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Effects of simulated altitude (normobaric hypoxia) on cardiorespiratory parameters and circulating endothelial precursors in healthy subjectsHypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein responseInactivation of the CYLD deubiquitinase by HPV E6 mediates hypoxia-induced NF-kappaB activationHypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cellsThe pancreas cancer microenvironmentDifferential impact of EGFR-targeted therapies on hypoxia responses: implications for treatment sensitivity in triple-negative metastatic breast cancerBeneficial compaction of spinal cord lesion by migrating astrocytes through glycogen synthase kinase-3 inhibition.Insulin-like growth factor-binding protein-1 (IGFBP-1) mediates hypoxia-induced embryonic growth and developmental retardation.Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth.Necrosis related HIF-1alpha expression predicts prognosis in patients with endometrioid endometrial carcinoma.Hypoxia-inducible factor-1 as a therapeutic target in endometrial cancer managementTargeting of albumin-embedded paclitaxel nanoparticles to tumors.Clinical biomarkers for hypoxia targeting1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine: an anticancer agent targeting hypoxic cells.Antiangiogenic activity of phthalides-enriched Angelica Sinensis extract by suppressing WSB-1/pVHL/HIF-1α/VEGF signaling in bladder cancer.Reductive activation of the prodrug 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine (KS119) selectively occurs in oxygen-deficient cells and overcomes O(6)-alkylguanine-DNA alkyltransferase mediated KS119 tumMolecular pathogenesis of bone metastases in breast cancer: Proven and emerging therapeutic targetsPim-1 knockdown potentiates paclitaxel-induced apoptosis in human hormone-refractory prostate cancers through inhibition of NHEJ DNA repair.VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migrationThe ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer.KS900: A hypoxia-directed, reductively activated methylating antitumor prodrug that selectively ablates O(6)-alkylguanine-DNA alkyltransferase in neoplastic cells.Hypoxia and radiation therapy: past history, ongoing research, and future promise.Homing of cancer cells to the boneLow oxygen levels induce the expression of the embryonic morphogen Nodal.Elevated mRNA expression of CHAC1 splicing variants is associated with poor outcome for breast and ovarian cancer patientsPrognostic and predictive significance of plasma HGF and IL-8 in a phase III trial of chemoradiation with or without tirapazamine in locoregionally advanced head and neck cancer.Low Molecular Weight Fucoidan Inhibits Tumor Angiogenesis through Downregulation of HIF-1/VEGF Signaling under Hypoxia.Dexamethasone inhibits hypoxia-induced epithelial-mesenchymal transition in colon cancerSelection, Analysis and Improvement of Anti-Angiogenesis Compounds Identified by an Anti-HIF-1α Screening and Validation System.High Expression of Derlin-1 Is Associated with the Malignancy of Bladder Cancer in a Chinese Han Population.MicroRNAs in the imprinted DLK1-DIO3 region repress the epithelial-to-mesenchymal transition by targeting the TWIST1 protein signaling networkHIF-1alpha regulates epithelial inflammation by cell autonomous NFkappaB activation and paracrine stromal remodelingPrognostic Relevance of the Expression of CA IX, GLUT-1, and VEGF in Ovarian Epithelial Cancers.Derlin-1 is overexpressed in human breast carcinoma and protects cancer cells from endoplasmic reticulum stress-induced apoptosis.Effects of hypoxia on heterotypic macrophage interactions.Methylalpinumisoflavone inhibits hypoxia-inducible factor-1 (HIF-1) activation by simultaneously targeting multiple pathwaysThree-dimensional context regulation of metastasis.Generation of oxygen deficiency in cell culture using a two-enzyme system to evaluate agents targeting hypoxic tumor cells.Phase II study of tirapazamine, cisplatin, and etoposide and concurrent thoracic radiotherapy for limited-stage small-cell lung cancer: SWOG 0222.Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Hypoxic gene expression and metastasis.
@ast
Hypoxic gene expression and metastasis.
@en
type
label
Hypoxic gene expression and metastasis.
@ast
Hypoxic gene expression and metastasis.
@en
prefLabel
Hypoxic gene expression and metastasis.
@ast
Hypoxic gene expression and metastasis.
@en
P2093
P1476
Hypoxic gene expression and metastasis.
@en
P2093
Amato J Giaccia
Nicholas C Denko
Quynh-Thu Le
P304
P356
10.1023/B:CANC.0000031768.89246.D7
P577
2004-08-01T00:00:00Z
P6179
1007417422