Abnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS) - Wikidata - awgldk - TriplyDB

Abnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS)

Abnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS)

http://www.wikidata.org/entity/Q35849941

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Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee Lighting the fires within: the cell biology of autoinflammatory diseases Beyond the NLRP3 inflammasome: autoinflammatory diseases reach adolescence Involvement of the same TNFR1 residue in mendelian and multifactorial inflammatory disorders.A common mechanism of PLP/DM20 misfolding causes cysteine-mediated endoplasmic reticulum retention in oligodendrocytes and Pelizaeus-Merzbacher disease.Role of tumour necrosis factor (TNF)-α and TNFRSF1A R92Q mutation in the pathogenesis of TNF receptor-associated periodic syndrome and multiple sclerosis.Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome.IL-1 blockade in autoinflammatory syndromes.Monogenic autoinflammatory diseases: new insights into clinical aspects and pathogenesis.Pathogenesis of familial periodic fever syndromes or hereditary autoinflammatory syndromes.Falling into TRAPS--receptor misfolding in the TNF receptor 1-associated periodic fever syndrome Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)A pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS)Long-term clinical profile of children with the low-penetrance R92Q mutation of the TNFRSF1A gene Tumour necrosis factor receptor trafficking dysfunction opens the TRAPS door to pro-inflammatory cytokine secretion.The novel S59P mutation in the TNFRSF1A gene identified in an adult onset TNF receptor associated periodic syndrome (TRAPS) constitutively activates NF-κB pathway Sensors of the innate immune system: their link to rheumatic diseases.Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling.The spectrum of autoinflammatory diseases: recent bench to bedside observations Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells Autoinflammatory disease reloaded: a clinical perspective.Autoinflammatory diseases.Autoinflammatory diseases: an update of clinical and genetic aspects.Genetic defects of apoptosis and primary immunodeficiency.Monogenic autoinflammatory diseases: concept and clinical manifestations.The spectrum of monogenic autoinflammatory syndromes: understanding disease mechanisms and use of targeted therapies.Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus.Efficacy of etanercept in the tumor necrosis factor receptor-associated periodic syndrome: a prospective, open-label, dose-escalation study.Monogenic autoinflammatory diseases: disorders of amplified danger sensing and cytokine dysregulation.Canakinumab reverses overexpression of inflammatory response genes in tumour necrosis factor receptor-associated periodic syndrome.Setting up TRAPS.Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) in Japan: a review of the literature.Tumor necrosis factor receptor-associated periodic syndrome as a model linking autophagy and inflammation in protein aggregation diseases.Monogenic autoinflammatory diseases.Key facts and hot spots on tumor necrosis factor receptor-associated periodic syndrome.The inflammasome and IL-1β: implications for the treatment of inflammatory diseases.Protein misfolding and dysregulated protein homeostasis in autoinflammatory diseases and beyond.Canakinumab for the treatment of TNF-receptor associated periodic syndrome.Tumour necrosis factor receptor I blockade shows that TNF-dependent and TNF-independent mechanisms synergise in TNF receptor associated periodic syndrome.

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P2860

Abnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS)

http://www.wikidata.org/entity/Q35849941

description

2006 nî lūn-bûn

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2006年論文

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2006年論文

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2006年论文

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2006年论文

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name

Abnormal disulfide-linked olig ...... eriodic fever syndrome (TRAPS)

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Abnormal disulfide-linked olig ...... eriodic fever syndrome (TRAPS)

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Abnormal disulfide-linked olig ...... eriodic fever syndrome (TRAPS)

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Abnormal disulfide-linked olig ...... eriodic fever syndrome (TRAPS)

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Adrian A Lobito

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Adrianna J Jackson

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Daniel L Kastner

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Fiona C Kimberley

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Hirsh Komarow

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Jagan R Muppidi

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Keith M Hull

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Richard M Siegel

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P2860

Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

Heterogeneity among patients with tumor necrosis factor receptor-associated periodic syndrome phenotypes

The tumor-necrosis-factor receptor-associated periodic syndrome: new mutations in TNFRSF1A, ancestral origins, genotype-phenotype studies, and evidence for further genetic heterogeneity of periodic fevers.

Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation

The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity

Aggresomes: a cellular response to misfolded proteins

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Gavin R Screaton

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7096224

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16684962

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1895878

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