The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis
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Molecular Studies of HTLV-1 Replication: An UpdateNF-kappaB activation: Tax sumoylation is out, but what about Tax ubiquitination?Functional genetic variant of WW domain-containing oxidoreductase (WWOX) gene is associated with hepatocellular carcinoma risk.The noncanonical NF-κB pathway.An RNA interference screen identifies the Deubiquitinase STAMBPL1 as a critical regulator of human T-cell leukemia virus type 1 tax nuclear export and NF-κB activation.Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesisOncovirus Kaposi sarcoma herpesvirus (KSHV) represses tumor suppressor PDLIM2 to persistently activate nuclear factor κB (NF-κB) and STAT3 transcription factors for tumorigenesis and tumor maintenance.Mutual regulation between deubiquitinase CYLD and retroviral oncoprotein TaxNF-κB and cancer: a paradigm of Yin-Yang.NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function.Role of WWOX and NF-κB in lung cancer progressionPDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease.Introduction to a thematic issue for WWOX.Role of WW domain proteins WWOX in development, prognosis, and treatment response of glioma.Regulation of cell signaling and apoptosis by tumor suppressor WWOX.Strategies of oncogenic microbes to deal with WW domain-containing oxidoreductaseAcetylation at lysine 346 controls the transforming activity of the HTLV-1 Tax oncoprotein in the Rat-1 fibroblast modelKaposi's sarcoma herpesvirus (KSHV) microRNA K12-1 functions as an oncogene by activating NF-κB/IL-6/STAT3 signaling.The common fragile site FRA16D gene product WWOX: roles in tumor suppression and genomic stability.Regulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway.Integrated molecular analysis of adult T cell leukemia/lymphoma.Recurrent alterations of the WW domain containing oxidoreductase gene spanning the common fragile site FRA16D in multiple myeloma and monoclonal gammopathy of undetermined significance.Lithium promotes neural precursor cell proliferation: evidence for the involvement of the non-canonical GSK-3β-NF-AT signaling.Human T cell leukemia virus type 2 tax-mediated NF-κB activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO.New approaches to the inhibition of replication of viral pathogens.Loss of lung WWOX expression causes neutrophilic inflammation.Phosphorylation/de-phosphorylation in specific sites of tumor suppressor WWOX and control of distinct biological events.S100A9+ MDSC and TAM-mediated EGFR-TKI resistance in lung adenocarcinoma: the role of RELB.Myeloid STAT3 Promotes Lung Tumorigenesis by Transforming Tumor Immunosurveillance into Tumor-Promoting Inflammation.Unlocking the NF-κB Conundrum: Embracing Complexity to Achieve Specificity.Modeling WWOX Loss of Function : What Have We Learned?
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P2860
The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
The tumor suppressor gene WWOX ...... V-I Tax-mediated tumorigenesis
@ast
The tumor suppressor gene WWOX ...... V-I Tax-mediated tumorigenesis
@en
type
label
The tumor suppressor gene WWOX ...... V-I Tax-mediated tumorigenesis
@ast
The tumor suppressor gene WWOX ...... V-I Tax-mediated tumorigenesis
@en
prefLabel
The tumor suppressor gene WWOX ...... V-I Tax-mediated tumorigenesis
@ast
The tumor suppressor gene WWOX ...... V-I Tax-mediated tumorigenesis
@en
P2093
P2860
P1433
P1476
The tumor suppressor gene WWOX ...... V-I Tax-mediated tumorigenesis
@en
P2093
Arnold B Rabson
Chie Ishikawa
Gutian Xiao
Rami I Aqeilan
Zhaoxia Qu
P2860
P304
P356
10.1182/BLOOD-2010-08-303073
P407
P577
2010-11-29T00:00:00Z