Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP - Wikidata - awgldk - TriplyDB

Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP

Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP

http://www.wikidata.org/entity/Q35830000

about

The MST/Hippo Pathway and Cell Death: A Non-Canonical Affair The Roles of NDR Protein Kinases in Hippo Signalling Mechanisms of Hippo pathway regulation Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer The Hippo pathway in tissue homeostasis and regeneration.A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis YAP activates the Hippo pathway in a negative feedback loop.Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.YAP Nuclear Localization in the Absence of Cell-Cell Contact Is Mediated by a Filamentous Actin-dependent, Myosin II- and Phospho-YAP-independent Pathway during Extracellular Matrix Mechanosensing Multiple Mechanisms Cooperate to Constitutively Exclude the Transcriptional Co-Activator YAP from the Nucleus During Murine Oogenesis.An evolutionarily conserved negative feedback mechanism in the Hippo pathway reflects functional difference between LATS1 and LATS2 Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis.Yes-associated protein 1 promotes papillary thyroid cancer cell proliferation by activating the ERK/MAPK signaling pathway.CDK5RAP2 interaction with components of the Hippo signaling pathway may play a role in primary microcephaly.YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis.Phosphorylation by NLK inhibits YAP-14-3-3-interactions and induces its nuclear localization.Osmotic stress-induced phosphorylation by NLK at Ser128 activates YAP.Hippo Signaling in the Liver Regulates Organ Size, Cell Fate, and Carcinogenesis.The Hippo pathway in intestinal regeneration and disease.YAP/TAZ at the Roots of Cancer.Hippo vs. Crab: tissue-specific functions of the mammalian Hippo pathway.The LATS1 and LATS2 tumor suppressors: beyond the Hippo pathway.Signaling and epigenetic mechanisms of intestinal stem cells and progenitors: insight into crypt homeostasis, plasticity, and niches.The nonreceptor tyrosine kinase c-Src attenuates SCF(β-TrCP) E3-ligase activity abrogating Taz proteasomal degradation.Characterization of Hippo Pathway Components by Gene Inactivation.An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice.Deubiquitylase USP9X suppresses tumorigenesis by stabilizing large tumor suppressor kinase 2 (LATS2) in the Hippo pathway.Dysregulation of YAP by the Hippo pathway is involved in intervertebral disc degeneration, cell contact inhibition, and cell senescence.YAP/TAZ-CDC42 signaling regulates vascular tip cell migration.YAP needs Nemo to guide a Hippo.Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ.Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.α-Catenin-dependent cytoskeletal tension controls Yap activity in the heart.Human Papillomavirus E6 interaction with cellular PDZ domain proteins modulates YAP nuclear localization.YAP and TAZ in Lung Cancer: Oncogenic Role and Clinical Targeting.SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity.

P2860

Q26744308-E8B78CDF-1B0E-4E14-B98A-58CB2E8E4F70 Q26746889-F90470E5-0E9D-4767-B341-71CFF7D20C77 Q26771285-3A135013-4B05-456D-985C-C84A098F31E7 Q28269498-EC32CF65-D87F-4637-81D5-3AF0FCB60E1D Q33628097-843C4593-A016-430C-A25D-CC041904EE50 Q35829995-5DD9F1FB-4848-4D82-92B9-666B65C01E3F Q36293511-40031F99-C6BC-4C78-A104-26F99BF89B1A Q36459320-D17DF869-2AA9-41E1-946E-E8F250543D18 Q36744713-AE2CBBD3-8F7E-4654-91ED-D4087C0E445A Q37082068-2FF43F83-6520-4F47-8EAB-A2C105D43BA3 Q37269215-8B08110C-F60B-4B4E-9A94-516BCE763D1F Q37545029-75AFD045-7E8B-48F1-B25F-668AB53C7502 Q37706975-80C92B9F-F725-40B7-89DF-B4C40A6ECC38 Q37710011-03B8FC61-E5E4-4CA6-8D3E-DE95DF3737D2 Q37714184-12398A43-2902-40C1-8954-733670BAD0C5 Q38407569-CAA61296-DF59-4B87-84A7-5C3B7150EC0A Q38407576-07EF3306-FB46-43FB-A7E5-4D6549BBF024 Q38779591-D89A33FC-AAE7-47C5-A6DD-D4EF3D018CF2 Q38826172-A2F745B4-8250-4C31-95C3-3EE357FAD61F Q38864941-1A2C5323-7607-4DDE-9CEC-CEEE2C9AF895 Q39081825-3BF6085C-38B2-42BF-B597-AF9C29B7C58E Q39394211-F6632E35-0D49-4F25-8333-1E603BD10A85 Q39394470-F6898317-2542-4060-86E3-D7F3A83EF926 Q40352974-0765710E-BC4D-46CA-8C90-53A8762CDC54 Q45423657-113F3865-D3FE-46A8-9133-EBF759ECA17D Q46062152-2788D1A3-B8EC-4BD5-9661-9662A2135C3F Q47354887-CDC9C9E1-4CBD-4E7F-A8BF-6B6F421F917A Q49545706-3D53264D-C492-4EEF-A5B4-CB1181C17141 Q49647076-DBC48A73-6968-4582-B243-370CA3B8784C Q50165412-3C0557D3-4C33-4ED4-B47D-451513D80063 Q50482980-D79BB519-5A2C-4523-958C-910EE18EAC57 Q50883426-94A5DCF4-7628-4613-93BE-F82833F7A983 Q52375225-A9966996-BD56-4227-AD2E-B760AE2DB6E6 Q52392798-215F3ECA-512A-4A33-B0BB-A657C781D60B Q53686708-7A2815D8-7D8B-4DD2-8FBF-9E31D49FB4DD Q55282550-57197003-566A-4D5E-8B0D-1AE251393C34

