LRIG1 modulates cancer cell sensitivity to Smac mimetics by regulating TNFα expression and receptor tyrosine kinase signaling

LRIG1 modulates cancer cell sensitivity to Smac mimetics by regulating TNFα expression and receptor tyrosine kinase signaling

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http://www.wikidata.org/entity/Q35803259
Small-molecule SMAC mimetics as new cancer therapeuticsBM-1197: a novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivoThe LRIG family: enigmatic regulators of growth factor receptor signaling.LCL161 increases paclitaxel-induced apoptosis by degrading cIAP1 and cIAP2 in NSCLC.LRIG and cancer prognosis.LRIG1 enhances the radiosensitivity of radioresistant human glioblastoma U251 cells via attenuation of the EGFR/Akt signaling pathway.USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics.Targeting inhibitors of apoptosis proteins (IAPs) for new breast cancer therapeuticsLRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells.Identification of DR5 as a critical, NF-κB-regulated mediator of Smac-induced apoptosis.PKC activation sensitizes basal-like breast cancer cell lines to Smac mimetics.Downregulation of LRIG2 expression inhibits angiogenesis of glioma via EGFR/VEGF-A pathway.Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis.Downregulation of leucine-rich repeats and immunoglobulin-like domains 1 by microRNA-20a modulates gastric cancer multidrug resistance.Derivatization of inhibitor of apoptosis protein (IAP) ligands yields improved inducers of estrogen receptor α degradation.
P2860

LRIG1 modulates cancer cell sensitivity to Smac mimetics by regulating TNFα expression and receptor tyrosine kinase signaling

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http://www.wikidata.org/entity/Q35803259
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2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
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name
LRIG1 modulates cancer cell se ...... ptor tyrosine kinase signaling
@ast
LRIG1 modulates cancer cell se ...... ptor tyrosine kinase signaling
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type
label
LRIG1 modulates cancer cell se ...... ptor tyrosine kinase signaling
@ast
LRIG1 modulates cancer cell se ...... ptor tyrosine kinase signaling
@en
prefLabel
LRIG1 modulates cancer cell se ...... ptor tyrosine kinase signaling
@ast
LRIG1 modulates cancer cell se ...... ptor tyrosine kinase signaling
@en
P1433
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P2860
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LRIG1 modulates cancer cell se ...... ptor tyrosine kinase signaling
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P2093
P2860
P304
P31
P356
10.1158/0008-5472.CAN-11-2428
P407
P433
P478
P577
P5875
P698
P932