Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesity
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Potential involvement of adipocyte insulin resistance in obesity-associated up-regulation of adipocyte lysophospholipase D/autotaxin expressionStructure/Function Relationships of Adipose Phospholipase A2 Containing a Cys-His-His Catalytic TriadRegulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphatePhospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizationsA metabolically-stabilized phosphonate analog of lysophosphatidic acid attenuates collagen-induced arthritisIdentification of an insulin-regulated lysophospholipase with homology to neuropathy target esteraseDiscovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.alpha- and beta-substituted phosphonate analogs of LPA as autotaxin inhibitorsCancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclastsLPA receptor signaling: pharmacology, physiology, and pathophysiology.Lysophospholipid receptor nomenclature review: IUPHAR Review 8.Adiposopathy: how do diet, exercise and weight loss drug therapies improve metabolic disease in overweight patients?Autotaxin downregulates LPS-induced microglia activation and pro-inflammatory cytokines production.Adipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid.Lysophosphatidic acid signalling in developmentRegulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.Serum autotaxin is independently associated with hepatic steatosis in women with severe obesity.Ligand-based autotaxin pharmacophore models reflect structure-based docking results.Production of lysophosphatidic acid in blister fluid: involvement of a lysophospholipase D activityBrain-adipose tissue cross talk.Autotaxin/ENPP2 regulates oligodendrocyte differentiation in vivo in the developing zebrafish hindbrain.Autotaxin Expression Is Regulated at the Post-transcriptional Level by the RNA-binding Proteins HuR and AUF1.Autotaxin, a lysophospholipase D with pleomorphic effects in oncogenesis and cancer progressionSerum Autotaxin/ENPP2 correlates with insulin resistance in older humans with obesity.Thematic review series: adipocyte biology. Sympathetic and sensory innervation of white adipose tissue.Mammary Adipose Tissue-Derived Lysophospholipids Promote Estrogen Receptor-Negative Mammary Epithelial Cell Proliferation.Autotaxin (ATX): a multi-functional and multi-modular protein possessing enzymatic lysoPLD activity and matricellular propertiesMetabolite Signatures of Metabolic Risk Factors and their Longitudinal ChangesAbsence of the lysophosphatidic acid receptor LPA1 results in abnormal bone development and decreased bone mass.Analyses of group III secreted phospholipase A2 transgenic mice reveal potential participation of this enzyme in plasma lipoprotein modification, macrophage foam cell formation, and atherosclerosis.The effects of aspirin and fish oil consumption on lysophosphatidylcholines and lysophosphatidic acids and their correlates with platelet aggregation in adults with diabetes mellitus.Arguing the case for the autotaxin-lysophosphatidic acid-lipid phosphate phosphatase 3-signaling nexus in the development and complications of atherosclerosis.Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer.Cutting-edge issues in primary biliary cirrhosis.Lysophosphatidic acid-1-receptor targeting agents for fibrosis.The role and therapeutic potential of the autotaxin-lysophosphatidate signalling axis in breast cancer.Lysophosphatidic acid as a lipid mediator with multiple biological actions.Intestinal phospholipid and lysophospholipid metabolism in cardiometabolic disease.Lysophosphatidic acid (LPA) as a pro-fibrotic and pro-oncogenic factor: a pivotal target to improve the radiotherapy therapeutic index.Autotaxin inhibitors: a patent review (2012-2016).
P2860
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P2860
Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesity
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Autotaxin is released from adi ...... te differentiation and obesity
@ast
Autotaxin is released from adi ...... te differentiation and obesity
@en
type
label
Autotaxin is released from adi ...... te differentiation and obesity
@ast
Autotaxin is released from adi ...... te differentiation and obesity
@en
prefLabel
Autotaxin is released from adi ...... te differentiation and obesity
@ast
Autotaxin is released from adi ...... te differentiation and obesity
@en
P2093
P2860
P356
P1476
Autotaxin is released from adi ...... te differentiation and obesity
@en
P2093
Edwige Tellier
Gilles Ferry
Isabelle Naime
Jean Pierre Galizzi
Jean Sébastien Saulnier-Blache
Jérémie Boucher
Marianne Rodriguez
P2860
P304
18162-18169
P356
10.1074/JBC.M301158200
P407
P577
2003-03-17T00:00:00Z