A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis - Wikidata - awgldk - TriplyDB

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

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Regulation of TAZ in cancer G Protein-Coupled Receptors in Cancer YAP-Mediated Mechanotransduction in Skeletal Muscle Mechanisms of Hippo pathway regulation A Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue Sarcomas MST kinases in development and disease Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer The Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin, Hippo, and Warts DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2 The Hippo pathway in tissue homeostasis and regeneration.Transforming growth factor-beta1 suppresses hepatocellular carcinoma proliferation via activation of Hippo signaling Deubiquitylating enzyme USP9x regulates hippo pathway activity by controlling angiomotin protein turnover The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity Role of the YAP Oncoprotein in Priming Ras-Driven Rhabdomyosarcoma.YAP activates the Hippo pathway in a negative feedback loop.The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1.Inactivation of hypoxia-induced YAP by statins overcomes hypoxic resistance tosorafenib in hepatocellular carcinoma cells.The benefits of local depletion: The centrosome as a scaffold for ubiquitin-proteasome-mediated degradation An evolutionarily conserved negative feedback mechanism in the Hippo pathway reflects functional difference between LATS1 and LATS2 Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2.YAP1 enhances cell proliferation, migration, and invasion of gastric cancer in vitro and in vivo Overexpression of Yes-associated protein and its association with clinicopathological features of hepatocellular carcinoma: A meta-analysis.eIF5A-PEAK1 Signaling Regulates YAP1/TAZ Protein Expression and Pancreatic Cancer Cell Growth.MRTF potentiates TEAD-YAP transcriptional activity causing metastasis.Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD).Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis.Yap1 plays a protective role in suppressing free fatty acid-induced apoptosis and promoting beta-cell survival.The Hippo pathway in intestinal regeneration and disease.Molecular Features of the YAP Inhibitor Verteporfin: Synthesis of Hexasubstituted Dipyrrins as Potential Inhibitors of YAP/TAZ, the Downstream Effectors of the Hippo Pathway.The LATS1 and LATS2 tumor suppressors: beyond the Hippo pathway.Signaling and epigenetic mechanisms of intestinal stem cells and progenitors: insight into crypt homeostasis, plasticity, and niches.Matrix stiffness induces epithelial-mesenchymal transition and promotes chemoresistance in pancreatic cancer cells.YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis.Repression of YAP by NCTD disrupts NSCLC progression.Knockdown of Yes-Associated Protein Induces the Apoptosis While Inhibits the Proliferation of Human Periodontal Ligament Stem Cells through Crosstalk between Erk and Bcl-2 Signaling Pathways.Dual roles of yes-associated protein (YAP) in colorectal cancer.Characterization of Hippo Pathway Components by Gene Inactivation.An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice.Angiomotin-like 2 interacts with and negatively regulates AKT.Hyaluronic acid enhances cell migration and invasion via the YAP1/TAZ-RHAMM axis in malignant pleural mesothelioma.

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A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

http://www.wikidata.org/entity/Q35829995

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

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A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

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type

label

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

@ast

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

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prefLabel

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

@ast

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

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A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

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Baodong Qin

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Duojia Pan

http://www.w3.org/2001/XMLSchema#string

Fa-Xing Yu

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Hyun Woo Park

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Koji Taniguchi

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Kun-Liang Guan

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Qian Chen

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Steven W Plouffe

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Toshiro Moroishi

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Zhipeng Meng

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P2860

Genome engineering using the CRISPR-Cas9 system

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

TEAD mediates YAP-dependent gene induction and growth control

The hippo signaling pathway in development and cancer

The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1

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1271-1284

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10.1101/GAD.262816.115

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12

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4495398

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