P2860

Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP

http://www.wikidata.org/entity/Q35830000

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

Homeostatic control of Hippo s ...... ous activating mutation in YAP

@ast

Homeostatic control of Hippo s ...... ous activating mutation in YAP

@en

type

label

Homeostatic control of Hippo s ...... ous activating mutation in YAP

@ast

Homeostatic control of Hippo s ...... ous activating mutation in YAP

@en

prefLabel

Homeostatic control of Hippo s ...... ous activating mutation in YAP

@ast

Homeostatic control of Hippo s ...... ous activating mutation in YAP

@en

P1433

Q35830000-D25F5DCB-8054-4663-9B6E-CDFFF828A2F6

P1476

Q35830000-2711BEA5-F723-4331-A933-6B55EA49B4DC

P2093

Q35830000-029BA0A7-B427-4E7B-A9FE-377372449990

Q35830000-037301DD-909A-4CF1-9E8E-0BE6BF267FB7

Q35830000-23C96EF8-4C03-4713-A7BB-436179C450F6

Q35830000-348C6A3D-4824-4DEE-A815-F7BA94F38861

Q35830000-366010CF-93D9-40AA-8F77-D12AEFE07B03

Q35830000-397874A1-CBF3-4984-AC68-96A2A3402C45

Q35830000-43C72F1B-78A4-4C2B-86C4-D606DD9ED336

Q35830000-5D59C085-DA49-4837-B1CD-3FC2F6D9202C

Q35830000-6BA0045D-7010-46D5-9D2D-50FD69D3234B

Q35830000-89554388-318D-4240-90DA-40BC5EB74961

P2860

Q35830000-022DFBC7-0354-41BA-BC25-EFA3DD353806

Q35830000-07A33702-128C-4F3E-90E1-DC7E396F595D

Q35830000-0F75A343-2CD0-4FD2-B797-24BF0126E02D

Q35830000-11EE8F60-2E17-405C-8C77-F03F46B43BFF

Q35830000-1245FB4B-357B-415B-8A7F-E68DB87B703C

Q35830000-1ADEFA58-D683-4533-892E-9E405D5917FE

Q35830000-1DCD1347-09C7-4F88-B844-2882A5994BAA

Q35830000-2683B518-C2AE-44DF-BA50-78CA7D677275

Q35830000-2B2262F0-5AE3-4037-BCB5-85A056C33A1E

Q35830000-34BBCE62-6608-4DED-A686-159331BE28D8

P304

Q35830000-4F3E4951-46E8-488B-BFA3-CC45B9FCE642

P31

Q35830000-B66E5721-23F1-4ABC-A6E7-7A0456BE43D3

P356

Q35830000-B19DAD86-B6F9-4B96-9A73-2672DEB56304

P433

Q35830000-085D63E5-D9CC-4FAC-9B09-9E68C26D3278

P478

Q35830000-82B64E5C-EB78-4D27-9DBA-7F21D0E82DA2

P577

Q35830000-61D69FC2-16DE-44B1-A25E-9C0DAD379282

P5875

Q35830000-92B7FA90-61B8-49AA-A24D-23E4D14EAD64

P698

Q35830000-70DDBFBE-F4CA-4BB4-9F5E-BB2A887C0E17

P932

Q35830000-E4311A02-D8B0-451B-AEEC-06A2FEFCC05C

P356

P1433

Genes & Development

P1476

Homeostatic control of Hippo s ...... ous activating mutation in YAP

@en

P2093

Bo Huang

http://www.w3.org/2001/XMLSchema#string

Duojia Pan

http://www.w3.org/2001/XMLSchema#string

Hiroshi Nojima

http://www.w3.org/2001/XMLSchema#string

Jing Cai

http://www.w3.org/2001/XMLSchema#string

Karen Kate David

http://www.w3.org/2001/XMLSchema#string

Kyung-Suk Choi

http://www.w3.org/2001/XMLSchema#string

Nailing Zhang

http://www.w3.org/2001/XMLSchema#string

Norikazu Yabuta

http://www.w3.org/2001/XMLSchema#string

Qian Chen

http://www.w3.org/2001/XMLSchema#string

Robert A Anders

http://www.w3.org/2001/XMLSchema#string

P2860

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Tumor suppressor LATS1 is a negative regulator of oncogene YAP

The hippo signaling pathway in development and cancer

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

Expression of Yes-associated protein in common solid tumors

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

P304

1285-1297

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1101/GAD.264234.115

http://www.w3.org/2001/XMLSchema#string

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

29

http://www.w3.org/2001/XMLSchema#string

P577

2015-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

279264855

http://www.w3.org/2001/XMLSchema#string

P698

26109051

http://www.w3.org/2001/XMLSchema#string

P932

4495399

http://www.w3.org/2001/XMLSchema#string