T cell signaling abnormalities contribute to aberrant immune cell function and autoimmunity.
about
A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70Putting together the autoimmunity puzzle.Pathways leading to an immunological disease: systemic lupus erythematosus.Tanshinone IIA attenuates renal damage in STZ-induced diabetic rats via inhibiting oxidative stress and inflammation.Pin1-Targeted Therapy for Systemic Lupus ErythematosusT Cell Transcriptomes Describe Patient Subtypes in Systemic Lupus Erythematosus.Ethnicity-specific epigenetic variation in naïve CD4+ T cells and the susceptibility to autoimmunity.Glucose Oxidation Is Critical for CD4+ T Cell Activation in a Mouse Model of Systemic Lupus Erythematosus.Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus.Decreased SAP Expression in T Cells from Patients with Systemic Lupus Erythematosus Contributes to Early Signaling Abnormalities and Reduced IL-2 Production.ICER is requisite for Th17 differentiation.Metabolic Factors that Contribute to Lupus PathogenesisElevated serum autoantibodies against co-inhibitory PD-1 facilitate T cell proliferation and correlate with disease activity in new-onset systemic lupus erythematosus patients.Decreased ex vivo production of interferon-gamma is associated with severity and poor prognosis in patients with lupus.Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies.T cells and IL-17 in lupus nephritis.The Role of STAT Signaling Pathways in the Pathogenesis of Systemic Lupus Erythematosus.T cells in Systemic Lupus Erythematosus.Regulation of T cell signalling by membrane lipids.Low-Dose IL-2 in the Treatment of Lupus.miRNA-451a Targets IFN Regulatory Factor 8 for the Progression of Systemic Lupus Erythematosus.T cells and autoimmune kidney disease.Immunometabolism in systemic lupus erythematosus.Pathogenesis of Human Systemic Lupus Erythematosus: A Cellular Perspective.ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings.Epigenetic Reprogramming in Naive CD4+ T Cells Favoring T Cell Activation and Non-Th1 Effector T Cell Immune Response as an Early Event in Lupus FlaresSelective Loss of Signaling Lymphocytic Activation Molecule Family Member 4-Positive CD8+ T Cells Contributes to the Decreased Cytotoxic Cell Activity in Systemic Lupus Erythematosus.Altered microRNAs expression in T cells of patients with SLE involved in the lack of vitamin D.The role of CaMK4 in immune responses.BPTF Is Essential for T Cell Homeostasis and Function.Transcription factors early growth response gene (Egr) 2 and 3 control inflammatory responses of tolerant T cells.TCR Signal Strength Regulates Akt Substrate Specificity To Induce Alternate Murine Th and T Regulatory Cell Differentiation Programs.Core Fucosylation of the T Cell Receptor Is Required for T Cell Activation.Ionic CD3-Lck interaction regulates the initiation of T-cell receptor signaling.Recent developments in systemic lupus erythematosus pathogenesis and applications for therapy.The Potential Role of Trained Immunity in Autoimmune and Autoinflammatory Disorders.Downregulation of CD3ζ in NK Cells from Systemic Lupus Erythematosus Patients Confers a Proinflammatory Phenotype.A Distinct T Follicular Helper Cell Subset Infiltrates the Brain in Murine Neuropsychiatric Lupus.Systemic lupus erythematosus in 2015: Cellular and metabolic requirements of effector T cells.Circulating hsa-miR-30e-5p, hsa-miR-92a-3p, and hsa-miR-223-3p may be novel biomarkers in systemic lupus erythematosus.
P2860
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P2860
T cell signaling abnormalities contribute to aberrant immune cell function and autoimmunity.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
T cell signaling abnormalities ...... ell function and autoimmunity.
@ast
T cell signaling abnormalities ...... ell function and autoimmunity.
@en
type
label
T cell signaling abnormalities ...... ell function and autoimmunity.
@ast
T cell signaling abnormalities ...... ell function and autoimmunity.
@en
prefLabel
T cell signaling abnormalities ...... ell function and autoimmunity.
@ast
T cell signaling abnormalities ...... ell function and autoimmunity.
@en
P2860
P356
P1476
T cell signaling abnormalities ...... ell function and autoimmunity.
@en
P2093
George C Tsokos
Vaishali R Moulton
P2860
P304
P356
10.1172/JCI78087
P407
P577
2015-05-11T00:00:00Z