Agonistic and antagonistic properties of the bradykinin B2 receptor antagonist, Hoe 140, in isolated blood vessels from different species
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Icatibant: HOE 140, JE 049, JE049In various tumour cell lines the peptide bradykinin B(2) receptor antagonist, Hoe 140 (Icatibant), may act as mitogenic agonistBradykinin increases Na(+)-K(+) pump activity in cultured guinea-pig tracheal smooth muscle cellsExpression and function of bradykinin B1 and B2 receptors in normal and inflamed rat urinary bladder urotheliumBradykinin-induced contractions of canine saphenous veins: mediation by B2 receptors and involvement of eicosanoids.Alteration of flow-induced dilatation in mesenteric resistance arteries of L-NAME treated rats and its partial association with induction of cyclo-oxygenase-2.Effects of trout bradykinin on the motility of the trout stomach and intestine: evidence for a receptor distinct from mammalian B1 and B2 subtypesRole of bradykinin receptors in the renal effects of inhibition of angiotensin converting enzyme and endopeptidases 24.11 and 24.15 in conscious rabbits.Antagonist, partial agonist and antiproliferative actions of B-9870 (CU201) as a function of the expression and density of the bradykinin B1 and B2 receptorsEffects of kinin B(1) and B(2) receptor antagonists on overactive urinary bladder syndrome induced by spinal cord injury in rats.Bradykinin and changes in microvascular permeability in the hamster cheek pouch: role of nitric oxide.Development of a synthetic gene network to modulate gene expression by mechanical forces.Analgesic targets: today and tomorrow.Icatibant , the bradykinin B2 receptor antagonist with target to the interconnected kinin systems.The role of nitric oxide in the responses of the ovine digital artery to vasoactive agents and modification of these responses by endotoxin and cytokines.Pharmacological and functional characterization of the guinea-pig B2 bradykinin receptor stably expressed in CHO-K1 cell lineSpontaneous human B2 bradykinin receptor activity determines the action of partial agonists as agonists or inverse agonists. Effect of basal desensitization.LF 16-0687 Ms, a bradykinin B2 receptor antagonist, reduces ischemic brain injury in a murine model of transient focal cerebral ischemia.The mechanism of bradykinin-induced endothelium-dependent contraction and relaxation in the porcine interlobar renal artery.Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo.Vascular kinin B(1) and B(2) receptor-mediated effects in the rat isolated perfused kidney - differential regulationsCloning and functional characterization of the ornithokinin receptor. Recognition of the major kinin receptor antagonist, HOE140, as a full agonist.Amlodipine, but not verapamil or nifedipine, dilates rabbit femoral artery largely through a nitric oxide- and kinin-dependent mechanism.Kinin B2 receptor-mediated contraction of tail arteries from normal or streptozotocin-induced diabetic rats.Changes in amino-terminal portion of human B2 receptor selectively increase efficacy of synthetic ligand HOE 140 but not of cognate ligand bradykinin.In vitro and in vivo effects of the new nonpeptide bradykinin B2 receptor antagonist, LF 16-0335C, on guinea-pig and rat kinin receptors.Comparative studies on differential inhibition of the renin - angiotensin system in the anesthetized guinea pig.
P2860
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P2860
Agonistic and antagonistic properties of the bradykinin B2 receptor antagonist, Hoe 140, in isolated blood vessels from different species
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Agonistic and antagonistic pro ...... vessels from different species
@ast
Agonistic and antagonistic pro ...... vessels from different species
@en
type
label
Agonistic and antagonistic pro ...... vessels from different species
@ast
Agonistic and antagonistic pro ...... vessels from different species
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prefLabel
Agonistic and antagonistic pro ...... vessels from different species
@ast
Agonistic and antagonistic pro ...... vessels from different species
@en
P2093
P2860
P1476
Agonistic and antagonistic pro ...... vessels from different species
@en
P2093
P2860
P304
P356
10.1111/J.1476-5381.1994.TB13130.X
P407
P577
1994-06-01T00:00:00Z