Biotransformation of the antiretroviral drug etravirine: metabolite identification, reaction phenotyping, and characterization of autoinduction of cytochrome P450-dependent metabolism
about
Interaction between Darunavir and Etravirine Is Partly Mediated by CYP3A5 PolymorphismOptimization of the antiviral potency and lipophilicity of halogenated 2,6-diarylpyridinamines as a novel class of HIV-1 NNRTIS.Impact of antiretroviral therapy on lipid metabolism of human immunodeficiency virus-infected patients: Old and new drugs.Physiologically Based Pharmacokinetic Modelling to Inform Development of Intramuscular Long-Acting Nanoformulations for HIV.Etravirine Pharmacokinetics in HIV-Infected Pregnant Women.Dissimilarities in the metabolism of antiretroviral drugs used in HIV pre-exposure prophylaxis in colon and vagina tissues.Human biotransformation of the nonnucleoside reverse transcriptase inhibitor rilpivirine and a cross-species metabolism comparison.Potential effect of pharmacogenetics on maternal, fetal and infant antiretroviral drug exposure during pregnancy and breastfeeding.Clinical pharmacokinetic drug interactions associated with artemisinin derivatives and HIV-antivirals.Use of a physiologically based pharmacokinetic model to simulate drug-drug interactions between antineoplastic and antiretroviral drugs.Evaluation of Concomitant Antiretrovirals and CYP2C9/CYP2C19 Polymorphisms on the Pharmacokinetics of Etravirine.Metabolism of F18, a Derivative of Calanolide A, in Human Liver Microsomes and Cytosol.Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Relationships of Etravirine in HIV-1-Infected, Treatment-Experienced Children and Adolescents in PIANO.Liver toxicity and risk of discontinuation in HIV/hepatitis C virus-coinfected patients receiving an etravirine-containing antiretroviral regimen: influence of liver fibrosis.The effect of single- and multiple-dose etravirine on a drug cocktail of representative cytochrome P450 probes and digoxin in healthy subjects.Clinical risks of St John's Wort (Hypericum perforatum) co-administration.Identification of cytochrome P450s involved in the metabolism of 6-benzyl-1-benzyloxymethyl-5-iodouracil (W-1) using human recombinant enzymes and rat liver microsomes in vitro.Pharmacokinetics of darunavir/cobicistat and etravirine alone and co-administered in HIV-infected patients.
P2860
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P2860
Biotransformation of the antiretroviral drug etravirine: metabolite identification, reaction phenotyping, and characterization of autoinduction of cytochrome P450-dependent metabolism
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Biotransformation of the antir ...... rome P450-dependent metabolism
@ast
Biotransformation of the antir ...... rome P450-dependent metabolism
@en
type
label
Biotransformation of the antir ...... rome P450-dependent metabolism
@ast
Biotransformation of the antir ...... rome P450-dependent metabolism
@en
prefLabel
Biotransformation of the antir ...... rome P450-dependent metabolism
@ast
Biotransformation of the antir ...... rome P450-dependent metabolism
@en
P2860
P356
P1476
Biotransformation of the antir ...... rome P450-dependent metabolism
@en
P2093
Lindsay J Yanakakis
Namandjé N Bumpus
P2860
P304
P356
10.1124/DMD.111.044404
P577
2012-01-23T00:00:00Z