Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice.
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High stearoyl-CoA desaturase 1 expression is associated with shorter survival in breast cancer patientsAberrant Lipid Metabolism Promotes Prostate Cancer: Role in Cell Survival under Hypoxia and Extracellular Vesicles BiogenesisA novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosisLipid metabolism in prostate cancerBroad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and LipogenesisCritical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway.Inhibition of stearoyl-CoA desaturase 1 expression induces CHOP-dependent cell death in human cancer cells.Oxidized LDL receptor 1 (OLR1) as a possible link between obesity, dyslipidemia and cancer.StearoylCoA desaturase-5: a novel regulator of neuronal cell proliferation and differentiation.SCD1 Expression is dispensable for hepatocarcinogenesis induced by AKT and Ras oncogenes in mice.Decreased level of phosphatidylcholine (16:0/20:4) in multiple myeloma cells compared to plasma cells: a single-cell MALDI-IMS approach.17β-estradiol induces stearoyl-CoA desaturase-1 expression in estrogen receptor-positive breast cancer cellsSubcutaneous adipose tissue fatty acid desaturation in adults with and without rare adipose disorders.Hepatic SirT1-Dependent Gain of Function of Stearoyl-CoA Desaturase-1 Conveys Dysmetabolic and Tumor Progression Functions.Repression of endometrial tumor growth by targeting SREBP1 and lipogenesisPPARγ isoforms differentially regulate metabolic networks to mediate mouse prostatic epithelial differentiation.p53 attenuates AKT signaling by modulating membrane phospholipid compositionDesign, radiosynthesis, and evaluation of radiotracers for positron emission tomography imaging of stearoyl-CoA desaturase-1.A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy.Chronic exposure to chewing tobacco selects for overexpression of stearoyl-CoA desaturase in normal oral keratinocytes.Androgens promote prostate cancer cell growth through induction of autophagy.Metabolic Effect of Estrogen Receptor Agonists on Breast Cancer Cells in the Presence or Absence of Carbonic Anhydrase Inhibitors.Cellular fatty acid metabolism and cancerStearoyl-CoA desaturase enzyme 1 inhibition reduces glucose utilization for de novo fatty acid synthesis and cell proliferation in 3T3-L1 adipocytes.Metabolic intervention on lipid synthesis converging pathways abrogates prostate cancer growth.Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development.Targeting Lipid Metabolic Reprogramming as Anticancer Therapeutics.Stearoyl CoA desaturase (SCD) facilitates proliferation of prostate cancer cells through enhancement of androgen receptor transactivation.Role of abnormal lipid metabolism in development, progression, diagnosis and therapy of pancreatic cancer.Prediction of therapeutic microRNA based on the human metabolic network.Fenretinide induces ubiquitin-dependent proteasomal degradation of stearoyl-CoA desaturase in human retinal pigment epithelial cells.Emerging roles of lipid metabolism in cancer metastasis.Stearoyl CoA desaturase 1: role in cellular inflammation and stressThe role of stearoyl-CoA desaturase in obesity, insulin resistance, and inflammation.Lipids and prostate cancer.The fat side of prostate cancer.Roles of StearoylCoA Desaturase-1 in the Regulation of Cancer Cell Growth, Survival and Tumorigenesis.17β-estradiol-induced ACSL4 protein expression promotes an invasive phenotype in estrogen receptor positive mammary carcinoma cells.Lipid desaturation - the next step in targeting lipogenesis in cancer?Oncogenic PI3K and K-Ras stimulate de novo lipid synthesis through mTORC1 and SREBP.
P2860
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P2860
Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Abrogation of de novo lipogene ...... te cancer progression in mice.
@ast
Abrogation of de novo lipogene ...... te cancer progression in mice.
@en
type
label
Abrogation of de novo lipogene ...... te cancer progression in mice.
@ast
Abrogation of de novo lipogene ...... te cancer progression in mice.
@en
prefLabel
Abrogation of de novo lipogene ...... te cancer progression in mice.
@ast
Abrogation of de novo lipogene ...... te cancer progression in mice.
@en
P2093
P2860
P1476
Abrogation of de novo lipogene ...... te cancer progression in mice.
@en
P2093
Alexandre de la Taille
Christophe Avancès
Claude Sardet
Corinne Henriquet
François Iborra
Françoise Michel
Geneviève Rodier
Hubert Blancou
Jean Paul Cristol
Lluis Fajas
P2860
P304
P356
10.1158/1535-7163.MCT-09-1064
P577
2010-06-08T00:00:00Z