The HIV-1 virion-associated protein vpr is a coactivator of the human glucocorticoid receptor.
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The Vpr protein from HIV-1: distinct roles along the viral life cycleTumor necrosis factor alpha receptor- and Fas-associated FLASH inhibit transcriptional activity of the glucocorticoid receptor by binding to and interfering with its interaction with p160 type nuclear receptor coactivatorsImmune modulation of the hypothalamic-pituitary-adrenal (HPA) axis during viral infectionViral calciomics: interplays between Ca2+ and virusThe HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptorGlucocorticoid-independent modulation of GR activity: Implications for immunotherapyDifferential recruitment of coactivator RIP140 by Ah and estrogen receptors. Absence of a role for LXXLL motifsCarboxyl terminus of hVIP/mov34 is critical for HIV-1-Vpr interaction and glucocorticoid-mediated signalingHIV-1 Vpr induces apoptosis through caspase 9 in T cells and peripheral blood mononuclear cellsHuman immunodeficiency virus type 1 (HIV-1) Vpr-regulated cell death: insights into mechanismHIV-1 Vpr enhances PPARβ/δ-mediated transcription, increases PDK4 expression, and reduces PDC activityNuclear export is evolutionarily conserved in CVC paired-like homeobox proteins and influences protein stability, transcriptional activation, and extracellular secretion.Rho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling systemFunctional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest.HIV-1 Vpr induces adipose dysfunction in vivo through reciprocal effects on PPAR/GR co-regulation.Genetic variation and HIV-associated neurologic disease.A conserved dileucine-containing motif in p6(gag) governs the particle association of Vpx and Vpr of simian immunodeficiency viruses SIV(mac) and SIV(agm)Vpr protein of human immunodeficiency virus type 1 binds to 14-3-3 proteins and facilitates complex formation with Cdc25C: implications for cell cycle arrestHuman immunodeficiency virus type 1 Vpr impairs dendritic cell maturation and T-cell activation: implications for viral immune escape.The functions of the HIV1 protein Vpr and its action through the DCAF1.DDB1.Cullin4 ubiquitin ligase.Nuclear receptor coactivator p160 proteins enhance the HIV-1 long terminal repeat promoter by bridging promoter-bound factors and the Tat-P-TEFb complex.AMPK regulates metabolic actions of glucocorticoids by phosphorylating the glucocorticoid receptor through p38 MAPKMolecular pathways in virus-induced cytokine production.Human immunodeficiency virus type 1 (HIV-1) accessory protein Vpr induces transcription of the HIV-1 and glucocorticoid-responsive promoters by binding directly to p300/CBP coactivators.The progestin-only contraceptive medroxyprogesterone acetate, but not norethisterone acetate, enhances HIV-1 Vpr-mediated apoptosis in human CD4+ T cells through the glucocorticoid receptor.HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic interventionImpact of antiretroviral therapy on lipid metabolism of human immunodeficiency virus-infected patients: Old and new drugs.Viral mechanisms of adipose dysfunction: lessons from HIV-1 VprZNF764 haploinsufficiency may explain partial glucocorticoid, androgen, and thyroid hormone resistance associated with 16p11.2 microdeletion.G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus.Phase I/II trial of the anti-HIV activity of mifepristone in HIV-infected subjects ACTG 5200CRTC2 Is a Coactivator of GR and Couples GR and CREB in the Regulation of Hepatic Gluconeogenesis.Human immunodeficiency virus (HIV)-1 viral protein R suppresses transcriptional activity of peroxisome proliferator-activated receptor {gamma} and inhibits adipocyte differentiation: implications for HIV-associated lipodystrophy.Stress system activity, innate and T helper cytokines, and susceptibility to immune-related diseases.Activated glucocorticoid receptor interacts with the INHAT component Set/TAF-Ibeta and releases it from a glucocorticoid-responsive gene promoter, relieving repression: implications for the pathogenesis of glucocorticoid resistance in acute undifferBenefits of leptin therapy in HIV patients.Pathogenesis and treatment of HIV lipohypertrophyAltered relationship of plasma triglycerides to HDL cholesterol in patients with HIV/HAART-associated dyslipidemia: further evidence for a unique form of metabolic syndrome in HIV patients.Cortisol patterns are associated with T cell activation in HIV
P2860
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P2860
The HIV-1 virion-associated protein vpr is a coactivator of the human glucocorticoid receptor.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
The HIV-1 virion-associated pr ...... human glucocorticoid receptor.
@ast
The HIV-1 virion-associated pr ...... human glucocorticoid receptor.
@en
type
label
The HIV-1 virion-associated pr ...... human glucocorticoid receptor.
@ast
The HIV-1 virion-associated pr ...... human glucocorticoid receptor.
@en
prefLabel
The HIV-1 virion-associated pr ...... human glucocorticoid receptor.
@ast
The HIV-1 virion-associated pr ...... human glucocorticoid receptor.
@en
P2093
P2860
P356
P1476
The HIV-1 virion-associated pr ...... human glucocorticoid receptor.
@en
P2093
P2860
P356
10.1084/JEM.189.1.51
P407
P577
1999-01-01T00:00:00Z