CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection.
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Ribavirin increases mitogen- and antigen-induced expression of CD40L on CD4+ T cells in vivoCD40-CD40 Ligand Interactions Promote Trafficking of CD8+ T Cells into the Brain and Protection against West Nile Virus EncephalitisCD70 expression by dendritic cells plays a critical role in the immunogenicity of CD40-independent, CD4+ T cell-dependent, licensed CD8+ T cell responsesType I interferon suppresses virus-specific B cell responses by modulating CD8(+) T cell differentiationThe role of cytokines which signal through the common gamma chain cytokine receptor in the reversal of HIV specific CD4(+) and CD8(+) T cell anergyPlatelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus.Requirement of CD40-CD40 ligand interaction for elimination of Cryptosporidium parvum from mice.T-Cell-independent immunoglobulin G responses in vivo are elicited by live-virus infection but not by immunization with viral proteins or virus-like particles.Long-term CD4 Th1 and Th2 memory following acute lymphocytic choriomeningitis virus infectionRequirement for CD40 ligand, CD4(+) T cells, and B cells in an infectious mononucleosis-like syndromeEstablishment and maintenance of long-term murine gammaherpesvirus 68 latency in B cells in the absence of CD40.Epidermal powder immunization induces both cytotoxic T-lymphocyte and antibody responses to protein antigens of influenza and hepatitis B viruses.Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection.Host factors influencing viral persistence.IFN-λ exerts opposing effects on T cell responses depending on the chronicity of the virus infection.Dual roles of CD40 on microbial containment and the development of immunopathology in response to persistent fungal infection in the lungPrevention of airway allograft tolerance by polyinosinic:polycytidylic acid requires type I interferon responsiveness for mouse airway obliterationMechanism of reduced T-cell effector functions and class-switched antibody responses to herpes simplex virus type 2 in the absence of B7 costimulationNK cells and their ability to modulate T cells during virus infectionsCD40 ligand deficiency: neurologic sequelae with radiographic correlationAntiviral CD4 and CD8 T-cell memory: differences in the size of the response and activation requirements.Localization of CD4+ T cell epitope hotspots to exposed strands of HIV envelope glycoprotein suggests structural influences on antigen processingBcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation.CD4 memory T cells survive and proliferate but fail to differentiate in the absence of CD40CD8(+) T cells mediate CD40-independent maturation of dendritic cells in vivoTRANCE, a tumor necrosis factor family member critical for CD40 ligand-independent T helper cell activationNeonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells.CD40 ligand is not essential for induction of type 1 cytokine responses or protective immunity after primary or secondary infection with histoplasma capsulatum.Vaccination of BALB/c mice with Escherichia coli-expressed vaccinia virus proteins A27L, B5R, and D8L protects mice from lethal vaccinia virus challengeT Follicular Helper Cell-Dependent Clearance of a Persistent Virus Infection Requires T Cell Expression of the Histone Demethylase UTX.Cytokine-mediated programmed proliferation of virus-specific CD8(+) memory T cells.Quantitative PCR technique for detecting lymphocytic choriomeningitis virus in vivo.NK cells inhibit humoral immunity by reducing the abundance of CD4+ T follicular helper cells during a chronic virus infectionCD4+ T helper cells use CD154-CD40 interactions to counteract T reg cell-mediated suppression of CD8+ T cell responses to influenza.Requirement of B cells for generating CD4+ T cell memory.Strategic nonmyeloablative conditioning: CD154:CD40 costimulatory blockade at primary bone marrow transplantation promotes engraftment for secondary bone marrow transplantation after engraftment failure.Tumor necrosis factor receptor/tumor necrosis factor family members in antiviral CD8 T-cell immunity.Role of tumor necrosis factor receptors in regulating CD8 T-cell responses during acute lymphocytic choriomeningitis virus infectionB7 costimulation is critical for antibody class switching and CD8(+) cytotoxic T-lymphocyte generation in the host response to vesicular stomatitis virus.High frequency of virus-specific interleukin-2-producing CD4(+) T cells and Th1 dominance during lymphocytic choriomeningitis virus infection.
P2860
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P2860
CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
CD40 ligand-deficient mice gen ...... response to a viral infection.
@ast
CD40 ligand-deficient mice gen ...... response to a viral infection.
@en
type
label
CD40 ligand-deficient mice gen ...... response to a viral infection.
@ast
CD40 ligand-deficient mice gen ...... response to a viral infection.
@en
prefLabel
CD40 ligand-deficient mice gen ...... response to a viral infection.
@ast
CD40 ligand-deficient mice gen ...... response to a viral infection.
@en
P2093
P2860
P1433
P1476
CD40 ligand-deficient mice gen ...... response to a viral infection.
@en
P2093
I S Grewal
J K Whitmire
M K Slifka
R A Flavell
P2860
P304
P407
P577
1996-12-01T00:00:00Z