Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein.
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Structure--function relationships in HIV-1 Nef.Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complexCo-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulationInteraction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivityExosomes are unlikely involved in intercellular Nef transferHIV-1 infection of T cells and macrophages are differentially modulated by virion-associated Hck: a Nef-dependent phenomenonRegions of human immunodeficiency virus type 1 nef required for function in vivoHuman immunodeficiency virus type 1 particles pseudotyped with envelope proteins that fuse at low pH no longer require Nef for optimal infectivityHuman immunodeficiency virus type 1 Nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity.Nef does not contribute to replication differences between R5 pre-AIDS and AIDS HIV-1 clones from patient ACH142The effect of viral regulatory protein expression on gene delivery by human immunodeficiency virus type 1 vectors produced in stable packaging cell lines.Generation and characterization of a stable cell population releasing fluorescent HIV-1-based Virus Like Particles in an inducible way.Phosphorylation and proteolytic cleavage of gag proteins in budded simian immunodeficiency virus.gag, vif, and nef genes contribute to the homologous viral interference induced by a nonproducer human immunodeficiency virus type 1 (HIV-1) variant: identification of novel HIV-1-inhibiting viral protein mutants.The proteolytic cleavage of human immunodeficiency virus type 1 Nef does not correlate with its ability to stimulate virion infectivity.Virion incorporation of human immunodeficiency virus type 1 Nef is mediated by a bipartite membrane-targeting signal: analysis of its role in enhancement of viral infectivity.Nef-induced major histocompatibility complex class I down-regulation is functionally dissociated from its virion incorporation, enhancement of viral infectivity, and CD4 down-regulationIsolation of human immunodeficiency virus type 1 cores: retention of Vpr in the absence of p6(gag).CCR5 signal transduction in macrophages by human immunodeficiency virus and simian immunodeficiency virus envelopesAssociation of Nef with the human immunodeficiency virus type 1 core.Nef enhances human immunodeficiency virus type 1 infectivity resulting from intervirion fusion: evidence supporting a role for Nef at the virion envelope.Nef from human immunodeficiency virus type 1(F12) inhibits viral production and infectivitySecreted phospholipases A(2), a new class of HIV inhibitors that block virus entry into host cells.Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions.Restoration of wild-type infectivity to human immunodeficiency virus type 1 strains lacking nef by intravirion reverse transcription.Modulation of HIV-1 infectivity by MAPK, a virion-associated kinase.MLV glycosylated-Gag is an infectivity factor that rescues Nef-deficient HIV-1.Positive and negative aspects of the human immunodeficiency virus protease: development of inhibitors versus its role in AIDS pathogenesisNef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41.Nef alleles from all major HIV-1 clades activate Src-family kinases and enhance HIV-1 replication in an inhibitor-sensitive manner.Nef stimulates human immunodeficiency virus type 1 replication in primary T cells by enhancing virion-associated gp120 levels: coreceptor-dependent requirement for Nef in viral replication.Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptorsNef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes.Proteomic profiling of SupT1 cells reveal modulation of host proteins by HIV-1 Nef variantsDynamin 2 is required for the enhancement of HIV-1 infectivity by Nef.The nef gene products of both simian and human immunodeficiency viruses enhance virus infectivity and are functionally interchangeable.Development of a novel anti-HIV-1 agent from within: effect of chimeric Vpr-containing protease cleavage site residues on virus replicationPol-specific CD8+ T cells recognize simian immunodeficiency virus-infected cells prior to Nef-mediated major histocompatibility complex class I downregulation.HIV-1 Nef increases T cell activation in a stimulus-dependent manner.Human macrophages support persistent transcription from unintegrated HIV-1 DNA.
P2860
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P2860
Producer-cell modification of human immunodeficiency virus type 1: Nef is a virion protein.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Producer-cell modification of ...... pe 1: Nef is a virion protein.
@ast
Producer-cell modification of ...... pe 1: Nef is a virion protein.
@en
type
label
Producer-cell modification of ...... pe 1: Nef is a virion protein.
@ast
Producer-cell modification of ...... pe 1: Nef is a virion protein.
@en
prefLabel
Producer-cell modification of ...... pe 1: Nef is a virion protein.
@ast
Producer-cell modification of ...... pe 1: Nef is a virion protein.
@en
P2093
P2860
P1433
P1476
Producer-cell modification of ...... pe 1: Nef is a virion protein.
@en
P2093
D D Richman
J C Guatelli
M W Pandori
P2860
P304
P407
P577
1996-07-01T00:00:00Z