Cooperative effects of the human immunodeficiency virus type 1 envelope variable loops V1 and V3 in mediating infectivity for T cells
about
Bioinformatic analysis of HIV-1 entry and pathogenesis.A novel human antibody against human immunodeficiency virus type 1 gp120 is V1, V2, and V3 loop dependent and helps delimit the epitope of the broadly neutralizing antibody immunoglobulin G1 b12.Identification of determinants on a dualtropic human immunodeficiency virus type 1 envelope glycoprotein that confer usage of CXCR4Determinants of entry cofactor utilization and tropism in a dualtropic human immunodeficiency virus type 1 primary isolate.Determinants of syncytium formation in microglia by human immunodeficiency virus type 1: role of the V1/V2 domainsDifferential CD4/CCR5 utilization, gp120 conformation, and neutralization sensitivity between envelopes from a microglia-adapted human immunodeficiency virus type 1 and its parental isolate.Distinct molecular pathways to X4 tropism for a V3-truncated human immunodeficiency virus type 1 lead to differential coreceptor interactions and sensitivity to a CXCR4 antagonist.Variations in autologous neutralization and CD4 dependence of b12 resistant HIV-1 clade C env clones obtained at different time points from antiretroviral naïve Indian patients with recent infection.Human immunodeficiency virus type 1 coreceptor switching: V1/V2 gain-of-fitness mutations compensate for V3 loss-of-fitness mutations.Partial rescue of V1V2 mutant infectivity by HIV-1 cell-cell transmission supports the domain's exceptional capacity for sequence variation.Intrapatient alterations in the human immunodeficiency virus type 1 gp120 V1V2 and V3 regions differentially modulate coreceptor usage, virus inhibition by CC/CXC chemokines, soluble CD4, and the b12 and 2G12 monoclonal antibodies.Selected amino acid mutations in HIV-1 B subtype gp41 are associated with specific gp120v₃ signatures in the regulation of co-receptor usage.Genotypic prediction of HIV-1 subtype D tropismCovariance of charged amino acids at positions 322 and 440 of HIV-1 Env contributes to coreceptor specificity of subtype B viruses, and can be used to improve the performance of V3 sequence-based coreceptor usage prediction algorithms.Role of V1V2 and other human immunodeficiency virus type 1 envelope domains in resistance to autologous neutralization during clade C infectionPopulation-based sequencing of the V3 region of env for predicting the coreceptor usage of human immunodeficiency virus type 1 quasispecies.Evolution of CXCR4-using human immunodeficiency virus type 1 SF162 is associated with two unique envelope mutations.Infection of chimpanzee peripheral blood mononuclear cells by human immunodeficiency virus type 1 requires cooperative interaction between multiple variable regions of gp120Investigation of the dynamics of the spread of human immunodeficiency virus to brain and other tissues by evolutionary analysis of sequences from the p17gag and env genesGenetic and phenotypic analyses of human immunodeficiency virus type 1 escape from a small-molecule CCR5 inhibitor.Mucosal transmissibility, disease induction and coreceptor switching of R5 SHIVSF162P3N molecular clones in rhesus macaques.R5X4 viruses are evolutionary, functional, and antigenic intermediates in the pathway of a simian-human immunodeficiency virus coreceptor switchUtilization of HIV-1 envelope V3 to identify X4- and R5-specific Tat and LTR sequence signaturesCoreceptor specificity of temporal variants of simian immunodeficiency virus Mne.Changes in the extracellular envelope glycoprotein of variants that evolve during the course of simian immunodeficiency virus SIVMne infection affect neutralizing antibody recognition, syncytium formation, and macrophage tropism but not replication,Heterogeneous spectrum of coreceptor usage among variants within a dualtropic human immunodeficiency virus type 1 primary-isolate quasispecies.Selection for neutralization resistance of the simian/human immunodeficiency virus SHIVSF33A variant in vivo by virtue of sequence changes in the extracellular envelope glycoprotein that modify N-linked glycosylation.Target cell populations of human immunodeficiency virus type 1 in peripheral blood lymphocytes with different chemokine receptors at various stages of disease progression.Human immunodeficiency virus type 1 tropism for T-lymphoid cell lines: role of the V3 loop and C4 envelope determinants.
P2860
Q27693321-EC714E46-E8C6-4C27-BC65-FEFD70C9E3DFQ31143293-6365CE9F-65AD-4875-83A5-4AE90CB27107Q33782530-6F9F8168-5135-4D5F-A57D-87D2E3D457FEQ33782925-90BCCB56-6684-43F1-970D-347C2ED4EEA0Q33796067-FCE2FB4A-FD61-41AB-829C-F5A2638CB373Q33851094-9111CA2B-6370-46AC-B73A-C298FCAEFFDAQ34055508-CAA21E65-5672-4513-AA67-006BE0CADFCDQ34203163-00E78503-2073-4AA1-B77E-9E71E6AA227DQ34301803-F9E421BB-DFD7-4009-A906-A2B246AC7DF7Q34309493-DD472610-FA91-4124-9D43-8A0384EB7F89Q34553676-C3883513-E790-4630-AFC5-B38E1AED30CEQ35052934-4697262A-8BDB-4AA1-A0CA-7B0D53A4F56DQ35137552-25E3736E-B852-4A4A-81F2-376E6B76C3BDQ35330357-124EA805-01B3-41FD-82E5-5D1DA6B1814EQ35635163-CF5569BA-2806-41EE-9CC8-192489CFC7F9Q35784605-5E69C0FB-4588-4A30-9C4A-FC2BDF2C7533Q35785164-E21C132B-C688-4D5F-BCE8-6DDDC2EDE631Q35871391-7F9F5FA7-12AB-471E-B740-06D9C835F139Q35876927-55343646-5329-4CED-A353-489665933433Q36509765-95BB89B7-D225-45E0-BDAB-4DAB53472EE7Q36608554-53D16317-D28F-44CB-AFC5-197D97382831Q36747765-E4C31586-FA63-41F7-B910-3FDA34D85DBBQ36867198-84BD6B47-965A-4E83-BE89-0C7794A848A7Q39137559-62829500-9549-4640-8FA8-CFBA1CAC2E51Q39413133-750AA55E-3592-4887-9F60-7CA1EA062E7CQ39466299-1EF133BF-666D-4CA9-AB64-D37BE243CCBBQ39594428-D8E0BD2D-DD6B-458C-9BB6-31A9850980A8Q39603455-197021AA-4C89-4FFD-A076-6A5CF6076151Q39873568-04562A24-B0A8-4881-A059-181C0CFD23CC
P2860
Cooperative effects of the human immunodeficiency virus type 1 envelope variable loops V1 and V3 in mediating infectivity for T cells
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Cooperative effects of the hum ...... iating infectivity for T cells
@ast
Cooperative effects of the hum ...... iating infectivity for T cells
@en
type
label
Cooperative effects of the hum ...... iating infectivity for T cells
@ast
Cooperative effects of the hum ...... iating infectivity for T cells
@en
prefLabel
Cooperative effects of the hum ...... iating infectivity for T cells
@ast
Cooperative effects of the hum ...... iating infectivity for T cells
@en
P2860
P1433
P1476
Cooperative effects of the hum ...... iating infectivity for T cells
@en
P2093
P2860
P304
P407
P577
1996-02-01T00:00:00Z