Glutathione s-transferase omega 1 activity is sufficient to suppress neurodegeneration in a Drosophila model of Parkinson disease - Wikidata - awgldk - TriplyDB

Glutathione s-transferase omega 1 activity is sufficient to suppress neurodegeneration in a Drosophila model of Parkinson disease

Glutathione s-transferase omega 1 activity is sufficient to suppress neurodegeneration in a Drosophila model of Parkinson disease

http://www.wikidata.org/entity/Q35839001

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Perturbations in dopamine synthesis lead to discrete physiological effects and impact oxidative stress response in Drosophila.Structural modelling and molecular characterization of omega-class glutathione S-transferase 2 from Drosophila melanogaster.The cellular redox environment alters antigen presentation A Halloween gene noppera-bo encodes a glutathione S-transferase essential for ecdysteroid biosynthesis via regulating the behaviour of cholesterol in Drosophila.Vesicular signalling and immune modulation as hedonic fingerprints: proteomic profiling in the chronic mild stress depression model.Orthologs of human disease associated genes and RNAi analysis of silencing insulin receptor gene in Bombyx mori.Homozygous splice mutation in CWF19L1 in a Turkish family with recessive ataxia syndrome Micro-plasticity of genomes as illustrated by the evolution of glutathione transferases in 12 Drosophila species.GSTP1 and GSTO1 single nucleotide polymorphisms and the response of bladder cancer patients to intravesical chemotherapy.A novel Omega-class glutathione S-transferase gene in Apis cerana cerana: molecular characterisation of GSTO2 and its protective effects in oxidative stress.Glutathione metabolism and Parkinson's disease.Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor Structure, function and disease relevance of Omega-class glutathione transferases.Quantification and visualization of glutathione S-transferase omega 1 in cells using inductively coupled plasma mass spectrometry (ICP-MS) and fluorescence microscopy.Interaction of Omega, Sigma, and Theta glutathione transferases with p38b mitogen-activated protein kinase from the fruit fly, Drosophila melanogaster.Resveratrol Modulation of Protein Expression in parkin-Mutant Human Skin Fibroblasts: A Proteomic Approach.A Simple One-step Dissection Protocol for Whole-mount Preparation of Adult Drosophila Brains.Omega Class Glutathione S-Transferase: Antioxidant Enzyme in Pathogenesis of Neurodegenerative Diseases.Protein Glutathionylation in the Pathogenesis of Neurodegenerative Diseases.Analysis of dopaminergic neuronal dysfunction in genetic and toxin-induced models of Parkinson's disease in Drosophila.

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P2860

Glutathione s-transferase omega 1 activity is sufficient to suppress neurodegeneration in a Drosophila model of Parkinson disease

http://www.wikidata.org/entity/Q35839001

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Glutathione s-transferase omeg ...... ila model of Parkinson disease

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Journal of Biological Chemistry

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Glutathione s-transferase omeg ...... ila model of Parkinson disease

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Heuijong Kim

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Jaekwang Kim

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Jeongbin Yim

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Kiyoung Kim

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Song-Hee Kim

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P2860

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

The glutathione transferase structural family includes a nuclear chloride channel and a ryanodine receptor calcium release channel modulator

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling

Mitochondrial ATP synthase deficiency due to a mutation in the ATP5E gene for the F1 epsilon subunit

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily

Identification, characterization, and crystal structure of the Omega class glutathione transferases

Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease

Parkin binds to alpha/beta tubulin and increases their ubiquitination and degradation

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6628-6641

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scholarly article

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10.1074/JBC.M111.291179

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9

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51983885

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22219196

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Parkinson's disease

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3307323

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