about
A transposon and transposase system for human applicationThe Sleeping Beauty transposon system: a non-viral vector for gene therapyPreferential delivery of the Sleeping Beauty transposon system to livers of mice by hydrodynamic injectionEnabling functional genomics with genome engineeringA bend, flip and trap mechanism for transposon integrationCRISPR-Cas9 System as a Versatile Tool for Genome Engineering in Human CellsDriving DNA transposition by lentiviral protein transductionComparative analysis of the recently discovered hAT transposon TcBuster in human cellsGenome-wide target profiling of piggyBac and Tol2 in HEK 293: pros and cons for gene discovery and gene therapyPostintegrative gene silencing within the Sleeping Beauty transposition systemZFN, TALEN, and CRISPR/Cas-based methods for genome engineeringEnzymatic engineering of the porcine genome with transposons and recombinases.Modular system for the construction of zinc-finger libraries and proteins.High-level genomic integration, epigenetic changes, and expression of sleeping beauty transgeneMutational derivatives of PhiC31 integrase with increased efficiency and specificity.Hybrid lentivirus-transposon vectors with a random integration profile in human cells.piggyBac transposon-mediated long-term gene expression in mice.Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies.Translating Sleeping Beauty transposition into cellular therapies: victories and challenges.Gene transfer efficiency and genome-wide integration profiling of Sleeping Beauty, Tol2, and piggyBac transposons in human primary T cellsLong-term reduction of jaundice in Gunn rats by nonviral liver-targeted delivery of Sleeping Beauty transposonRNA interference is responsible for reduction of transgene expression after Sleeping Beauty transposase mediated somatic integration.Herpes simplex virus/Sleeping Beauty vector-based embryonic gene transfer using the HSB5 mutant: loss of apparent transposition hyperactivity in vivoHyperactive sleeping beauty transposase enables persistent phenotypic correction in mice and a canine model for hemophilia B.A superfamily of DNA transposons targeting multicopy small RNA genes.Hybrid adeno-associated viral vectors utilizing transposase-mediated somatic integration for stable transgene expression in human cells.PiggyBac transposon-mediated, reversible gene transfer in human embryonic stem cellsComparative genomic integration profiling of Sleeping Beauty transposons mobilized with high efficacy from integrase-defective lentiviral vectors in primary human cells.Targeted plasmid integration into the human genome by an engineered zinc-finger recombinaseThe folding of the specific DNA recognition subdomain of the sleeping beauty transposase is temperature-dependent and is required for its binding to the transposon DNA.Hyperactive piggyBac gene transfer in human cells and in vivo.Chimeric piggyBac transposases for genomic targeting in human cellsRetargeting transposon insertions by the adeno-associated virus Rep protein.Retargeting sleeping beauty transposon insertions by engineered zinc finger DNA-binding domains.Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity.Efficient sleeping beauty DNA transposition from DNA minicircles.Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy.Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system.Regulated gene insertion by steroid-induced PhiC31 integrase.Active recombinant Tol2 transposase for gene transfer and gene discovery applications.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Site-directed transposon integration in human cells.
@ast
Site-directed transposon integration in human cells.
@en
type
label
Site-directed transposon integration in human cells.
@ast
Site-directed transposon integration in human cells.
@en
prefLabel
Site-directed transposon integration in human cells.
@ast
Site-directed transposon integration in human cells.
@en
P2093
P2860
P356
P1476
Site-directed transposon integration in human cells.
@en
P2093
Bassel Akache
Mark A Kay
Stephen R Yant
Yong Huang
P2860
P356
10.1093/NAR/GKM089
P407
P577
2007-03-07T00:00:00Z