H3K36 methylation promotes longevity by enhancing transcriptional fidelity. - Wikidata - awgldk - TriplyDB

H3K36 methylation promotes longevity by enhancing transcriptional fidelity.

H3K36 methylation promotes longevity by enhancing transcriptional fidelity.

http://www.wikidata.org/entity/Q35879041

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Epigenetics and aging Cellular Senescence as the Causal Nexus of Aging Epigenetics of Aging and Alzheimer's Disease: Implications for Pharmacogenomics and Drug Response Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast.Epigenetic regulation of ageing: linking environmental inputs to genomic stability.Life span extension by targeting a link between metabolism and histone acetylation in Drosophila.The Aging Epigenome Selective suppression of antisense transcription by Set2-mediated H3K36 methylation Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity.Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions Stem cells and healthy aging.Sex differences in aging: genomic instability.H3K36 methyltransferases as cancer drug targets: rationale and perspectives for inhibitor development Epigenetic gene regulation by histone demethylases: emerging role in oncogenesis and inflammation.Epigenetic Mechanisms of Longevity and Aging.The Sustained Impact of Model Organisms-in Genetics and Epigenetics.Insulin/insulin-like growth factor-1 signalling (IIS) based regulation of lifespan across species.Interaction between epigenetic and metabolism in aging stem cells.Shaping the cellular landscape with Set2/SETD2 methylation.Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality.The PPARγ-SETD8 axis constitutes an epigenetic, p53-independent checkpoint on p21-mediated cellular senescence H3K36 Methylation Regulates Nutrient Stress Response in Saccharomyces cerevisiae by Enforcing Transcriptional Fidelity.Aggregation of the Whi3 protein, not loss of heterochromatin, causes sterility in old yeast cells.Dissecting Nucleosome Function with a Comprehensive Histone H2A and H2B Mutant Library.Independence between pre-mRNA splicing and DNA methylation in an isogenic minigene resource.Set2 methyltransferase facilitates cell cycle progression by maintaining transcriptional fidelity.Construction of Comprehensive Dosage-Matching Core Histone Mutant Libraries for Saccharomyces cerevisiae.Probe the function of histone lysine 36 methylation using histone H3 lysine 36 to methionine mutant transgene in mammalian cells.Dot1 regulates nucleosome dynamics by its inherent histone chaperone activity in yeast.Epigenetic Mechanisms Impacting Aging: A Focus on Histone Levels and Telomeres.Chromatin immunoprecipitation (ChIP) method for non-model fruit flies (Diptera: Tephritidae) and evidence of histone modifications.Chromatin Architectural Changes during Cellular Senescence and Aging.Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila.Yeast as a tool to identify anti-aging compounds.TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging.Unique patterns of trimethylation of histone H3 lysine 4 are prone to changes during aging in Caenorhabditis elegans somatic cells.Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan Tri-methylation of histone H3 lysine 4 facilitates gene expression in ageing cells The Molecular and Neuropathological Consequences of Genetic Risk for Alzheimer's Dementia H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells

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H3K36 methylation promotes longevity by enhancing transcriptional fidelity.

http://www.wikidata.org/entity/Q35879041

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

H3K36 methylation promotes longevity by enhancing transcriptional fidelity.

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H3K36 methylation promotes longevity by enhancing transcriptional fidelity.

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H3K36 methylation promotes longevity by enhancing transcriptional fidelity.

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H3K36 methylation promotes longevity by enhancing transcriptional fidelity.

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H3K36 methylation promotes longevity by enhancing transcriptional fidelity.

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H3K36 methylation promotes longevity by enhancing transcriptional fidelity.

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Genes & Development

P1476

H3K36 methylation promotes longevity by enhancing transcriptional fidelity.

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Brett Robison

http://www.w3.org/2001/XMLSchema#string

Brian D Gregory

http://www.w3.org/2001/XMLSchema#string

Brian M Wasko

http://www.w3.org/2001/XMLSchema#string

Chong He

http://www.w3.org/2001/XMLSchema#string

Daniel T Carr

http://www.w3.org/2001/XMLSchema#string

Greg Donahue

http://www.w3.org/2001/XMLSchema#string

Jean Dorsey

http://www.w3.org/2001/XMLSchema#string

Jef D Boeke

http://www.w3.org/2001/XMLSchema#string

John Wagner

http://www.w3.org/2001/XMLSchema#string

Jun Yeop Lee

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P2860

Crystal structure of the nucleosome core particle at 2.8 A resolution

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

mTOR is a key modulator of ageing and age-related disease

The transcriptional landscape of the yeast genome defined by RNA sequencing

Histone H4 lysine 16 acetylation regulates cellular lifespan

Histone methylation makes its mark on longevity

The role of chromatin during transcription

Set2 methylation of histone H3 lysine 36 suppresses histone exchange on transcribed genes.

Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription.

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10.1101/GAD.263707.115

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13

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29

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Shelley L. Berger

Brian K Kennedy

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2015-07-01T00:00:00Z

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279988981

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4511212

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