A conserved dileucine-containing motif in p6(gag) governs the particle association of Vpx and Vpr of simian immunodeficiency viruses SIV(mac) and SIV(agm)
about
SAMHD1-deficient CD14+ cells from individuals with Aicardi-Goutières syndrome are highly susceptible to HIV-1 infectionNew insights into an X-traordinary viral proteinThe Vpr protein from HIV-1: distinct roles along the viral life cycleThe human immunodeficiency virus type 2 Vpx protein usurps the CUL4A-DDB1 DCAF1 ubiquitin ligase to overcome a postentry block in macrophage infectionVpx is critical for reverse transcription of the human immunodeficiency virus type 2 genome in macrophagesHIV Genome-Wide Protein Associations: a Review of 30 Years of ResearchEvolutionary modeling of rate shifts reveals specificity determinants in HIV-1 subtypesCharacterization of a novel type of HIV-1 particle assembly inhibitor using a quantitative luciferase-Vpr packaging-based assayFluorescent image analysis of HIV-1 and HIV-2 uncoating kinetics in the presence of old world monkey TRIM5αThe inhibition of assembly of HIV-1 virus-like particles by 3-O-(3',3'-dimethylsuccinyl) betulinic acid (DSB) is counteracted by Vif and requires its Zinc-binding domain.Isolation of human immunodeficiency virus type 1 cores: retention of Vpr in the absence of p6(gag).Human immunodeficiency virus type 1 Vpr protein is incorporated into the virion in significantly smaller amounts than gag and is phosphorylated in infected cellsFunctional analysis of the simian immunodeficiency virus Vpx protein: identification of packaging determinants and a novel nuclear targeting domain.Partial restoration of replication of simian immunodeficiency virus by point mutations in either the dimerization initiation site (DIS) or Gag region after deletion mutagenesis within the DIS.Clathrin facilitates the morphogenesis of retrovirus particles.The Vpx lentiviral accessory protein targets SAMHD1 for degradation in the nucleus.Simian immunodeficiency virus Vpx is imported into the nucleus via importin alpha-dependent and -independent pathwaysIdentification of critical regions in human SAMHD1 required for nuclear localization and Vpx-mediated degradationHuman immunodeficiency virus type 1 and related primate lentiviruses engage clathrin through Gag-Pol or Gag.Human immunodeficiency virus type 1 modified to package Simian immunodeficiency virus Vpx efficiently infects macrophages and dendritic cells.Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon.SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells.Lentiviral Gag assembly analyzed through the functional characterization of chimeric simian immunodeficiency viruses expressing different domains of the feline immunodeficiency virus capsid protein.Molecular characterization of a new mosaic Simian Immunodeficiency Virus in a naturally infected tantalus monkey (Chlorocebus tantalus) from Cameroon: a challenge to the virus-host co-evolution of SIVagm in African green monkeys.Evidence for Vpr-dependent HIV-1 replication in human CD4+ CEM.NKR T-cells.Adaptation to the interferon-induced antiviral state by human and simian immunodeficiency virusesThe efficiency of Vpx-mediated SAMHD1 antagonism does not correlate with the potency of viral control in HIV-2-infected individuals.Restriction of diverse retroviruses by SAMHD1.Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells.HIV-1 Vpr: mechanisms of G2 arrest and apoptosis.Inhibition of CUL4A Neddylation causes a reversible block to SAMHD1-mediated restriction of HIV-1TLR7/8 agonist induces a post-entry SAMHD1-independent block to HIV-1 infection of monocytes.HIV-2 Vpx protein interacts with interferon regulatory factor 5 (IRF5) and inhibits its function.Limelight on two HIV/SIV accessory proteins in macrophage infection: is Vpx overshadowing Vpr?Evidence for an activation domain at the amino terminus of simian immunodeficiency virus Vpx.Inhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase AssemblyDegradation of SAMHD1 by Vpx Is Independent of Uncoating.Proline 35 of human immunodeficiency virus type 1 (HIV-1) Vpr regulates the integrity of the N-terminal helix and the incorporation of Vpr into virus particles and supports the replication of R5-tropic HIV-1 in human lymphoid tissue ex vivo.The C-terminal proline-rich tail of human immunodeficiency virus type 2 Vpx is necessary for nuclear localization of the viral preintegration complex in nondividing cells.A cellular restriction dictates the permissivity of nondividing monocytes/macrophages to lentivirus and gammaretrovirus infection.
P2860
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P2860
A conserved dileucine-containing motif in p6(gag) governs the particle association of Vpx and Vpr of simian immunodeficiency viruses SIV(mac) and SIV(agm)
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A conserved dileucine-containi ...... viruses SIV(mac) and SIV(agm)
@ast
A conserved dileucine-containi ...... viruses SIV(mac) and SIV(agm)
@en
type
label
A conserved dileucine-containi ...... viruses SIV(mac) and SIV(agm)
@ast
A conserved dileucine-containi ...... viruses SIV(mac) and SIV(agm)
@en
prefLabel
A conserved dileucine-containi ...... viruses SIV(mac) and SIV(agm)
@ast
A conserved dileucine-containi ...... viruses SIV(mac) and SIV(agm)
@en
P2093
P2860
P1433
P1476
A conserved dileucine-containi ...... viruses SIV(mac) and SIV(agm)
@en
P2093
A A Bukovsky
H G Göttlinger
M A Accola
P2860
P304
P577
1999-12-01T00:00:00Z