Early CD4(+) T cell help prevents partial CD8(+) T cell exhaustion and promotes maintenance of Herpes Simplex Virus 1 latency.
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Molecular and cellular insights into T cell exhaustionDistinct roles of CD4+ T cell subpopulations in retroviral immunity: lessons from the Friend virus mouse modelIlluminating viral infections in the nervous systemPromotion of a subdominant CD8 T cell response during murine gammaherpesvirus 68 infection in the absence of CD4 T cell helpReversible nerve damage and corneal pathology in murine herpes simplex stromal keratitis.B7 costimulation molecules encoded by replication-defective, vhs-deficient HSV-1 improve vaccine-induced protection against corneal diseaseAgonistic anti-CD40 enhances the CD8+ T cell response during vesicular stomatitis virus infection.Immunization with different viral antigens alters the pattern of T cell exhaustion and latency in herpes simplex virus type 1-infected mice.Circulating herpes simplex type 1 (HSV-1)-specific CD8+ T cells do not access HSV-1 latently infected trigeminal ganglia.Autoimmune melanocyte destruction is required for robust CD8+ memory T cell responses to mouse melanomaCD4+ T cells inhibit the neu-specific CD8+ T-cell exhaustion during the priming phase of immune responses against breast cancerPD-L1-expressing dendritic cells contribute to viral resistance during acute HSV-1 infectionCD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitisDefining the herpes simplex virus-specific CD8+ T cell repertoire in C57BL/6 miceRecurrent herpetic stromal keratitis in mice: a model for studying human HSK.CD8+ T Cells Play a Bystander Role in Mice Latently Infected with Herpes Simplex Virus 1.The herpes simplex virus type 1 latency-associated transcript inhibits phenotypic and functional maturation of dendritic cells.Interferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8+ T Cells.Maintenance of T cell function in the face of chronic antigen stimulation and repeated reactivation for a latent virus infection.CD4(+) T-cell dependence of primary CD8(+) T-cell response against vaccinia virus depends upon route of infection and viral dose.Mucosal herpes immunity and immunopathology to ocular and genital herpes simplex virus infections.Enhanced CD8 T-cell anti-viral function and clinical disease in B7-H1-deficient mice requires CD4 T cells during encephalomyelitis.The Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8+ T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic RabbitsPD-L1/B7-H1 regulates the survival but not the function of CD8+ T cells in herpes simplex virus type 1 latently infected trigeminal ganglia.Asymptomatic memory CD8+ T cells: from development and regulation to consideration for human vaccines and immunotherapeuticsBroadening the repertoire of functional herpes simplex virus type 1-specific CD8+ T cells reduces viral reactivation from latency in sensory gangliaSTAT3 regulates proliferation and survival of CD8+ T cells: enhances effector responses to HSV-1 infection, and inhibits IL-10+ regulatory CD8+ T cells in autoimmune uveitis.Rapid host immune response and viral dynamics in herpes simplex virus-2 infection.The PD-1/PD-L1 (B7-H1) pathway in chronic infection-induced cytotoxic T lymphocyte exhaustion.CD8+ T cells patrol HSV-1-infected trigeminal ganglia and prevent viral reactivation.Herpes simplex virus-1 evasion of CD8+ T cell accumulation contributes to viral encephalitis.Dok-1 and Dok-2 Are Required To Maintain Herpes Simplex Virus 1-Specific CD8+ T Cells in a Murine Model of Ocular Infection.CNS-derived CCL21 is both sufficient to drive homeostatic CD4+ T cell proliferation and necessary for efficient CD4+ T cell migration into the CNS parenchyma following Toxoplasma gondii infection.Influenza-induced, helper-independent CD8+ T cell responses use CD40 costimulation at the late phase of the primary response.PD-L1/B7-H1 Inhibits Viral Clearance by Macrophages in HSV-1-Infected Corneas.Herpesviruses: Harmonious Pathogens but Relevant Cofactors in Other Diseases?Human Asymptomatic Epitope Peptide/CXCL10-Based Prime/Pull Vaccine Induces Herpes Simplex Virus-Specific Gamma Interferon-Positive CD107 CD8 T Cells That Infiltrate the Corneas and Trigeminal Ganglia of Humanized HLA Transgenic Rabbits and Protect agCD4 T cells control development and maintenance of brain-resident CD8 T cells during polyomavirus infection
P2860
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P2860
Early CD4(+) T cell help prevents partial CD8(+) T cell exhaustion and promotes maintenance of Herpes Simplex Virus 1 latency.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Early CD4(+) T cell help preve ...... erpes Simplex Virus 1 latency.
@ast
Early CD4(+) T cell help preve ...... erpes Simplex Virus 1 latency.
@en
type
label
Early CD4(+) T cell help preve ...... erpes Simplex Virus 1 latency.
@ast
Early CD4(+) T cell help preve ...... erpes Simplex Virus 1 latency.
@en
prefLabel
Early CD4(+) T cell help preve ...... erpes Simplex Virus 1 latency.
@ast
Early CD4(+) T cell help preve ...... erpes Simplex Virus 1 latency.
@en
P2093
P2860
P356
P1476
Early CD4(+) T cell help preve ...... erpes Simplex Virus 1 latency.
@en
P2093
Andrew J Lepisto
Brian S Sheridan
Gregory M Frank
Michael L Freeman
Robert L Hendricks
Thomas L Cherpes
P2860
P304
P356
10.4049/JIMMUNOL.0902373
P407
P577
2009-11-30T00:00:00Z