Selective targeting of the LIGHT-HVEM costimulatory system for the treatment of graft-versus-host disease.
about
Autoimmune therapies targeting costimulation and emerging trends in multivalent therapeuticsThe Role of Animal Models in the Study of Hematopoietic Stem Cell Transplantation and GvHD: A Historical OverviewFully recombinant IgG2a Fc multimers (stradomers) effectively treat collagen-induced arthritis and prevent idiopathic thrombocytopenic purpura in miceLIGHT induces distinct signals to clear an AAV-expressed persistent antigen in the mouse liver and to induce liver inflammation.Herpes virus entry mediator (HVEM) modulates proliferation and activation of regulatory T cells following HSV-1 infectionTargeting of B and T lymphocyte associated (BTLA) prevents graft-versus-host disease without global immunosuppression.Dichotomous regulation of GVHD through bidirectional functions of the BTLA-HVEM pathway.HDAC inhibition and graft versus host diseaseHerpesvirus entry mediator (TNFRSF14) regulates the persistence of T helper memory cell populations.Cell surface signaling molecules in the control of immune responses: a tide model.Herpesvirus entry mediator regulates hypoxia-inducible factor-1α and erythropoiesis in mice.The signaling networks of the herpesvirus entry mediator (TNFRSF14) in immune regulationPathogenesis of acute graft-versus-host disease: from intestinal microbiota alterations to donor T cell activation.Pathophysiology of acute graft-versus-host disease: recent advances.Immunoregulation by tumor necrosis factor superfamily member LIGHTA crucial role for HVEM and BTLA in preventing intestinal inflammationTherapeutic blockade of LIGHT interaction with herpesvirus entry mediator and lymphotoxin β receptor attenuates in vivo cytotoxic allogeneic responsesThe TNF Receptor Superfamily in Co-stimulating and Co-inhibitory ResponsesTargeting deacetylases to improve outcomes after allogeneic bone marrow transplantation.Targeting lymphocyte activation through the lymphotoxin and LIGHT pathwaysEctopic lymphoid tissues and local immunity.Expression of anti-HVEM single-chain antibody on tumor cells induces tumor-specific immunity with long-term memory.Immunotherapeutic targeting of LIGHT/LTβR/HVEM pathway fully recapitulates the reduced cytotoxic phenotype of LIGHT-deficient T cells.Immunosuppressive effect of bone marrow-derived mesenchymal stem cells in inflammatory microenvironment favours the growth of B16 melanoma cells.Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partnersSelective blockade of herpesvirus entry mediator-B and T lymphocyte attenuator pathway ameliorates acute graft-versus-host reaction.New perspectives on the biology of acute GVHD.HVEM/LIGHT/BTLA/CD160 cosignaling pathways as targets for immune regulation.GVHD prevention: an ounce is better than a pound.LIGHT/HVEM/LTβR interaction as a target for the modulation of the allogeneic immune response in transplantation.Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease.T-cell costimulatory molecules in acute-graft-versus host disease: therapeutic implications.Herpesvirus Entry Mediator and Ocular Herpesvirus Infection: More than Meets the Eye.Pathogenic Function of Herpesvirus Entry Mediator in Experimental Autoimmune Uveitis by Induction of Th1- and Th17-Type T Cell Responses.
P2860
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P2860
Selective targeting of the LIGHT-HVEM costimulatory system for the treatment of graft-versus-host disease.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Selective targeting of the LIG ...... of graft-versus-host disease.
@ast
Selective targeting of the LIG ...... of graft-versus-host disease.
@en
type
label
Selective targeting of the LIG ...... of graft-versus-host disease.
@ast
Selective targeting of the LIG ...... of graft-versus-host disease.
@en
prefLabel
Selective targeting of the LIG ...... of graft-versus-host disease.
@ast
Selective targeting of the LIG ...... of graft-versus-host disease.
@en
P2093
P2860
P1433
P1476
Selective targeting of the LIG ...... t of graft-versus-host disease
@en
P2093
Andrew S Flies
Dallas B Flies
Gefeng Zhu
Haiying Xu
Koji Tamada
Lieping Chen
Robert A Anders
Sarah J Flies
Wayne W Hancock
P2860
P304
P356
10.1182/BLOOD-2006-09-047332
P407
P577
2006-12-19T00:00:00Z