Inhibition of eosinophil cyclic nucleotide PDE activity and opsonised zymosan-stimulated respiratory burst by 'type IV'-selective PDE inhibitors.
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Functional and biochemical evidence for diazepam as a cyclic nucleotide phosphodiesterase type 4 inhibitorEffects of PDE4 inhibitors on lipopolysaccharide-induced priming of superoxide anion production from human mononuclear cellsThe effect of selective phosphodiesterase 3 and 4 isoenzyme inhibitors and established anti-asthma drugs on inflammatory cell activationSimultaneous determination of YM-64227, a phosphodiesterase type 4 inhibitor, and its five metabolites in dog plasma by high-performance liquid chromatography with fluorescence detection.Phosphodiesterase type 4 inhibitors: potential in the treatment of multiple sclerosis?Effects of phosphodiesterase inhibitors on human lung mast cell and basophil function.Characterization of phosphodiesterase 4 in guinea-pig macrophages: multiple activities, association states and sensitivity to selective inhibitorsA comparison of the inhibitory activity of PDE4 inhibitors on leukocyte PDE4 activity in vitro and eosinophil trafficking in vivoProspects for selective cyclic nucleotide phosphodiesterase inhibitors in the treatment of bronchial asthma.Recent advances in asthma.Human bronchial cyclic nucleotide phosphodiesterase isoenzymes: biochemical and pharmacological analysis using selective inhibitors.Cyclic AMP-elevating agents prolong or inhibit eosinophil survival depending on prior exposure to GM-CSFEffects of agents which elevate cyclic AMP on guinea-pig eosinophil homotypic aggregationEffects of phosphodiesterase isoenzyme inhibitors on cutaneous inflammation in the guinea-pigExistence of rolipram-sensitive phosphodiesterase in rat megakaryocyte.Phosphodiesterase inhibitors.Human phosphodiesterase 4A: characterization of full-length and truncated enzymes expressed in COS cells.Suppression of eosinophil function by RP 73401, a potent and selective inhibitor of cyclic AMP-specific phosphodiesterase: comparison with rolipram.Aspirin attenuates the anti-inflammatory effects of theophylline via inhibition of cAMP production in mice with non-eosinophilic asthmaTwo new roles for theophylline in the asthmatic?Anti-inflammatory effects of theophylline and selective phosphodiesterase inhibitors.Phosphodiesterase isozymes: molecular targets for novel antiasthma agents.Phosphodiesterase 4 in macrophages: relationship between cAMP accumulation, suppression of cAMP hydrolysis and inhibition of [3H]R-(-)-rolipram binding by selective inhibitorsEffects of theophylline and rolipram on leukotriene C4 (LTC4) synthesis and chemotaxis of human eosinophils from normal and atopic subjects.Phosphodiesterase IV inhibitors as therapy for eosinophil-induced lung injury in asthma.Regulation of tumour necrosis factor production by adrenal hormones in vivo: insights into the antiinflammatory activity of rolipram.Acute versus chronic administration of phosphodiesterase inhibitors on allergen-induced pulmonary cell influx in sensitized guinea-pigs.The effect of cyclic AMP and cyclic GMP phosphodiesterase inhibitors on the superoxide burst of guinea-pig peritoneal macrophages.Suppression of human inflammatory cell function by subtype-selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B.Differential effects of non-selective and selective phosphodiesterase inhibitors on human eosinophil functions.Prevention by phosphodiesterase inhibitors of antigen-induced contraction of guinea-pig colonic smooth muscle.Effects of inhibitors of phosphodiesterase, on antigen-induced bronchial hyperreactivity in conscious sensitized guinea-pigs and airway leukocyte infiltration.Rolipram inhibits airway microvascular leakage induced by platelet-activating factor, histamine and bradykinin in guinea-pigs.Correlations of PDE-4 inhibition between enzymes of smooth muscle and inflammatory cell sources.Activation of guinea pig eosinophil respiratory burst by leukotriene B4: role of protein kinase C.PDE4 inhibition and a corticosteroid in chronically antigen exposed conscious guinea-pigs.Effects of solubilization and vanadate/glutathione complex on inhibitor potencies against eosinophil cyclic AMP-specific phosphodiesterase.Signal transduction and activation of the NADPH oxidase in eosinophils.
P2860
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P2860
Inhibition of eosinophil cyclic nucleotide PDE activity and opsonised zymosan-stimulated respiratory burst by 'type IV'-selective PDE inhibitors.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Inhibition of eosinophil cycli ...... IV'-selective PDE inhibitors.
@ast
Inhibition of eosinophil cycli ...... IV'-selective PDE inhibitors.
@en
type
label
Inhibition of eosinophil cycli ...... IV'-selective PDE inhibitors.
@ast
Inhibition of eosinophil cycli ...... IV'-selective PDE inhibitors.
@en
prefLabel
Inhibition of eosinophil cycli ...... IV'-selective PDE inhibitors.
@ast
Inhibition of eosinophil cycli ...... IV'-selective PDE inhibitors.
@en
P2093
P2860
P1476
Inhibition of eosinophil cycli ...... IV'-selective PDE inhibitors.
@en
P2093
P2860
P304
P356
10.1111/J.1476-5381.1991.TB09790.X
P407
P577
1991-06-01T00:00:00Z