Gated access to the pore of a P2X receptor: structural implications for closed-open transitions.
about
Molecular and functional properties of P2X receptors--recent progress and persisting challengesIon access pathway to the transmembrane pore in P2X receptor channelsInsights into the channel gating of P2X receptors from structures, dynamics and small moleculesSize matters in activation/inhibition of ligand-gated ion channelsPrinciples and properties of ion flow in P2X receptorsMolecular mechanism of ATP binding and ion channel activation in P2X receptorsA dual polybasic motif determines phosphoinositide binding and regulation in the P2X channel familyConductance of P2X4 purinergic receptor is determined by conformational equilibrium in the transmembrane regionLocalization of the gate and selectivity filter of the full-length P2X7 receptorTightening of the ATP-binding sites induces the opening of P2X receptor channelsPurinergic control of inflammation and thrombosis: Role of P2X1 receptorsNeuromodulation by extracellular ATP and P2X receptors in the CNS.Pore-opening mechanism in trimeric P2X receptor channelsAminoglycoside block of P2X2 receptors heterologously expressed in Xenopus laevis oocytes.Structural insights into the function of P2X4: an ATP-gated cation channel of neuroendocrine cells.Multiple roles of the extracellular vestibule amino acid residues in the function of the rat P2X4 receptor.The second transmembrane domain of P2X7 contributes to dilated pore formationFunctional identification of close proximity amino acid side chains within the transmembrane-spanning helixes of the P2X2 receptorAgonist trapped in ATP-binding sites of the P2X2 receptor.Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors).Roles of the lateral fenestration residues of the P2X₄ receptor that contribute to the channel function and the deactivation effect of ivermectinAllosteric modulation of Ca2+ flux in ligand-gated cation channel (P2X4) by actions on lateral portalsGating mechanism of a P2X4 receptor developed from normal mode analysis and molecular dynamics simulationsWhole Genome Pathway Analysis Identifies an Association of Cadmium Response Gene Loss with Copy Number Variation in Mutant p53 Bearing Uterine Endometrial Carcinomas.Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channelInter- and intrasubunit interactions between transmembrane helices in the open state of P2X receptor channels.Structural and functional properties of the rat P2X4 purinoreceptor extracellular vestibule during gating.Structural and molecular modeling features of P2X receptors.New structure enlivens interest in P2X receptors.Post-translational regulation of P2X receptor channels: modulation by phospholipidsKey sites for P2X receptor function and multimerization: overview of mutagenesis studies on a structural basis.P2X Receptor Activation.Highly conserved tyrosine 37 stabilizes desensitized states and restricts calcium permeability of ATP-gated P2X3 receptor.The intracellular amino terminus plays a dominant role in desensitization of ATP-gated P2X receptor ion channels.P2X receptor channels show threefold symmetry in ionic charge selectivity and unitary conductance.Intermediate closed channel state(s) precede(s) activation in the ATP-gated P2X2 receptor.
P2860
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P2860
Gated access to the pore of a P2X receptor: structural implications for closed-open transitions.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Gated access to the pore of a ...... s for closed-open transitions.
@ast
Gated access to the pore of a ...... s for closed-open transitions.
@en
type
label
Gated access to the pore of a ...... s for closed-open transitions.
@ast
Gated access to the pore of a ...... s for closed-open transitions.
@en
prefLabel
Gated access to the pore of a ...... s for closed-open transitions.
@ast
Gated access to the pore of a ...... s for closed-open transitions.
@en
P2093
P2860
P356
P1476
Gated access to the pore of a ...... ns for closed-open transitions
@en
P2093
Baljit S Khakh
Jeff Abramson
Sebastian Kracun
P2860
P304
10110-10121
P356
10.1074/JBC.M109.089185
P407
P577
2010-01-21T00:00:00Z