Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis - Wikidata - awgldk - TriplyDB

Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis

Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis

http://www.wikidata.org/entity/Q35834086

about

Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis Hepatolithiasis and intrahepatic cholangiocarcinoma: A review.Hepatocellular carcinoma mouse models: Hepatitis B virus-associated hepatocarcinogenesis and haploinsufficient tumor suppressor genes Animal Models for Fibrotic Liver Diseases: What We Have, What We Need, and What Is under Development An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of Cholangiocarcinoma Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer TLR4 Deficiency Protects against Hepatic Fibrosis and Diethylnitrosamine-Induced Pre-Carcinogenic Liver Injury in Fibrotic Liver HCV Tumor Promoting Effect Is Dependent on Host Genetic Background Pex11p plays a primary role in medium-chain fatty acid oxidation, a process that affects peroxisome number and size in Saccharomyces cerevisiae.Immunopathogenic Mechanisms of Autoimmune Hepatitis: How Much Do We Know from Animal Models?X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C Hepatocyte IKK2 protects Mdr2-/- mice from chronic liver failure Minichromosome maintenance helicase paralog MCM9 is dispensible for DNA replication but functions in germ-line stem cells and tumor suppression Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks.xCT deficiency accelerates chemically induced tumorigenesis.ABCB4 missense mutations D243A, K435T, G535D, I490T, R545C, and S978P significantly impair the lipid floppase and likely predispose to secondary pathologies in the human population.Bile formation and secretion.Novel model of antigen-specific induction of bile duct injury.Vitamin D modulates biliary fibrosis in ABCB4-deficient mice.Experimental models of hepatocellular carcinoma ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth Metabolic profiling of bile in cholangiocarcinoma using in vitro magnetic resonance spectroscopy Characterization of the rat mdr2 promoter and its regulation by the transcription factor Sp1.Deciphering the nuclear bile acid receptor FXR paradigm.Vascular profile characterization of liver tumors by magnetic resonance imaging using hemodynamic response imaging in mice Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation Specific genomic and transcriptomic aberrations in tumors induced by partial hepatectomy of a chronically inflamed murine liver.S-nitrosylation from GSNOR deficiency impairs DNA repair and promotes hepatocarcinogenesis Transcript profiling identifies iqgap2(-/-) mouse as a model for advanced human hepatocellular carcinoma.Differences in phosphatidylcholine and bile acids in bile from Egyptian and UK patients with and without cholangiocarcinoma Fibrosis in autoimmune and cholestatic liver disease Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging.NF-κB and STAT3 - key players in liver inflammation and cancer Trigger mechanisms of secondary sclerosing cholangitis in critically ill patients.Cholic acid induces a Cftr dependent biliary secretion and liver growth response in mice.Evaluation of 11C-acetate and 18F-FDG PET/CT in mouse multidrug resistance gene-2 deficient mouse model of hepatocellular carcinoma.Inflammatory models drastically alter tumor growth and the immune microenvironment in hepatocellular carcinoma.Isolation and characterization of liver epithelial cell lines from wild-type and mutant TgN737Rpw mice.Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice.

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Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis

http://www.wikidata.org/entity/Q35834086

description

1994 nî lūn-bûn

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1994年の論文

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1994年論文

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1994年論文

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1994年論文

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1994年論文

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1994年論文

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1994年论文

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1994年论文

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1994年论文

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name

Mice with homozygous disruptio ...... gitis and hepatocarcinogenesis

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Mice with homozygous disruptio ...... gitis and hepatocarcinogenesis

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type

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Mice with homozygous disruptio ...... gitis and hepatocarcinogenesis

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Mice with homozygous disruptio ...... gitis and hepatocarcinogenesis

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Mice with homozygous disruptio ...... gitis and hepatocarcinogenesis

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Mice with homozygous disruptio ...... gitis and hepatocarcinogenesis

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The American Journal of Pathology

P1476

Mice with homozygous disruptio ...... gitis and hepatocarcinogenesis

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P2093

Dingemans KP

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Groen AK

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Mauad TH

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Notenboom RG

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Oude Elferink RP

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Schinkel AH

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Smit JJ

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Verkruisen RP

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van Nieuwkerk CM

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van den Bergh Weerman MA

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P2860

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins

Byler disease. Fatal familial intrahepatic cholestasis in an Amish kindred

Induction of hepatic peroxisome proliferation in nonrodent species, including primates

Simplified mammalian DNA isolation procedure

Characterizations of and interactions between bile ductule cells and hepatocytes in early stages of rat hepatocarcinogenesis induced by ethionine.

Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities.

Antimitochondrial antibody negative primary biliary cirrhosis: a distinct syndrome of autoimmune cholangitis

Idiopathic adulthood ductopenia presenting with chronic recurrent cholestasis. A case report.

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

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1237-1245

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