Hemoglobin-driven pathophysiology is an in vivo consequence of the red blood cell storage lesion that can be attenuated in guinea pigs by haptoglobin therapy.
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Perioperative Red Blood Cell Transfusion: What We Do Not KnowInfection-related hemolysis and susceptibility to Gram-negative bacterial co-infectionThe Macrophage Mediates the Renoprotective Effects of Endotoxin PreconditioningHaptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug developmentRed Blood Cell Function and Dysfunction: Redox Regulation, Nitric Oxide Metabolism, Anemia.Transfusion of Old RBCs Induces Neuroinflammation and Cognitive Impairment.Assessing the influence of component processing and donor characteristics on quality of red cell concentrates using quality control data.A mechanistic investigation of thrombotic microangiopathy associated with IV abuse of Opana ER.Iron accelerates hemoglobin oxidation increasing mortality in vascular diseased guinea pigs following transfusion of stored blood.Randomized trial of red cell washing for the prevention of transfusion-associated organ injury in cardiac surgeryThe influence of storage age on iron status, oxidative stress and antioxidant protection in paediatric packed cell unitsMolecular controls of the oxygenation and redox reactions of hemoglobinRed blood cells ageing markers: a multi-parametric analysisAssociation between haptoglobin, hemopexin and mortality in adults with sepsisAcetaminophen attenuates lipid peroxidation in children undergoing cardiopulmonary bypassDoes prolonged storage of red blood cells cause harm?Modeling hemoglobin and hemoglobin:haptoglobin complex clearance in a non-rodent species-pharmacokinetic and therapeutic implications.Transfusion of older stored blood worsens outcomes in canines depending on the presence and severity of pneumonia.Angiotensin-converting enzyme inhibitor captopril reverses the adverse cardiovascular effects of polymerized hemoglobin.Elevation of plasma cell-free hemoglobin in pulmonary arterial hypertensionEffects of biliverdin administration on acute lung injury induced by hemorrhagic shock and resuscitation in ratsPeroxiredoxin-2 recycling is inhibited during erythrocyte storage.Serotonin is a key factor for mouse red blood cell survivalVasculopathy and pulmonary hypertension in sickle cell disease.Dissection of the radical reactions linked to fetal hemoglobin reveals enhanced pseudoperoxidase activity.Randomized, placebo-controlled trial of acetaminophen for the reduction of oxidative injury in severe sepsis: the Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis trial.Haptoglobin attenuates hemoglobin-induced heme oxygenase-1 in renal proximal tubule cells and kidneys of a mouse model of sickle cell disease.Established and theoretical factors to consider in assessing the red cell storage lesionReversal of hemochromatosis by apotransferrin in non-transfused and transfused Hbbth3/+ (heterozygous B1/B2 globin gene deletion) mice.Severe falciparum malaria treated with artesunate complicated by delayed onset haemolysis and acute kidney injury.The Human Endogenous Protection System against Cell-Free Hemoglobin and Heme Is Overwhelmed in Preeclampsia and Provides Potential Biomarkers and Clinical Indicators.Hemolysis and cell-free hemoglobin drive an intrinsic mechanism for human disease.Red blood cell washing, nitrite therapy, and antiheme therapies prevent stored red blood cell toxicity after trauma-hemorrhage.In a canine pneumonia model of exchange transfusion, altering the age but not the volume of older red blood cells markedly alters outcome.Transfused older stored red blood cells improve the clinical course and outcome in a canine lethal hemorrhage and reperfusion modelUnderstanding the erythrocyte storage lesion.Predicting storage-dependent damage to red blood cells using nitrite oxidation kinetics, peroxiredoxin-2 oxidation, and hemoglobin and free heme measurements.Effects of Aged Stored Autologous Red Blood Cells on Human Endothelial FunctionA novel hemoglobin-binding peptide reduces cell-free hemoglobin in murine hemolytic anemia.α-Hemoglobin stabilizing protein (AHSP) markedly decreases the redox potential and reactivity of α-subunits of human HbA with hydrogen peroxide
P2860
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P2860
Hemoglobin-driven pathophysiology is an in vivo consequence of the red blood cell storage lesion that can be attenuated in guinea pigs by haptoglobin therapy.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Hemoglobin-driven pathophysiol ...... a pigs by haptoglobin therapy.
@ast
Hemoglobin-driven pathophysiol ...... a pigs by haptoglobin therapy.
@en
type
label
Hemoglobin-driven pathophysiol ...... a pigs by haptoglobin therapy.
@ast
Hemoglobin-driven pathophysiol ...... a pigs by haptoglobin therapy.
@en
prefLabel
Hemoglobin-driven pathophysiol ...... a pigs by haptoglobin therapy.
@ast
Hemoglobin-driven pathophysiol ...... a pigs by haptoglobin therapy.
@en
P2093
P2860
P356
P1476
Hemoglobin-driven pathophysiol ...... ea pigs by haptoglobin therapy
@en
P2093
Claudia P Pereira
Felice D'Agnillo
Florence Vallelian
Jin Hyen Baek
Matthew C Williams
Paul W Buehler
Yiping Jia
P2860
P304
P356
10.1172/JCI59770
P407
P50
P577
2012-03-26T00:00:00Z