A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis
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Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration.Inhibition of β-Glucocerebrosidase Activity Preserves Motor Unit Integrity in a Mouse Model of Amyotrophic Lateral Sclerosis.Triheptanoin Protects Motor Neurons and Delays the Onset of Motor Symptoms in a Mouse Model of Amyotrophic Lateral SclerosisGlycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of SBMA muscle modified by high-fat dietA high-fat jelly diet restores bioenergetic balance and extends lifespan in the presence of motor dysfunction and lumbar spinal cord motor neuron loss in TDP-43A315T mutant C57BL6/J mice.Rescue of Metabolic Alterations in AR113Q Skeletal Muscle by Peripheral Androgen Receptor Gene Silencing.AMPK Signalling and Defective Energy Metabolism in Amyotrophic Lateral Sclerosis.The interplay between metabolic homeostasis and neurodegeneration: insights into the neurometabolic nature of amyotrophic lateral sclerosis.The Role of Skeletal Muscle in Amyotrophic Lateral Sclerosis.Additive Neuroprotective Effects of the Multifunctional Iron Chelator M30 with Enriched Diet in a Mouse Model of Amyotrophic Lateral Sclerosis.Therapeutic applications of dichloroacetate and the role of glutathione transferase zeta-1.Metabolic Dysfunctions in Amyotrophic Lateral Sclerosis Pathogenesis and Potential Metabolic TreatmentsDevelopment of a high-throughput method for real-time assessment of cellular metabolism in intact long skeletal muscle fibre bundles.PGC-1α Silencing Compounds the Perturbation of Mitochondrial Function Caused by Mutant SOD1 in Skeletal Muscle of ALS Mouse Model.Amyotrophic lateral sclerosis and denervation alter sphingolipids and up-regulate glucosylceramide synthaseWhat is "Hyper" in the ALS Hypermetabolism?Motor neuron disease: Are diabetes and amyotrophic lateral sclerosis related?Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice.Lipid Metabolism and Survival Across the Frontotemporal Dementia-Amyotrophic Lateral Sclerosis Spectrum: Relationships to Eating Behavior and Cognition.Liver X Receptor Genes Variants Modulate ALS Phenotype.Beneficial Effects of Multitarget Iron Chelator on Central Nervous System and Gastrocnemius Muscle in SOD1(G93A) Transgenic ALS Mice.Pyruvate dehydrogenase kinase 2 and 4 gene deficiency attenuates nociceptive behaviors in a mouse model of acute inflammatory pain.Neuronal Lipid Metabolism: Multiple Pathways Driving Functional Outcomes in Health and Disease.Sphingolipid Metabolism Is Dysregulated at Transcriptomic and Metabolic Levels in the Spinal Cord of an Animal Model of Amyotrophic Lateral Sclerosis.Metabolic Dysregulation in Amyotrophic Lateral Sclerosis: Challenges and Opportunities.Metabolic Reprogramming in Amyotrophic Lateral Sclerosis.Omics to Explore Amyotrophic Lateral Sclerosis Evolution: the Central Role of Arginine and Proline Metabolism.Energy metabolism in ALS: an underappreciated opportunity?Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis.Swim Training Modulates Skeletal Muscle Energy Metabolism, Oxidative Stress, and Mitochondrial Cholesterol Content in Amyotrophic Lateral Sclerosis Mice.Role of the Pyruvate Dehydrogenase Complex in Metabolic Remodeling: Differential Pyruvate Dehydrogenase Complex Functions in Metabolism
P2860
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P2860
A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
A metabolic switch toward lipi ...... amyotrophic lateral sclerosis
@ast
A metabolic switch toward lipi ...... amyotrophic lateral sclerosis
@en
type
label
A metabolic switch toward lipi ...... amyotrophic lateral sclerosis
@ast
A metabolic switch toward lipi ...... amyotrophic lateral sclerosis
@en
prefLabel
A metabolic switch toward lipi ...... amyotrophic lateral sclerosis
@ast
A metabolic switch toward lipi ...... amyotrophic lateral sclerosis
@en
P2093
P2860
P356
P1476
A metabolic switch toward lipi ...... amyotrophic lateral sclerosis
@en
P2093
Alexandre Henriques
Andoni Echaniz-Laguna
Anna Schlagowski
Anne-Laurence Boutillier
Aurelia Vernay
Frédérique René
Jean-Philippe Loeffler
Joffrey Zoll
Lavinia Palamiuc
Shyuan T Ngo
P2860
P304
P356
10.15252/EMMM.201404433
P577
2015-03-27T00:00:00Z