Mechanism of interferon action: functionally distinct RNA-binding and catalytic domains in the interferon-inducible, double-stranded RNA-specific adenosine deaminase
about
Substrate recognition by ADAR1 and ADAR2Antiviral actions of interferonsThe human but not the Xenopus RNA-editing enzyme ADAR1 has an atypical nuclear localization signal and displays the characteristics of a shuttling proteinProtein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon responseAdenosine deaminases acting on RNA (ADARs) are both antiviral and proviralAn RNA editor, adenosine deaminase acting on double-stranded RNA (ADAR1).Effects of conserved RNA secondary structures on hepatitis delta virus genotype I RNA editing, replication, and virus productionAntisense RNA: function and fate of duplex RNA in cells of higher eukaryotes.RNA binding-independent dimerization of adenosine deaminases acting on RNA and dominant negative effects of nonfunctional subunits on dimer functions.Tipping the balance: antagonism of PKR kinase and ADAR1 deaminase functions by virus gene products.Adenosine deaminase acting on RNA 1 limits RIG-I RNA detection and suppresses IFN production responding to viral and endogenous RNAs.Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding.Adenosine deaminases acting on RNA, RNA editing, and interferon action.Host response to polyomavirus infection is modulated by RNA adenosine deaminase ADAR1 but not by ADAR2Chimeric double-stranded RNA-specific adenosine deaminase ADAR1 proteins reveal functional selectivity of double-stranded RNA-binding domains from ADAR1 and protein kinase PKR.Adenosine deaminase acting on RNA 1 (ADAR1) suppresses the induction of interferon by measles virus.Effects of length and location on the cellular response to double-stranded RNA.Distinct in vivo roles for double-stranded RNA-binding domains of the Xenopus RNA-editing enzyme ADAR1 in chromosomal targeting.Stress granule formation induced by measles virus is protein kinase PKR dependent and impaired by RNA adenosine deaminase ADAR1Editing of Cellular Self-RNAs by Adenosine Deaminase ADAR1 Suppresses Innate Immune Stress ResponsesOrganization of the mouse RNA-specific adenosine deaminase Adar1 gene 5'-region and demonstration of STAT1-independent, STAT2-dependent transcriptional activation by interferon.Adenosine deaminase ADAR1 increases gene expression at the translational level by decreasing protein kinase PKR-dependent eIF-2alpha phosphorylation.ADARs: viruses and innate immunity.RNA adenosine deaminase ADAR1 deficiency leads to increased activation of protein kinase PKR and reduced vesicular stomatitis virus growth following interferon treatment.Control of ADAR1 editing of hepatitis delta virus RNAsRNA editing and its control in hepatitis delta virus replication.ADAR RNA editing below the backbone.Nucleocytoplasmic distribution of human RNA-editing enzyme ADAR1 is modulated by double-stranded RNA-binding domains, a leucine-rich export signal, and a putative dimerization domain.Effects of social isolation and re-socialization on cognition and ADAR1 (p110) expression in mice.Adenosine Deaminase That Acts on RNA 3 (ADAR3) Binding to Glutamate Receptor Subunit B Pre-mRNA Inhibits RNA Editing in Glioblastoma.Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown.
P2860
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P2860
Mechanism of interferon action: functionally distinct RNA-binding and catalytic domains in the interferon-inducible, double-stranded RNA-specific adenosine deaminase
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Mechanism of interferon action ...... A-specific adenosine deaminase
@ast
Mechanism of interferon action ...... A-specific adenosine deaminase
@en
type
label
Mechanism of interferon action ...... A-specific adenosine deaminase
@ast
Mechanism of interferon action ...... A-specific adenosine deaminase
@en
prefLabel
Mechanism of interferon action ...... A-specific adenosine deaminase
@ast
Mechanism of interferon action ...... A-specific adenosine deaminase
@en
P2860
P1433
P1476
Mechanism of interferon action ...... A-specific adenosine deaminase
@en
P2093
P2860
P304
P407
P577
1996-03-01T00:00:00Z