Ten novel mutations in the erythroid transcription factor KLF1 gene associated with increased fetal hemoglobin levels in adults.
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Compound heterozygosity for KLF1 mutations is associated with microcytic hypochromic anemia and increased fetal hemoglobinKrüppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variantsKLF1 mutations are relatively more common in a thalassemia endemic region and ameliorate the severity of β-thalassemiaFetal hemoglobin in sickle cell anemia: genetic studies of the Arab-Indian haplotypeErythropoiesis: development and differentiation.2p15-p16.1 microdeletions encompassing and proximal to BCL11A are associated with elevated HbF in addition to neurologic impairmentThe switch from fetal to adult hemoglobinCell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell diseaseOriginal Research: Stable expression of miR-34a mediates fetal hemoglobin induction in K562 cells.A novel 33-Gene targeted resequencing panel provides accurate, clinical-grade diagnosis and improves patient management for rare inherited anaemiasEKLF/KLF1, a tissue-restricted integrator of transcriptional control, chromatin remodeling, and lineage determination.Interpreting elevated fetal hemoglobin in pathology and health at the basic laboratory level: new and known γ- gene mutations associated with hereditary persistence of fetal hemoglobin.Krüppel-like factor 1: hematologic phenotypes associated with KLF1 gene mutations.HbA2 : biology, clinical relevance and a possible target for ameliorating sickle cell disease.Molecular Characterization of β-Thalassemia in the Czech and Slovak Populations: Mediterranean, Asian and Unique Mutations.Pharmacogenomics of sickle cell disease: steps toward personalized medicine.Using the hemoglobin switch for the treatment of sickle cell disease.Polymorphism in the HMOX1 gene is associated with high levels of fetal hemoglobin in Brazilian patients with sickle cell anemia.A novel 519_525dup mutation of KLF1 gene identified in a Chinese blood donor with Lu(a-b-) phenotype.Transcription factors Fli1 and EKLF in the differentiation of megakaryocytic and erythroid progenitor in 5q- syndrome and in Diamond-Blackfan anemia.A single nucleotide polymorphism in the HBBP1 gene in the human β-globin locus is associated with a mild β-thalassemia disease phenotype.KLF1 gene mutations in Chinese adults with increased fetal hemoglobin.Synergistic effect of two β globin gene cluster mutations leading to the hereditary persistence of fetal hemoglobin (HPFH) phenotype.Changes in hematological parameters in α-thalassemia individuals co-inherited with erythroid Krüppel-like factor mutations.Molecular analysis of the rare in(Lu) blood type: toward decoding the phenotypic outcome of haploinsufficiency for the transcription factor KLF1.Utility of the multivariate approach in predicting β-thalassemia intermedia or β-thalassemia major types In Iranian patients.Mutation screening of the Krüppel-like factor 1 gene using single-strand conformational polymorphism in a cohort of Iranian β-thalassemia patients.Does the Novel KLF1 Gene Mutation Lead to a Delay in Fetal Hemoglobin Switch?Functional analysis of a novel KLF1 gene promoter variation associated with hereditary persistence of fetal hemoglobin.A common molecular signature of patients with sickle cell disease revealed by microarray meta-analysis and a genome-wide association studyKLF10gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in β-hemoglobinopathy patients
P2860
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P2860
Ten novel mutations in the erythroid transcription factor KLF1 gene associated with increased fetal hemoglobin levels in adults.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Ten novel mutations in the ery ...... l hemoglobin levels in adults.
@ast
Ten novel mutations in the ery ...... l hemoglobin levels in adults.
@en
type
label
Ten novel mutations in the ery ...... l hemoglobin levels in adults.
@ast
Ten novel mutations in the ery ...... l hemoglobin levels in adults.
@en
prefLabel
Ten novel mutations in the ery ...... l hemoglobin levels in adults.
@ast
Ten novel mutations in the ery ...... l hemoglobin levels in adults.
@en
P2093
P2860
P1433
P1476
Ten novel mutations in the ery ...... l hemoglobin levels in adults.
@en
P2093
Alice E Gallienne
Anna Schuh
Hélène M P Dréau
John M Old
Shirley Henderson
P2860
P304
P356
10.3324/HAEMATOL.2011.055442
P577
2011-11-18T00:00:00Z