Transgenic overexpression of platelet-derived growth factor-C in the mouse heart induces cardiac fibrosis, hypertrophy, and dilated cardiomyopathy
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Current Insights into Molecular Mechanisms of Alzheimer Disease and Their Implications for Therapeutic ApproachesPlatelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinomaTransient receptor potential (TRP) channels and cardiac fibrosisInactivation of Smad5 in endothelial cells and smooth muscle cells demonstrates that Smad5 is required for cardiac homeostasisPharmacological targeting of the PDGF-CC signaling pathway for blood-brain barrier restoration in neurological disordersRole of platelet-derived growth factors in physiology and medicineActivation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke.Molecular Signals Elicited by GPCR Agonists in Hypertension, Cardiovascular Remodeling: Are MMPs and ADAMs Elusive Therapeutic Targets?Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers.Targeting the PDGF signaling pathway in the treatment of non-malignant diseases.Structural requirements for activation of latent platelet-derived growth factor CC by tissue plasminogen activator.Gender influences cardiac function in the mdx model of Duchenne cardiomyopathy.Cardiac progenitor cell cycling stimulated by pim-1 kinaseMurine left atrium and left atrial appendage structure and function: echocardiographic and morphologic evaluationPDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticityDnmt3a Regulates Proliferation of Muscle Satellite Cells via p57Kip2.Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart.I-Wire Heart-on-a-Chip I: Three-dimensional cardiac tissue constructs for physiology and pharmacology.Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family.Imatinib attenuates cardiac fibrosis by inhibiting platelet-derived growth factor receptors activation in isoproterenol induced model.Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis.The role of PDGF in radiation oncology.Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts.100-fold but not 50-fold dystrophin overexpression aggravates electrocardiographic defects in the mdx model of Duchenne muscular dystrophy.Extracellular matrix alterations in the atria: insights into the mechanisms and perpetuation of atrial fibrillation.Involvement of PDGF in fibrosis and scleroderma: recent insights from animal models and potential therapeutic opportunitiesRegulatory RNAs and paracrine networks in the heart.Platelet-derived growth factor signaling in the lung. From lung development and disease to clinical studies.Cellular Interplay between Cardiomyocytes and Nonmyocytes in Cardiac Remodeling.PDGF-C is a proinflammatory cytokine that mediates renal interstitial fibrosis.Development of wound healing models to study TGFβ3's effect on SMA.High glucose induces platelet-derived growth factor-C via carbohydrate response element-binding protein in glomerular mesangial cells.Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors.The Processes and Mechanisms of Cardiac and Pulmonary Fibrosis.Angiotensin II induction of PDGF-C expression is mediated by AT1 receptor-dependent Egr-1 transactivation.Enhanced heart failure, mortality and renin activation in female mice with experimental dilated cardiomyopathy.Involvement of platelet-derived growth factor ligands and receptors in tumorigenesis.PDGF-C and -D and their receptors PDGFR-alpha and PDGFR-beta in atherosclerotic human arteries.Platelet-derived growth factor is involved in the differentiation of second heart field-derived cardiac structures in chicken embryos.Over-expression of PDGF-C using a lung specific promoter results in abnormal lung development.
P2860
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P2860
Transgenic overexpression of platelet-derived growth factor-C in the mouse heart induces cardiac fibrosis, hypertrophy, and dilated cardiomyopathy
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Transgenic overexpression of p ...... hy, and dilated cardiomyopathy
@ast
Transgenic overexpression of p ...... hy, and dilated cardiomyopathy
@en
type
label
Transgenic overexpression of p ...... hy, and dilated cardiomyopathy
@ast
Transgenic overexpression of p ...... hy, and dilated cardiomyopathy
@en
prefLabel
Transgenic overexpression of p ...... hy, and dilated cardiomyopathy
@ast
Transgenic overexpression of p ...... hy, and dilated cardiomyopathy
@en
P2093
P2860
P1476
Transgenic overexpression of p ...... hy, and dilated cardiomyopathy
@en
P2093
Annica Pontén
Arne Ostman
Karin Aase
Peter Thorén
Tobias Sjöblom
Ulf Eriksson
P2860
P304
P356
10.1016/S0002-9440(10)63694-2
P407
P577
2003-08-01T00:00:00Z