Human bronchial cyclic nucleotide phosphodiesterase isoenzymes: biochemical and pharmacological analysis using selective inhibitors.
about
Cyclic AMP-dependent transcriptional up-regulation of phosphodiesterase 4D5 in human airway smooth muscle cells. Identification and characterization of a novel PDE4D5 promoterPhosphodiesterase 3 inhibition and cough in elderly asthmatics.Targeting the sarcomere to correct muscle functionImaging cytoplasmic cAMP in mouse brainstem neuronsBiochanin a, a phytoestrogenic isoflavone with selective inhibition of phosphodiesterase 4, suppresses ovalbumin-induced airway hyperresponsiveness.ABCD of the phosphodiesterase family: interaction and differential activity in COPDS-Petasin, the Main Sesquiterpene of Petasites formosanus, Inhibits Phosphodiesterase Activity and Suppresses Ovalbumin-Induced Airway Hyperresponsiveness.Modulation of cell adhesion molecule expression and function on human lung microvascular endothelial cells by inhibition of phosphodiesterases 3 and 4.KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K+ channelsHesperetin-7,3'-O-dimethylether selectively inhibits phosphodiesterase 4 and effectively suppresses ovalbumin-induced airway hyperresponsiveness with a high therapeutic ratio.Hesperetin, a Selective Phosphodiesterase 4 Inhibitor, Effectively Suppresses Ovalbumin-Induced Airway Hyperresponsiveness without Influencing Xylazine/Ketamine-Induced AnesthesiaEffects of phosphodiesterase isoenzyme inhibitors on cutaneous inflammation in the guinea-pigHesperidin-3'-o-methylether is more potent than hesperidin in phosphodiesterase inhibition and suppression of ovalbumin-induced airway hyperresponsiveness.Phosphodiesterase inhibitors.Identification and function of cyclic nucleotide phosphodiesterase isoenzymes in airway epithelial cells.Potentiation of the bronchoprotective effects of vasoactive intestinal peptide, isoprenaline, and theophylline against histamine challenge in anaesthetised guinea pigs by adrenomedullin.Phosphodiesterase isozymes: molecular targets for novel antiasthma agents.Pulmonary effects of type V cyclic GMP specific phosphodiesterase inhibition in the anaesthetized guinea-pig.Anti-inflammatory and bronchodilator properties of RP 73401, a novel and selective phosphodiesterase type IV inhibitor.Effects of rolipram and siguazodan on the human isolated bronchus and their interaction with isoprenaline and sodium nitroprussideThe effect of selective and non-selective phosphodiesterase inhibitors on allergen- and leukotriene C(4)-induced contractions in passively sensitized human airways.Effects of RP 73401, a novel, potent and selective phosphodiesterase type 4 inhibitor, on contractility of human, isolated bronchial muscleEffects of SCA40 on human isolated bronchus and human polymorphonuclear leukocytes: comparison with rolipram, SKF94120 and levcromakalim.Novel relaxant effects of RPL554 on guinea pig tracheal smooth muscle contractility.Relaxation of guinea-pig trachea by cyclic AMP phosphodiesterase inhibitors and their enhancement by sodium nitroprusside.Modulation of spasmogen-stimulated Ins(1,4,5)P3 generation and functional responses by selective inhibitors of types 3 and 4 phosphodiesterase in airways smooth muscle.The toxicity of SCH 351591, a novel phosphodiesterase-4 inhibitor, in Cynomolgus monkeys.Phosphodiesterase IV inhibitors synergistically potentiate relaxation induced by forskolin in guinea-pig trachea.Correlations of PDE-4 inhibition between enzymes of smooth muscle and inflammatory cell sources.The short-term bronchodilator effects of the dual phosphodiesterase 3 and 4 inhibitor RPL554 in COPD
P2860
Q24301633-08E58FB0-11B1-4770-B878-203E8D7A5D6CQ25255659-0E3D51C5-960C-4001-B723-CD6EBE2F120CQ28260629-CCEDF260-0116-427E-8481-45B071B2D547Q33423211-C414DA96-9BD3-4D8D-8867-9B68B4BAC278Q34706585-5E1D04A7-4DD4-47AD-948A-928FCD9F5B7AQ34961511-2D5FE7CD-AFC3-4263-BA76-C21BC2DF7BFDQ34981983-81F92870-EB5D-44C0-9590-2A299883AB26Q35027556-399417D5-0784-4952-85EF-ED292C1BD607Q35047472-F36F365D-E1C7-4114-B211-79F0EB6AA574Q35576638-65487516-50BF-4E24-A1D6-D5CD03F33CF6Q35792013-0E74AA69-3291-40BF-B1B2-7E4C656CBD7DQ35874736-2C183FE2-121C-4BAB-A301-19706942F2ACQ36311412-FB6BBCED-AE9F-40BB-BABB-3CE99A475BE3Q36364429-EFD9CF74-A2AE-434B-8398-DD9457D900BDQ40977361-1C1AAF99-95BD-4AB7-B51C-F78CF4518DF5Q41208639-60C8B241-F438-44F1-BC34-AD3CF6E37C3FQ41708863-EEBF7D80-E864-439C-8C04-41206C5402C3Q41872509-18F16915-091A-4D9D-9845-57FF00DED451Q41911293-256FC4A5-8815-4F0B-B563-932AD7BF8862Q41954067-D1D75D74-9505-4243-84B5-3412ED84C007Q41979311-F4645017-E3E2-43D3-8F0D-B0882238B422Q42002291-35396754-7CF0-482C-AAE0-C0BC35D5C227Q42269344-148837C2-334C-45B8-B601-67486BE2EABBQ42419157-1D7A0580-E0CB-430B-A079-AE2709F298B0Q42701926-2BFCE894-5018-454C-84B4-6AFE2A986318Q43182639-80F66D41-7F64-4414-8842-EBD09F2D0228Q44760134-67F4CC0E-F4DA-4F14-96EB-8D5F19B61606Q46521491-F47E1D68-65C0-407A-8012-C0C45165D03EQ46709322-4C35047F-8812-475B-A8EB-0C7D87B6DB41Q58701370-B4A0C37B-DE9A-4B73-A888-F2789D08680D
P2860
Human bronchial cyclic nucleotide phosphodiesterase isoenzymes: biochemical and pharmacological analysis using selective inhibitors.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Human bronchial cyclic nucleot ...... is using selective inhibitors.
@ast
Human bronchial cyclic nucleot ...... is using selective inhibitors.
@en
type
label
Human bronchial cyclic nucleot ...... is using selective inhibitors.
@ast
Human bronchial cyclic nucleot ...... is using selective inhibitors.
@en
prefLabel
Human bronchial cyclic nucleot ...... is using selective inhibitors.
@ast
Human bronchial cyclic nucleot ...... is using selective inhibitors.
@en
P2093
P2860
P1476
Human bronchial cyclic nucleot ...... is using selective inhibitors.
@en
P2093
Nicholson CD
Philpott AJ
van Amsterdam RG
P2860
P304
P356
10.1111/J.1476-5381.1992.TB14451.X
P407
P577
1992-08-01T00:00:00Z