Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.
about
Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancerDNA damage response and apoptosis.Amphiregulin promotes BAX inhibition and resistance to gefitinib in non-small-cell lung cancers.Amphiregulin promotes resistance to gefitinib in nonsmall cell lung cancer cells by regulating Ku70 acetylation.SMAR1 coordinates HDAC6-induced deacetylation of Ku70 and dictates cell fate upon irradiation.Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair.Alterations in the cell cycle in the cerebellum of hyperbilirubinemic Gunn rat: a possible link with apoptosis?Histone deacetylase inhibitors sensitize lung cancer cells to hyperthermia: involvement of Ku70/SirT-1 in thermo-protectionBax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases.R-Roscovitine (Seliciclib) prevents DNA damage-induced cyclin A1 upregulation and hinders non-homologous end-joining (NHEJ) DNA repairAutophagy-dependent senescence in response to DNA damage and chronic apoptotic stress.Regulation of the proapoptotic factor Bax by Ku70-dependent deubiquitylation.A jekyll and hyde role of cyclin E in the genotoxic stress response: switching from cell cycle control to apoptosis regulation.The dark side of a tumor suppressor: anti-apoptotic p53.The probiotic Lactobacillus GG may augment intestinal host defense by regulating apoptosis and promoting cytoprotective responses in the developing murine gutCytosolic Ku70 regulates Bax-mediated cell death.Ku70 regulates Bax-mediated pathogenesis in laminin-alpha2-deficient human muscle cells and mouse models of congenital muscular dystrophy.Deletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repairDefective chromatin recruitment and retention of NHEJ core components in human tumor cells expressing a Cyclin E fragment.Caspases and kinases in a death grip.Developmental biology of gut-probiotic interaction.Apoptosis and molecular targeting therapy in cancer.MicroRNA-124 (miR-124) regulates Ku70 expression and is correlated with neuronal death induced by ischemia/reperfusion.PARP inhibition sensitizes to low dose-rate radiation TMPRSS2-ERG fusion gene-expressing and PTEN-deficient prostate cancer cells.Mcl-1 Phosphorylation defines ABT-737 resistance that can be overcome by increased NOXA expression in leukemic B cells.Potentiation of apoptosis by histone deacetylase inhibitors and doxorubicin combination: cytoplasmic cathepsin B as a mediator of apoptosis in multiple myeloma.A C-terminal fragment of Cyclin E, generated by caspase-mediated cleavage, is degraded in the absence of a recognizable phosphodegron.Ku80-deleted cells are defective at base excision repair.Src Acts as an Effector for Ku70-dependent Suppression of Apoptosis through Phosphorylation of Ku70 at Tyr-530.
P2860
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P2860
Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.
@ast
Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.
@en
type
label
Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.
@ast
Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.
@en
prefLabel
Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.
@ast
Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.
@en
P2860
P356
P1476
Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis
@en
P2093
Dragos Plesca
Suparna Mazumder
P2860
P304
P356
10.1128/MCB.01448-06
P407
P577
2007-02-26T00:00:00Z