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Mdm2 as a chromatin modifierInhibition of the MDM2 E3 Ligase induces apoptosis and autophagy in wild-type and mutant p53 models of multiple myeloma, and acts synergistically with ABT-737MDM2 and HIF1alpha expression levels in different histologic subtypes of malignant pleural mesothelioma: correlation with pathological and clinical data.BAI1 regulates spatial learning and synaptic plasticity in the hippocampusMDM2 oligomers: antagonizers of the guardian of the genome.Differential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells.RASSF10 suppresses colorectal cancer growth by activating P53 signaling and sensitizes colorectal cancer cell to docetaxel.The alternative translated MDMX(p60) isoform regulates MDM2 activity.Impact of the MDM2 splice-variants MDM2-A, MDM2-B and MDM2-C on cytotoxic stress response in breast cancer cellsDCAF1 controls T-cell function via p53-dependent and -independent mechanismsSCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence.USP7 Enforces Heterochromatinization of p53 Target Promoters by Protecting SUV39H1 from MDM2-Mediated Degradation.Novel insights about the MDM2/MDM4 heterodimer.Characterization of cancer-associated missense mutations in MDM2.MDM2 facilitates adipocyte differentiation through CRTC-mediated activation of STAT3Synergistic targeting of malignant pleural mesothelioma cells by MDM2 inhibitors and TRAIL agonists.p53, p63 and p73 in the wonderland of S. cerevisiae.Allosteric Interactions by p53 mRNA Govern HDM2 E3 Ubiquitin Ligase Specificity under Different Conditions.Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma.Identification of XBP1-u as a novel regulator of the MDM2/p53 axis using an shRNA library.Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.USP7 small-molecule inhibitors interfere with ubiquitin binding.Prediction of protein disorder based on IUPred.Foretinib (GSK1363089) induces p53-dependent apoptosis in endometrial cancer.
P2860
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P2860
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
MDM2's social network.
@en
type
label
MDM2's social network.
@en
prefLabel
MDM2's social network.
@en
P2860
P356
P1433
P1476
MDM2's social network.
@en
P2093
R Fåhraeus
V Olivares-Illana
P2860
P2888
P304
P356
10.1038/ONC.2013.410
P407
P577
2013-10-07T00:00:00Z
P5875
P6179
1015924490