Elevated hepatic multidrug resistance-associated protein 3/ATP-binding cassette subfamily C 3 expression in human obstructive cholestasis is mediated through tumor necrosis factor alpha and c-Jun NH2-terminal kinase/stress-activated protein kinase-s

Elevated hepatic multidrug resistance-associated protein 3/ATP-binding cassette subfamily C 3 expression in human obstructive cholestasis is mediated through tumor necrosis factor alpha and c-Jun NH2-terminal kinase/stress-activated protein kinase-s

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http://www.wikidata.org/entity/Q35815498

Q35815498

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Molecular mechanism of monoamine oxidase A gene regulation under inflammation and ischemia-like conditions: key roles of the transcription factors GATA2, Sp1 and TBP Role of PXR in Hepatic Cancer: Its Influences on Liver Detoxification Capacity and Cancer Progression Bile formation and secretion.Role of multidrug resistance-associated protein 4 in the basolateral efflux of hepatically derived enalaprilat.Quantitative assessment of the multiple processes responsible for bilirubin homeostasis in health and disease.Swertianlarin, isolated from Swertia mussotii Franch, increases detoxification enzymes and efflux transporters expression in rats.Oral administration of oleanolic acid, isolated from Swertia mussotii Franch, attenuates liver injury, inflammation, and cholestasis in bile duct-ligated rats.Toward predicting drug-induced liver injury: parallel computational approaches to identify multidrug resistance protein 4 and bile salt export pump inhibitors.Hepatic expression of detoxification enzymes is decreased in human obstructive cholestasis due to gallstone biliary obstruction Interleukin-18 Down-Regulates Multidrug Resistance-Associated Protein 2 Expression through Farnesoid X Receptor Associated with Nuclear Factor Kappa B and Yin Yang 1 in Human Hepatoma HepG2 Cells.Fibrates and cholestasis Swertianlarin, an Herbal Agent Derived from Swertia mussotii Franch, Attenuates Liver Injury, Inflammation, and Cholestasis in Common Bile Duct-Ligated Rats Liver Expression of Sulphotransferase 2A1 Enzyme Is Impaired in Patients with Primary Sclerosing Cholangitis: Lack of the Response to Enhanced Expression of PXR Canalicular membrane MRP2/ABCC2 internalization is determined by Ezrin Thr567 phosphorylation in human obstructive cholestasis Drug disposition alterations in liver disease: extrahepatic effects in cholestasis and nonalcoholic steatohepatitis.Enhanced membrane-tethered mucin 3 (MUC3) expression by a tetrameric branched peptide with a conserved TFLK motif inhibits bacteria adherence.Nuclear receptors as drug targets in cholestatic liver diseases.Distinct functions of JNK and c-Jun in oxidant-induced hepatocyte death.Prevention of gallstones by Lidan Granule: Insight into underlying mechanisms using a guinea pig model A perspective on efflux transport proteins in the liver Hepatic basolateral efflux contributes significantly to rosuvastatin disposition I: characterization of basolateral versus biliary clearance using a novel protocol in sandwich-cultured hepatocytes Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4.Loss of von Hippel-Lindau protein (VHL) increases systemic cholesterol levels through targeting hypoxia-inducible factor 2α and regulation of bile acid homeostasis.Phase 0 and phase III transport in various organs: combined concept of phases in xenobiotic transport and metabolism.Mitochondria-meditated pathways of organ failure upon inflammation.Effect of Liver Disease on Hepatic Transporter Expression and Function.Inhibition of Human Hepatic Bile Acid Transporters by Tolvaptan and Metabolites: Contributing Factors to Drug-Induced Liver Injury?Activation of p38 Mitogen-Activated Protein Kinase by Clotrimazole Induces Multidrug Resistance-Associated Protein 3 Activation through a Novel Transcriptional Element.Farnesoid X Receptor Agonists Obeticholic Acid and Chenodeoxycholic Acid Increase Bile Acid Efflux in Sandwich-Cultured Human Hepatocytes: Functional Evidence and Mechanisms.Biliary excretion of pravastatin and taurocholate in rats with bile salt export pump (Bsep) impairment.The molecular mechanism underlying the induction of hepatic MRP3 expression and function by omeprazole.

P2860

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P2860

Elevated hepatic multidrug resistance-associated protein 3/ATP-binding cassette subfamily C 3 expression in human obstructive cholestasis is mediated through tumor necrosis factor alpha and c-Jun NH2-terminal kinase/stress-activated protein kinase-s

Item

http://www.wikidata.org/entity/Q35815498

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

@zh-cn

name

Elevated hepatic multidrug res ...... ess-activated protein kinase-s

@ast

Elevated hepatic multidrug res ...... ess-activated protein kinase-s

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type

Item

label

Elevated hepatic multidrug res ...... ess-activated protein kinase-s

@ast

Elevated hepatic multidrug res ...... ess-activated protein kinase-s

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prefLabel

Elevated hepatic multidrug res ...... ess-activated protein kinase-s

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Elevated hepatic multidrug res ...... ess-activated protein kinase-s

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P1476

Elevated hepatic multidrug res ...... ess-activated protein kinase-s

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P2093

Huaizhi Wang

http://www.w3.org/2001/XMLSchema#string

James L Boyer

http://www.w3.org/2001/XMLSchema#string

Jin Chai

http://www.w3.org/2001/XMLSchema#string

Lei Chen

http://www.w3.org/2001/XMLSchema#string

Qiong Li

http://www.w3.org/2001/XMLSchema#string

Rongquan Wang

http://www.w3.org/2001/XMLSchema#string

Shi-Ying Cai

http://www.w3.org/2001/XMLSchema#string

Tianli Xiao

http://www.w3.org/2001/XMLSchema#string

Wensheng Chen

http://www.w3.org/2001/XMLSchema#string

Xiaochong He

http://www.w3.org/2001/XMLSchema#string

P2860

Characterization of 5'-flanking region of human MRP3

Tissue distribution and induction of human multidrug resistant protein 3

High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis

Enhanced expression of basolateral multidrug resistance protein isoforms Mrp3 and Mrp5 in rat liver by LPS

Transport activity of human MRP3 expressed in Sf9 cells: comparative studies with rat MRP3

Transcriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship with age-related macular degeneration.

Nuclear receptors RXRalpha:RARalpha are repressors for human MRP3 expression.

JNK MAPK pathway regulates constitutive transcription of CCL5 by human NK cells through SP1.

TNF-alpha mediates pseudorabies virus-induced apoptosis via the activation of p38 MAPK and JNK/SAPK signaling.

Membrane-type 1 matrix metalloproteinase is regulated by sp1 through the differential activation of AKT, JNK, and ERK pathways in human prostate tumor cells.

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1485-1494

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scholarly article

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10.1002/HEP.24801

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English

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2012-05-01T00:00:00Z

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51817444

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22105759

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multiple drug resistance

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3297707

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Elevated hepatic multidrug resistance-associated protein 3/ATP-binding cassette subfamily C 3 expression in human obstructive cholestasis is mediated through tumor necrosis factor alpha and c-Jun NH2-terminal kinase/stress-activated protein kinase-s

about

P2860

P2860

Elevated hepatic multidrug resistance-associated protein 3/ATP-binding cassette subfamily C 3 expression in human obstructive cholestasis is mediated through tumor necrosis factor alpha and c-Jun NH2-terminal kinase/stress-activated protein kinase-s

description

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P1433

P1476

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P2860

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P356

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P932

P356

P1433

P1476

P2093

P2860

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P356

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P478

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P698

P921

P932