The central globular domain of the nucleocapsid protein of human immunodeficiency virus type 1 is critical for virion structure and infectivity
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Inhibition of HIV-1 replication by a bis-thiadiazolbenzene-1,2-diamine that chelates zinc ions from retroviral nucleocapsid zinc fingersQuantitative Characterization of Configurational Space Sampled by HIV-1 Nucleocapsid Using Solution NMR, X-ray Scattering and Protein EngineeringA single zinc finger optimizes the DNA interactions of the nucleocapsid protein of the yeast retrotransposon Ty3.Multiple effects of an anti-human immunodeficiency virus nucleocapsid inhibitor on virus morphology and replication.Human Polycomb group EED protein negatively affects HIV-1 assembly and release.Interaction with the p6 domain of the gag precursor mediates incorporation into virions of Vpr and Vpx proteins from primate lentivirusesDistinct nucleic acid interaction properties of HIV-1 nucleocapsid protein precursor NCp15 explain reduced viral infectivity.Basic residues in human immunodeficiency virus type 1 nucleocapsid promote virion assembly via interaction with RNA.Rescue of multiple viral functions by a second-site suppressor of a human immunodeficiency virus type 1 nucleocapsid mutation.The gag domains required for avian retroviral RNA encapsidation determined by using two independent assays.Alteration of zinc-binding residues of simian immunodeficiency virus p8(NC) results in subtle differences in gag processing and virion maturation associated with degradative loss of mutant NC.The yeast Ty3 retrotransposon contains a 5'-3' bipartite primer-binding site and encodes nucleocapsid protein NCp9 functionally homologous to HIV-1 NCp7Dynamics of linker residues modulate the nucleic acid binding properties of the HIV-1 nucleocapsid protein zinc fingersp6Gag is required for particle production from full-length human immunodeficiency virus type 1 molecular clones expressing proteaseImportance of basic residues in binding of rous sarcoma virus nucleocapsid to the RNA packaging signal.A selective screen reveals discrete functional domains in Drosophila Nanos.Role of HIV-1 RNA and protein determinants for the selective packaging of spliced and unspliced viral RNA and host U6 and 7SL RNA in virus particlesThe zinc finger of nucleocapsid protein of Friend murine leukemia virus is critical for proviral DNA synthesis in vivoCharged amino acid residues of human immunodeficiency virus type 1 nucleocapsid p7 protein involved in RNA packaging and infectivity.Determinants of the human immunodeficiency virus type 1 p15NC-RNA interaction that affect enhanced cleavage by the viral protease.Effects of nucleocapsid mutations on human immunodeficiency virus assembly and RNA encapsidationThe cytopathicity of a simian immunodeficiency virus Mne variant is determined by mutations in Gag and Env.Live-cell observation of cytosolic HIV-1 assembly onset reveals RNA-interacting Gag oligomers.Intracellular HIV-1 Gag localization is impaired by mutations in the nucleocapsid zinc fingers.Identification and characterization of a new type of inhibitor against the human immunodeficiency virus type-1 nucleocapsid protein.Virion packaging determinants and reverse transcription of SRP RNA in HIV-1 particles.Aqueous extracts from peppermint, sage and lemon balm leaves display potent anti-HIV-1 activity by increasing the virion density.Human immunodeficiency virus type 1 Vif protein binds to the Pr55Gag precursor.Nucleocapsid protein function in early infection processes.Properties and functions of the nucleocapsid protein in virus assembly.The effect of mutations in the HIV-1 nucleocapsid protein on strand transfer in cell-free reverse transcription reactionsThe role of nucleocapsid and U5 stem/A-rich loop sequences in tRNA(3Lys) genomic placement and initiation of reverse transcription in human immunodeficiency virus type 1.Role of the N-terminal zinc finger of human immunodeficiency virus type 1 nucleocapsid protein in virus structure and replication.The I domain is required for efficient plasma membrane binding of human immunodeficiency virus type 1 Pr55Gag.Mutations in the primer grip of human immunodeficiency virus type 1 reverse transcriptase impair proviral DNA synthesis and virion maturation.Role of RNA in facilitating Gag/Gag-Pol interaction.A dual role of the putative RNA dimerization initiation site of human immunodeficiency virus type 1 in genomic RNA packaging and proviral DNA synthesisEffect of mutations in the nucleocapsid protein (NCp7) upon Pr160(gag-pol) and tRNA(Lys) incorporation into human immunodeficiency virus type 1.Mutations in the N-terminal domain of human immunodeficiency virus type 1 nucleocapsid protein affect virion core structure and proviral DNA synthesis.The conserved N-terminal basic residues and zinc-finger motifs of HIV-1 nucleocapsid restrict the viral cDNA synthesis during virus formation and maturation.
P2860
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P2860
The central globular domain of the nucleocapsid protein of human immunodeficiency virus type 1 is critical for virion structure and infectivity
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
The central globular domain of ...... rion structure and infectivity
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The central globular domain of ...... rion structure and infectivity
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The central globular domain of ...... rion structure and infectivity
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The central globular domain of ...... rion structure and infectivity
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The central globular domain of ...... rion structure and infectivity
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The central globular domain of ...... rion structure and infectivity
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P2093
P2860
P1433
P1476
The central globular domain of ...... rion structure and infectivity
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P2093
P2860
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1995-03-01T00:00:00Z