Safe and sustained vaginal delivery of pyrimidinedione HIV-1 inhibitors from polyurethane intravaginal rings
about
Engineering a segmented dual-reservoir polyurethane intravaginal ring for simultaneous prevention of HIV transmission and unwanted pregnancyPharmacokinetic evaluation of tenofovir disoproxil fumarate released from an intravaginal ring in pigtailed macaques after 6 months of continuous use.An intravaginal ring that releases the NNRTI MIV-150 reduces SHIV transmission in macaquesMicrobicides for the Treatment of Sexually Transmitted HIV Infections.A perspective on progress and gaps in HIV prevention scienceSafety and pharmacokinetics of intravaginal rings delivering tenofovir in pig-tailed macaques.A 90-day tenofovir reservoir intravaginal ring for mucosal HIV prophylaxis.Partial protection against multiple RT-SHIV162P3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220.Pharmacokinetics and efficacy of a vaginally administered maraviroc gel in rhesus macaquesPharmacokinetic and Pharmacodynamic Evaluation following Vaginal Application of IQB3002, a Dual-Chamber Microbicide Gel Containing the Nonnucleoside Reverse Transcriptase Inhibitor IQP-0528 in Rhesus Macaques.Controlling the hydration rate of a hydrophilic matrix in the core of an intravaginal ring determines antiretroviral releaseAn Intravaginal Ring for the Simultaneous Delivery of an HIV-1 Maturation Inhibitor and Reverse-Transcriptase Inhibitor for Prophylaxis of HIV TransmissionAnimal models for microbicide safety and efficacy testing.Safety and Pharmacokinetics of Quick-Dissolving Polymeric Vaginal Films Delivering the Antiretroviral IQP-0528 for Preexposure Prophylaxis.Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges.Novel preclinical models of topical PrEP pharmacodynamics provide rationale for combination of drugs with complementary propertiesOsmotic pump tablets for delivery of antiretrovirals to the vaginal mucosa.Pharmacokinetic and safety analyses of tenofovir and tenofovir-emtricitabine vaginal tablets in pigtailed macaques.Evaluation of poly(lactic-co-glycolic acid) and poly(dl-lactide-co-ε-caprolactone) electrospun fibers for the treatment of HSV-2 infection.Repeated administration of high-dose depot medroxyprogesterone acetate does not alter SHIVSF162p3 viral kinetics and tenofovir pharmacokinetics when delivered via intravaginal rings.A Dose Ranging Pharmacokinetic Evaluation of IQP-0528 Released from Intravaginal Rings in Non-Human Primates.
P2860
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P2860
Safe and sustained vaginal delivery of pyrimidinedione HIV-1 inhibitors from polyurethane intravaginal rings
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Safe and sustained vaginal del ...... olyurethane intravaginal rings
@ast
Safe and sustained vaginal del ...... olyurethane intravaginal rings
@en
type
label
Safe and sustained vaginal del ...... olyurethane intravaginal rings
@ast
Safe and sustained vaginal del ...... olyurethane intravaginal rings
@en
prefLabel
Safe and sustained vaginal del ...... olyurethane intravaginal rings
@ast
Safe and sustained vaginal del ...... olyurethane intravaginal rings
@en
P2093
P2860
P356
P1476
Safe and sustained vaginal del ...... olyurethane intravaginal rings
@en
P2093
Amy Martin
Chou-Pong Pau
James Smith
Janet McNicholl
Karen Watson-Buckheit
Lorna Rabe
Priya Srinivasan
R Michael Hendry
Robert Buckheit
P2860
P304
P356
10.1128/AAC.05721-11
P407
P577
2011-12-12T00:00:00Z