Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation. - Wikidata - awgldk - TriplyDB

Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation.

Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation.

http://www.wikidata.org/entity/Q35818714

about

The NEDD8 modification pathway in plants Posttranslational control of HuR function Multiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosis Chemogenomic Study of Carboplatin in Saccharomyces cerevisiae: Inhibition of the NEDDylation Process Overcomes Cellular Resistance Mediated by HuR and Cullin Proteins Protein neddylation: beyond cullin-RING ligases.PPARγ neddylation essential for adipogenesis is a potential target for treating obesity.Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy Neddylation and deneddylation in cardiac biology The neddylation-cullin 2-RBX1 E3 ligase axis targets tumor suppressor RhoB for degradation in liver cancer.Methylthioadenosine (MTA) Regulates Liver Cells Proteome and Methylproteome: Implications in Liver Biology and Disease Suppression of glioblastoma by targeting the overactivated protein neddylation pathway.NEDD8 Ultimate Buster 1 Long (NUB1L) Protein Suppresses Atypical Neddylation and Promotes the Proteasomal Degradation of Misfolded Proteins.The C-terminal RNA binding motif of HuR is a multi-functional domain leading to HuR oligomerization and binding to U-rich RNA targets.The mRNA-stabilizing factor HuR protein is targeted by β-TrCP protein for degradation in response to glycolysis inhibition.Suppression of tumor angiogenesis by targeting the protein neddylation pathway.Targeting neddylation in cancer therapy.MDM2's social network.The role and therapeutic implications of RING-finger E3 ubiquitin ligases in hepatocellular carcinoma.Overactivated neddylation pathway as a therapeutic target in lung cancer.Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer Deregulated neddylation in liver fibrosis.Neddylation controls basal MKK7 kinase activity in breast cancer cells.MDM2 but not MDM4 promotes retinoblastoma cell proliferation through p53-independent regulation of MYCN translation.Human antigen R contributes to hepatic stellate cell activation and liver fibrosis.Knockdown of GTPBP4 inhibits cell growth and survival in human hepatocellular carcinoma and its prognostic significance.RNA Binding Protein Regulation and Cross-Talk in the Control of AU-rich mRNA Fate.CCAAT/enhancer binding protein δ in macrophages contributes to immunosuppression and inhibits phagocytosis in nasopharyngeal carcinoma.The liver-specific microRNA-122*, the complementary strand of microRNA-122, acts as a tumor suppressor by modulating the p53/mouse double minute 2 homolog circuitry.Protein neddylation and its alterations in human cancers for targeted therapy.The Jun/miR-22/HuR regulatory axis contributes to tumourigenesis in colorectal cancer.Post-Translational Modifications and RNA-Binding Proteins.Role of novel histone modifications in cancer.Lymphotoxin α, a novel target of posttranscriptional gene regulation by HuR in HepG2 cells.MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

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P2860

Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation.

http://www.wikidata.org/entity/Q35818714

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Murine double minute 2 regulat ...... on cancer through NEDDylation.

@ast

Murine double minute 2 regulat ...... on cancer through NEDDylation.

@en

type

label

Murine double minute 2 regulat ...... on cancer through NEDDylation.

@ast

Murine double minute 2 regulat ...... on cancer through NEDDylation.

@en

prefLabel

Murine double minute 2 regulat ...... on cancer through NEDDylation.

@ast

Murine double minute 2 regulat ...... on cancer through NEDDylation.

@en

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P1476

Murine double minute 2 regulat ...... on cancer through NEDDylation.

@en

P2093

Ana Belén de la Hoz

http://www.w3.org/2001/XMLSchema#string

Arkaitz Carracedo

http://www.w3.org/2001/XMLSchema#string

Begoña Rodríguez-Iruretagoyena

http://www.w3.org/2001/XMLSchema#string

Dimitris P Xirodimas

http://www.w3.org/2001/XMLSchema#string

Francisco Javier Bustamante

http://www.w3.org/2001/XMLSchema#string

Manuel S Rodríguez

http://www.w3.org/2001/XMLSchema#string

Marcella Sini

http://www.w3.org/2001/XMLSchema#string

Marta Varela-Rey

http://www.w3.org/2001/XMLSchema#string

María L Martínez-Chantar

http://www.w3.org/2001/XMLSchema#string

Nieves Embade

http://www.w3.org/2001/XMLSchema#string

P2860

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

Ubiquitin-mediated proteolysis of HuR by heat shock

Regulation of nucleolar signalling to p53 through NEDDylation of L11

Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1.

SUMO-1 modification activates the transcriptional response of p53

The mRNA nuclear export factor Hpr1 is regulated by Rsp5-mediated ubiquitylation.

K252a inhibits the oncogenic properties of Met, the HGF receptor

Posttranscriptional regulation of cancer traits by HuR

Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity

HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis

P304

1237-1248

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scholarly article

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10.1002/HEP.24795

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P407

P433

4

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P478

55

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David Fernández-Ramos

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2012-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

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51807831

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22095636

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3298572

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