Allosteric modulation of Ca2+ flux in ligand-gated cation channel (P2X4) by actions on lateral portals
about
Insights into the channel gating of P2X receptors from structures, dynamics and small moleculesP2X4 receptors (P2X4Rs) represent a novel target for the development of drugs to prevent and/or treat alcohol use disordersPrinciples and properties of ion flow in P2X receptorsImaging P2X4 receptor subcellular distribution, trafficking, and regulation using P2X4-pHluorinP2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology.Neuromodulation by extracellular ATP and P2X receptors in the CNS.Multiple roles of the extracellular vestibule amino acid residues in the function of the rat P2X4 receptor.Quantifying Ca2+ current and permeability in ATP-gated P2X7 receptors.Roles of the lateral fenestration residues of the P2X₄ receptor that contribute to the channel function and the deactivation effect of ivermectinImaging P2X4 receptor lateral mobility in microglia: regulation by calcium and p38 MAPK.The spatial structure of cell signaling systems.P2X receptors as drug targets.Unanticipated parallels in architecture and mechanism between ATP-gated P2X receptors and acid sensing ion channels.Key sites for P2X receptor function and multimerization: overview of mutagenesis studies on a structural basis.Tryptophan 46 is a site for ethanol and ivermectin action in P2X4 receptors.Ivermectin and its target molecules: shared and unique modulation mechanisms of ion channels and receptors by ivermectin.P2X4 Receptor in Silico and Electrophysiological Approaches Reveal Insights of Ivermectin and Zinc Allosteric Modulation.The Molecular Determinants of Small-Molecule Ligand Binding at P2X Receptors.
P2860
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P2860
Allosteric modulation of Ca2+ flux in ligand-gated cation channel (P2X4) by actions on lateral portals
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Allosteric modulation of Ca2+ ...... by actions on lateral portals
@ast
Allosteric modulation of Ca2+ ...... by actions on lateral portals
@en
type
label
Allosteric modulation of Ca2+ ...... by actions on lateral portals
@ast
Allosteric modulation of Ca2+ ...... by actions on lateral portals
@en
prefLabel
Allosteric modulation of Ca2+ ...... by actions on lateral portals
@ast
Allosteric modulation of Ca2+ ...... by actions on lateral portals
@en
P2093
P2860
P356
P1476
Allosteric modulation of Ca2+ ...... by actions on lateral portals
@en
P2093
Baljit S Khakh
Damien S K Samways
Terrance M Egan
P2860
P304
P356
10.1074/JBC.M111.322461
P407
P577
2012-01-04T00:00:00Z