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Quantification of drug transport function across the multiple resistance-associated protein 2 (Mrp2) in rat liversRelevance of Liver Failure for Anti-Infective Agents: From Pharmacokinetic Alterations to Dosage AdjustmentsRole of multidrug resistance-associated protein 4 in the basolateral efflux of hepatically derived enalaprilat.Altered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitisA metabolomic perspective of griseofulvin-induced liver injury in mice.Model-based approaches to predict drug-drug interactions associated with hepatic uptake transporters: preclinical, clinical and beyond.Using positron emission tomography to study transporter-mediated drug-drug interactions in tissues.Prediction of pharmacokinetics and drug-drug interactions when hepatic transporters are involved.Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP.Verapamil hepatic clearance in four preclinical rat models: towards activity-based scaling.Transporter-mediated Alterations in Patients with NASH Increase Systemic and Hepatic Exposure to an OATP and MRP2 Substrate.Gender-Specific Association Between ABCC2 -24C>T SNP and Reduction in Triglycerides in Chilean Patients Treated With Atorvastatin.The farnesoid X receptor agonist obeticholic acid upregulates biliary excretion of asymmetric dimethylarginine via MATE-1 during hepatic ischemia/reperfusion injury.Identification of genetic variants in pharmacokinetic genes associated with Ewing Sarcoma treatment outcome.Drug Transporters: Advances and Opportunities.Role of Hepatic Drug Transporters in Drug Development.Glucuronidation: driving factors and their impact on glucuronide dispositionCan BSEP Inhibition Testing In Drug Discovery And Development Reduce Liver Injury Risk? - An International Transporter Consortium Perspective
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 05 September 2012
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A perspective on efflux transport proteins in the liver
@en
A perspective on efflux transport proteins in the liver.
@nl
type
label
A perspective on efflux transport proteins in the liver
@en
A perspective on efflux transport proteins in the liver.
@nl
prefLabel
A perspective on efflux transport proteins in the liver
@en
A perspective on efflux transport proteins in the liver.
@nl
P2860
P356
P1476
A perspective on efflux transport proteins in the liver
@en
P2093
P2860
P304
P356
10.1038/CLPT.2012.79
P407
P50
P577
2012-09-05T00:00:00Z