2-B9C2-711466D5A526

Q35791336-209C7DBB-C33C-44B7-B195-B0842972D88B

Q35791336-2DC54377-6881-4820-885E-727DE0737EF2

Q35791336-35305280-67F2-446B-A4D7-22153DB1BD36

Q35791336-3ABDB572-D187-4A76-B608-DE17E4317F1C

P2888

Q35791336-FD04F291-D608-4EAD-A158-D39BECE4C19C

P304

Q35791336-5BE77A75-C4AB-467B-AE22-777FF8A365CF

P31

Q35791336-BD4A4C15-FCDE-45B9-9DFE-1560547E662A

P356

Q35791336-A0BE81DC-4AB7-4FBB-8080-CCCC804A20D9

P433

Q35791336-E91C2684-DFFA-427A-A060-423060DAF346

P478

Q35791336-B9F8CA42-9840-4A70-8364-F9AA28A4F0B8

P50

Q35791336-615BFE0B-3FC9-43C4-80D3-FEAF8DB10E52

Q35791336-689617AD-1B93-412E-B8B4-64E46639366D

Q35791336-EFB02710-C058-4A00-8334-F601743F2F64

P577

Q35791336-5B9FACF6-CA9E-485F-B5E2-859C555B7BB7

P5875

Q35791336-EDCBB61C-C1B9-44CA-A98B-9CEC0D641255

P698

Q35791336-0CC1E86B-9C9B-46E6-BB6F-F4B6C7D97D9A

P921

Q35791336-37525FE5-3889-44E0-B8F0-AD8E107CBA9B

Q35791336-BE305275-4BF9-4300-8788-B325972856F6

P932

Q35791336-3E315F4D-EAA6-449B-A53B-0CDEA87CF43C

P356

P1433

Nature Cell Biology

P1476

Stromal control of cystine met ...... chronic lymphocytic leukaemia

@en

P2093

Celia Garcia-Prieto

http://www.w3.org/2001/XMLSchema#string

Dunyaporn Trachootham

http://www.w3.org/2001/XMLSchema#string

Gang Chen

http://www.w3.org/2001/XMLSchema#string

Helene Pelicano

http://www.w3.org/2001/XMLSchema#string

Jan A Burger

http://www.w3.org/2001/XMLSchema#string

Jinyun Liu

http://www.w3.org/2001/XMLSchema#string

Peng Huang

http://www.w3.org/2001/XMLSchema#string

Wan Zhang

http://www.w3.org/2001/XMLSchema#string

Weiqin Lu

http://www.w3.org/2001/XMLSchema#string

P2860

Glutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosis

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

Regulation of glutathione synthesis

Chronic lymphocytic leukemia

Clinical pharmacokinetics of oxaliplatin: a critical review.

Regulation of glutathione synthesis.

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

Biology of chronic lymphocytic leukemia.

Redox imbalance in cystine/glutamate transporter-deficient mice.

The resurgence of platinum-based cancer chemotherapy.

P2888

P304

276-286

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NCB2432

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

14

http://www.w3.org/2001/XMLSchema#string

P50

Carlo Maria Croce

Michael J. Keating

William Plunkett

P577

2012-02-19T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

221841543

http://www.w3.org/2001/XMLSchema#string

P698

22344033

http://www.w3.org/2001/XMLSchema#string

P921

P932

3290742

http://www.w3.org/2001/XMLSchema#string