Determinants of syncytium formation in microglia by human immunodeficiency virus type 1: role of the V1/V2 domains
about
Bioinformatic analysis of HIV-1 entry and pathogenesis.Role of low CD4 levels in the influence of human immunodeficiency virus type 1 envelope V1 and V2 regions on entry and spread in macrophagesThe C108g epitope in the V2 domain of gp120 functions as a potent neutralization target when introduced into envelope proteins derived from human immunodeficiency virus type 1 primary isolates.Interaction with CD4 and antibodies to CD4-induced epitopes of the envelope gp120 from a microglial cell-adapted human immunodeficiency virus type 1 isolateGenetic variation and HIV-associated neurologic disease.Identification of shared populations of human immunodeficiency virus type 1 infecting microglia and tissue macrophages outside the central nervous system.Differential CD4/CCR5 utilization, gp120 conformation, and neutralization sensitivity between envelopes from a microglia-adapted human immunodeficiency virus type 1 and its parental isolate.Ability of the V3 loop of simian immunodeficiency virus to serve as a target for antibody-mediated neutralization: correlation of neutralization sensitivity, growth in macrophages, and decreased dependence on CD4The V1, V2, and V3 regions of the human immunodeficiency virus type 1 envelope differentially affect the viral phenotype in an isolate-dependent manner.Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS.Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.De novo generation of cells within human nurse macrophages and consequences following HIV-1 infection.A machine learning approach for identifying amino acid signatures in the HIV env gene predictive of dementia.A conserved determinant in the V1 loop of HIV-1 modulates the V3 loop to prime low CD4 use and macrophage infection.Lentiviral neuropathogenesis: comparative neuroinvasion, neurotropism, neurovirulence, and host neurosusceptibilityBroad-spectrum anti-human immunodeficiency virus (HIV) potential of a peptide HIV type 1 entry inhibitor.HIV-1-related central nervous system disease: current issues in pathogenesis, diagnosis, and treatment.Phenotypic Correlates of HIV-1 Macrophage Tropism.The V1-V3 region of a brain-derived HIV-1 envelope glycoprotein determines macrophage tropism, low CD4 dependence, increased fusogenicity and altered sensitivity to entry inhibitorsRole of microglial cells in selective replication of simian immunodeficiency virus genotypes in the brainBiological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enhCooperation of the V1/V2 and V3 domains of human immunodeficiency virus type 1 gp120 for interaction with the CXCR4 receptor.Variability in the human immunodeficiency virus type 1 gp120 Env protein linked to phenotype-associated changes in the V3 loop.Baseline resistance of primary human immunodeficiency virus type 1 strains to the CXCR4 inhibitor AMD3100.N-Linked Glycosylation of the HIV Type-1 gp120 Envelope Glycoprotein as a Major Determinant of CCR5 and CXCR4 Coreceptor Utilization
P2860
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P2860
Determinants of syncytium formation in microglia by human immunodeficiency virus type 1: role of the V1/V2 domains
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2000 nî lūn-bûn
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2000年の論文
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Determinants of syncytium form ...... e 1: role of the V1/V2 domains
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Determinants of syncytium form ...... e 1: role of the V1/V2 domains
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label
Determinants of syncytium form ...... e 1: role of the V1/V2 domains
@ast
Determinants of syncytium form ...... e 1: role of the V1/V2 domains
@en
prefLabel
Determinants of syncytium form ...... e 1: role of the V1/V2 domains
@ast
Determinants of syncytium form ...... e 1: role of the V1/V2 domains
@en
P2093
P2860
P1433
P1476
Determinants of syncytium form ...... e 1: role of the V1/V2 domains
@en
P2093
F González-Scarano
P2860
P304
P356
10.1128/JVI.74.2.693-701.2000
P577
2000-01-01T00:00:00Z