Rationally designed small molecules that target both the DNA and RNA causing myotonic dystrophy type 1.

Rationally designed small molecules that target both the DNA and RNA causing myotonic dystrophy type 1.

Item
http://www.wikidata.org/entity/Q35810024
A journey in bioinspired supramolecular chemistry: from molecular tweezers to small molecules that target myotonic dystrophySmall Molecule-Based Pattern Recognition To Classify RNA Structure.Cyclic mismatch binding ligand CMBL4 binds to the 5'-T-3'/5'-GG-3' site by inducing the flipping out of thymine base.A Potent Inhibitor of Protein Sequestration by Expanded Triplet (CUG) Repeats that Shows Phenotypic Improvements in a Drosophila Model of Myotonic Dystrophy.Drosophila melanogaster As a Model Organism to Study RNA Toxicity of Repeat Expansion-Associated Neurodegenerative and Neuromuscular DiseasesThe Emerging Role of RNA as a Therapeutic Target for Small Molecules.Faulty RNA splicing: consequences and therapeutic opportunities in brain and muscle disorders.RNA biology of disease-associated microsatellite repeat expansions.Design of a "Mini" Nucleic Acid Probe for Cooperative Binding of an RNA-Repeated Transcript Associated with Myotonic Dystrophy Type 1.Selective alkylation of T-T mismatched DNA using vinyldiaminotriazine-acridine conjugate.Design of Bivalent Nucleic Acid Ligands for Recognition of RNA-Repeated Expansion Associated with Huntington's Disease.Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR.Insights into the development of chemical probes for RNA
P2860

Rationally designed small molecules that target both the DNA and RNA causing myotonic dystrophy type 1.

Item
http://www.wikidata.org/entity/Q35810024
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
@zh-mo
2015年論文
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2015年论文
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2015年论文
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2015年论文
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name
Rationally designed small mole ...... ing myotonic dystrophy type 1.
@ast
Rationally designed small mole ...... ing myotonic dystrophy type 1.
@en
type
label
Rationally designed small mole ...... ing myotonic dystrophy type 1.
@ast
Rationally designed small mole ...... ing myotonic dystrophy type 1.
@en
prefLabel
Rationally designed small mole ...... ing myotonic dystrophy type 1.
@ast
Rationally designed small mole ...... ing myotonic dystrophy type 1.
@en
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P1476
P2093
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P1433
P1476
Rationally designed small mole ...... sing myotonic dystrophy type 1
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921