Lysophosphatidic acid production and action: validated targets in cancer? - Wikidata - awgldk - TriplyDB

Lysophosphatidic acid production and action: validated targets in cancer?

Lysophosphatidic acid production and action: validated targets in cancer?

http://www.wikidata.org/entity/Q35839002

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L-histidine inhibits production of lysophosphatidic acid by the tumor-associated cytokine, autotaxin Synthesis and biological evaluation of phosphonate derivatives as autotaxin (ATX) inhibitors.Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis.Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells.Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis.Inhibition of tumor growth and angiogenesis by a lysophosphatidic acid antagonist in an engineered three-dimensional lung cancer xenograft model.Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases.ATX-LPA receptor axis in inflammation and cancer.Emerging function of mTORC2 as a core regulator in glioblastoma: metabolic reprogramming and drug resistance.Reduced expression of autotaxin predicts survival in uveal melanoma.Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo Synthesis, pharmacology, and cell biology of sn-2-aminooxy analogues of lysophosphatidic acid.Monitoring the health to disease continuum with global metabolic profiling and systems biology.Mass spectrometry images acylcarnitines, phosphatidylcholines, and sphingomyelin in MDA-MB-231 breast tumor models.Fluorogenic phospholipid substrate to detect lysophospholipase D/autotaxin activity Therapeutic potential of autotaxin/lysophospholipase d inhibitors.Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells Evaluating dual activity LPA receptor pan-antagonist/autotaxin inhibitors as anti-cancer agents in vivo using engineered human tumors Roles of LPA in ovarian cancer development and progression.Towards novel radiosensitizing agents: the role of cytosolic PLA2α in combined modality cancer therapy.Molecular targeted therapy in ovarian cancer: what is on the horizon?A targeted mass spectrometric analysis of phosphatidylinositol phosphate species.Alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA Lysophosphatidic acid receptor inhibition as a new multipronged treatment for rheumatoid arthritis.Endophilin and CtBP/BARS are not acyl transferases in endocytosis or Golgi fission.Immunohistochemical detection of autotaxin (ATX)/lysophospholipase D (lysoPLD) in submucosal invasive colorectal cancer.Blocking LPA-dependent signaling increases ovarian cancer cell death in response to chemotherapy.Lysophosphatidic acid receptor 1 suppression sensitizes rheumatoid fibroblast-like synoviocytes to tumor necrosis factor-induced apoptosis.Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals.

P2860

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P2860

Lysophosphatidic acid production and action: validated targets in cancer?

http://www.wikidata.org/entity/Q35839002

description

2004 nî lūn-bûn

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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2004年论文

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2004年论文

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name

Lysophosphatidic acid production and action: validated targets in cancer?

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Lysophosphatidic acid production and action: validated targets in cancer?

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Lysophosphatidic acid production and action: validated targets in cancer?

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Lysophosphatidic acid production and action: validated targets in cancer?

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Lysophosphatidic acid production and action: validated targets in cancer?

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Lysophosphatidic acid production and action: validated targets in cancer?

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P1433

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P1433

Journal of Cellular Biochemistry

P1476

Lysophosphatidic acid production and action: validated targets in cancer?

@en

P2093

Colin G Ferguson

http://www.w3.org/2001/XMLSchema#string

Eric Jonasch

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Glenn D Prestwich

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Gordon B Mills

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Janos Tanyi

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Jinsong Liu

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John Lahad

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Ken Aldape

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Makiko Umezu-Goto

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Robyn D James

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1115-1140

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scholarly article

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10.1002/JCB.20113

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6

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92

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2004-08-01T00:00:00Z

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15258897

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