Utilization of C-C chemokine receptor 5 by the envelope glycoproteins of a pathogenic simian immunodeficiency virus, SIVmac239.
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Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infectionHIV type I envelope determinants for use of the CCR2b, CCR3, STRL33, and APJ coreceptorsPersistent infection promotes cross-species transmissibility of mouse hepatitis virusDefining the fitness of HIV-1 isolates with dual/mixed co-receptor usageChanges in human immunodeficiency virus type 1 envelope glycoproteins responsible for the pathogenicity of a multiply passaged simian-human immunodeficiency virus (SHIV-HXBc2)Functional dissection of CCR5 coreceptor function through the use of CD4-independent simian immunodeficiency virus strainsImmunization with a live, attenuated simian immunodeficiency virus vaccine leads to restriction of viral diversity in Rhesus macaques not protected from pathogenic challenge.Tracking members of the simian immunodeficiency virus deltaB670 quasispecies population in vivo at single-cell resolution.Determinants of entry cofactor utilization and tropism in a dualtropic human immunodeficiency virus type 1 primary isolate.Inhibition of simian immunodeficiency virus (SIV) replication by CD8(+) T lymphocytes from macaques immunized with live attenuated SIVUse of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitroThe orphan seven-transmembrane receptor apj supports the entry of primary T-cell-line-tropic and dualtropic human immunodeficiency virus type 1.Simian immunodeficiency virus utilizes human and sooty mangabey but not rhesus macaque STRL33 for efficient entry.Mechanisms for adaptation of simian immunodeficiency virus to replication in alveolar macrophagesSimian immunodeficiency viruses of diverse origin can use CXCR4 as a coreceptor for entry into human cellsCoreceptor-dependent inhibition of the cell fusion activity of simian immunodeficiency virus Env proteins.CD4-independent, CCR5-dependent simian immunodeficiency virus infection and chemotaxis of human cellsUse of inhibitors to evaluate coreceptor usage by simian and simian/human immunodeficiency viruses and human immunodeficiency virus type 2 in primary cells.Species-specific, postentry barriers to primate immunodeficiency virus infection.The level of CD4 expression limits infection of primary rhesus monkey macrophages by a T-tropic simian immunodeficiency virus and macrophagetropic human immunodeficiency viruses.Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants"Resistance" to PSC-RANTES revisited: two mutations in human immunodeficiency virus type 1 HIV-1 SF162 or simian-human immunodeficiency virus SHIV SF162-p3 do not confer resistance.Nef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1.Receptors and entry cofactors for retroviruses include single and multiple transmembrane-spanning proteins as well as newly described glycophosphatidylinositol-anchored and secreted proteins.Rapid progression to simian AIDS can be accompanied by selection of CD4-independent gp120 variants with impaired ability to bind CD4.Human and simian immunodeficiency virus capsid proteins are major viral determinants of early, postentry replication blocks in simian cells.Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development.Cellular localization of the chemokine receptor CCR5. Correlation to cellular targets of HIV-1 infection.CD4-independent use of the CCR5 receptor by sequential primary SIVsm isolatesCCR5 coreceptor utilization involves a highly conserved arginine residue of HIV type 1 gp120.Lineage-specific differences between human and simian immunodeficiency virus regulation of gp120 trimer association and CD4 bindingNatural infection of a homozygous delta24 CCR5 red-capped mangabey with an R2b-tropic simian immunodeficiency virus.Multiple roles for chemokines in the pathogenesis of SIV infectionCD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strainStructure and function of CC-chemokine receptor 5 homologues derived from representative primate species and subspecies of the taxonomic suborders Prosimii and Anthropoidea.A single amino acid change and truncated TM are sufficient for simian immunodeficiency virus to enter cells using CCR5 in a CD4-independent pathway.Binding and susceptibility to postentry restriction factors in monkey cells are specified by distinct regions of the human immunodeficiency virus type 1 capsidHistidine 375 Modulates CD4 Binding in HIV-1 CRF01_AE Envelope Glycoproteins.Lineage-Specific Differences between the gp120 Inner Domain Layer 3 of Human Immunodeficiency Virus and That of Simian Immunodeficiency VirusUse of a gp120 binding assay to dissect the requirements and kinetics of human immunodeficiency virus fusion events
P2860
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P2860
Utilization of C-C chemokine receptor 5 by the envelope glycoproteins of a pathogenic simian immunodeficiency virus, SIVmac239.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Utilization of C-C chemokine r ...... nodeficiency virus, SIVmac239.
@ast
Utilization of C-C chemokine r ...... nodeficiency virus, SIVmac239.
@en
type
label
Utilization of C-C chemokine r ...... nodeficiency virus, SIVmac239.
@ast
Utilization of C-C chemokine r ...... nodeficiency virus, SIVmac239.
@en
prefLabel
Utilization of C-C chemokine r ...... nodeficiency virus, SIVmac239.
@ast
Utilization of C-C chemokine r ...... nodeficiency virus, SIVmac239.
@en
P2093
P2860
P1433
P1476
Utilization of C-C chemokine r ...... nodeficiency virus, SIVmac239.
@en
P2093
J Sodroski
K A Martin
P D Ponath
P2860
P304
P407
P577
1997-03-01T00:00:00Z