Spinal cord NMDA receptor-mediated activation of mammalian target of rapamycin is required for the development and maintenance of bone cancer-induced pain hypersensitivities in rats.
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AMPK: An emerging target for modification of injury-induced pain plasticity.mTOR, a new potential target for chronic pain and opioid-induced tolerance and hyperalgesiaTranslational control of nociception via 4E-binding protein 1Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance and hyperalgesiaAdenosine Monophosphate-activated Protein Kinase (AMPK) Activators For the Prevention, Treatment and Potential Reversal of Pathological Pain.mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK.mTOR kinase: a possible pharmacological target in the management of chronic pain.Activation of the Mammalian Target of Rapamycin in the Rostral Ventromedial Medulla Contributes to the Maintenance of Nerve Injury-Induced Neuropathic Pain in RatmTOR and its downstream pathway are activated in the dorsal root ganglion and spinal cord after peripheral inflammation, but not after nerve injuryProtein kinase B/Akt is required for complete Freund's adjuvant-induced upregulation of Nav1.7 and Nav1.8 in primary sensory neurons.Peripheral administration of translation inhibitors reverses increased hyperalgesia in a model of chronic pain in the rat.Inhibition of Mammalian Target of Rapamycin (mTOR) Signaling in the Insular Cortex Alleviates Neuropathic Pain after Peripheral Nerve Injury.Drug repositioning: playing dirty to kill pain.mTOR in Brain Physiology and Pathologies.Localized experimental bone metastasis drives osteolysis and sensory hypersensitivity at distant non-tumor-bearing sites.Targeting AMPK for the Alleviation of Pathological Pain.Osteolysis and pain due to experimental bone metastases are improved by treatment with rapamycin.Protease-activated receptor 2 in dorsal root ganglion contributes to peripheral sensitization of bone cancer pain.Blocking mammalian target of rapamycin alleviates bone cancer pain and morphine tolerance via µ-opioid receptor.Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK.mTOR and Erk1/2 Signaling in the Cerebrospinal Fluid-Contacting Nucleus is Involved in Neuropathic Pain.[EXPRESS] DNMT3a contributes to the development and maintenance of bone cancer pain by silencing Kv1.2 expression in spinal cord dorsal horn.Translational Control Mechanisms in Persistent Pain.Rapamycin ameliorates neuropathic pain by activating autophagy and inhibiting interleukin-1β in the rat spinal cord.Rapamycin: A promising agent to treat cancer pain?CX3CR1-Mediated Akt1 Activation Contributes to the Paclitaxel-Induced Painful Peripheral Neuropathy in Rats.eIF4E-Dependent Translational Control: A Central Mechanism for Regulation of Pain Plasticity
P2860
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P2860
Spinal cord NMDA receptor-mediated activation of mammalian target of rapamycin is required for the development and maintenance of bone cancer-induced pain hypersensitivities in rats.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Spinal cord NMDA receptor-medi ...... in hypersensitivities in rats.
@ast
Spinal cord NMDA receptor-medi ...... in hypersensitivities in rats.
@en
type
label
Spinal cord NMDA receptor-medi ...... in hypersensitivities in rats.
@ast
Spinal cord NMDA receptor-medi ...... in hypersensitivities in rats.
@en
prefLabel
Spinal cord NMDA receptor-medi ...... in hypersensitivities in rats.
@ast
Spinal cord NMDA receptor-medi ...... in hypersensitivities in rats.
@en
P2093
P2860
P1433
P1476
Spinal cord NMDA receptor-medi ...... in hypersensitivities in rats.
@en
P2093
Ming-Hung Shih
Myron Yaster
Sheng-Chin Kao
Yuan-Xiang Tao
P2860
P304
P356
10.1016/J.JPAIN.2011.12.006
P577
2012-02-15T00:00:00Z