Directed integration of viral DNA mediated by fusion proteins consisting of human immunodeficiency virus type 1 integrase and Escherichia coli LexA protein.
about
Gene therapy for severe combined immunodeficiency: are we there yet?Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferencesRetroviral vectors and transposons for stable gene therapy: advances, current challenges and perspectivesDriving DNA transposition by lentiviral protein transductionRequirement for integrase during reverse transcription of human immunodeficiency virus type 1 and the effect of cysteine mutations of integrase on its interactions with reverse transcriptase.Integrase-specific enhancement and suppression of retroviral DNA integration by compacted chromatin structure in vitroRevealing domain structure through linker-scanning analysis of the murine leukemia virus (MuLV) RNase H and MuLV and human immunodeficiency virus type 1 integrase proteinsIntegration site selection by retroviral vectors: molecular mechanism and clinical consequences.Cancer risk at low doses of ionizing radiation: artificial neural networks inference from atomic bomb survivors.Irreversible inhibition of human immunodeficiency virus type 1 integrase by dicaffeoylquinic acids.Mapping viral DNA specificity to the central region of integrase by using functional human immunodeficiency virus type 1/visna virus chimeric proteinsA chimeric Ty3/Moloney murine leukemia virus integrase protein is active in vivo.Integrase-lexA fusion proteins incorporated into human immunodeficiency virus type 1 that contains a catalytically inactive integrase gene are functional to mediate integrationUse of patient-derived human immunodeficiency virus type 1 integrases to identify a protein residue that affects target site selectionMethods for integration site distribution analyses in animal cell genomesHuman immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cellsAn amino acid in the central catalytic domain of three retroviral integrases that affects target site selection in nonviral DNA.Integration by design.Controlling integration specificity of a yeast retrotransposonCurrent advances in retroviral gene therapy.Retroviral integration site selection.Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein E2C direct integration of viral DNA into specific sitesRecognition of triple-helical DNA structures by transposon Tn7.Site-directed transposon integration in human cells.Reversion of a human immunodeficiency virus type 1 integrase mutant at a second site restores enzyme function and virus infectivityTethering human immunodeficiency virus type 1 preintegration complexes to target DNA promotes integration at nearby sites.Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase.Molecular mechanisms by which human immunodeficiency virus type 1 integrase stimulates the early steps of reverse transcription.Retargeting sleeping beauty transposon insertions by engineered zinc finger DNA-binding domains.Sites of retroviral DNA integration: From basic research to clinical applicationsSite-specific integration of retroviral DNA in human cells using fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc-finger protein E2C.Biochemical and random mutagenesis analysis of the region carrying the catalytic E152 amino acid of HIV-1 integraseTargeted genome editing by lentiviral protein transduction of zinc-finger and TAL-effector nucleasesViral hybrid vectors for somatic integration - are they the better solution?Precise targeted integration by a chimaeric transposase zinc-finger fusion protein.Characterization of a late entry event in the replication cycle of human immunodeficiency virus type 2rDNA-directed integration by an HIV-1 integrase--I-PpoI fusion proteinRelative Comparison of Catalytic Characteristics of Human Foamy Virus and HIV-1 Integrases.Mechanistic and pharmacological analyses of HIV-1 integration.Design and Potential of Non-Integrating Lentiviral Vectors.
P2860
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P2860
Directed integration of viral DNA mediated by fusion proteins consisting of human immunodeficiency virus type 1 integrase and Escherichia coli LexA protein.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Directed integration of viral ...... Escherichia coli LexA protein.
@ast
Directed integration of viral ...... Escherichia coli LexA protein.
@en
type
label
Directed integration of viral ...... Escherichia coli LexA protein.
@ast
Directed integration of viral ...... Escherichia coli LexA protein.
@en
prefLabel
Directed integration of viral ...... Escherichia coli LexA protein.
@ast
Directed integration of viral ...... Escherichia coli LexA protein.
@en
P2860
P1433
P1476
Directed integration of viral ...... Escherichia coli LexA protein.
@en
P2093
P2860
P407
P577
1996-01-01T00:00:00Z