A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging.
about
Production of viral vectors using recombinase-mediated cassette exchangeThe adenovirus genome contributes to the structural stability of the virionThe role of chromatin in adenoviral vector functionTargeted chromosomal insertion of large DNA into the human genome by a fiber-modified high-capacity adenovirus-based vector system.Vector and helper genome rearrangements occur during production of helper-dependent adenoviral vectors.GENE THERAPY FOR THE TREATMENT OF PITUITARY TUMORSEffects of stuffer DNA on transgene expression from helper-dependent adenovirus vectors.Generation of adenovirus vectors devoid of all viral genes by recombination between inverted repeatsTransfer of the full-length dystrophin-coding sequence into muscle cells by a dual high-capacity hybrid viral vector with site-specific integration abilityDNA as therapeutics; an update.Bovine adenovirus type 3 virions cannot be rescued in vivo after full-length viral genome transfection in the absence of detectable polypeptide IX.Development of a novel helper-dependent adenovirus-Epstein-Barr virus hybrid system for the stable transformation of mammalian cells.The promise and potential hazards of adenovirus gene therapy.Hyperactive sleeping beauty transposase enables persistent phenotypic correction in mice and a canine model for hemophilia B.Optimization of the helper-dependent adenovirus system for production and potency in vivo.Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector.Transductional targeting of adenovirus vectors for gene therapyDuchenne muscular dystrophy gene therapy in the canine model.Current and future resources for functional metagenomicsAn adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene.A rapid Q-PCR titration protocol for adenovirus and helper-dependent adenovirus vectors that produces biologically relevant results.Viral vectors for vascular gene therapyHelper-Dependent Adenoviral Vectors.Gene therapy with helper-dependent adenoviral vectors: current advances and future perspectives.Adenovirus virion stability and the viral genome: size mattersAdeno-associated virus (AAV) Rep protein enhances the generation of a recombinant mini-adenovirus (Ad) utilizing an Ad/AAV hybrid virusCanine adenovirus vectors: an alternative for adenovirus-mediated gene transfer.Assembly of helper-dependent adenovirus DNA into chromatin promotes efficient gene expression.Integrating adenovirus-adeno-associated virus hybrid vectors devoid of all viral genes.Chromosomal integration pattern of a helper-dependent minimal adenovirus vector with a selectable marker inserted into a 27.4-kilobase genomic stuffer.Variables affecting in vivo performance of high-capacity adenovirus vectors.Minimal cis-acting elements required for adenovirus genome packaging.Genome size and structure determine efficiency of postinternalization steps and gene transfer of capsid-modified adenovirus vectors in a cell-type-specific manner.Improving miRNA Delivery by Optimizing miRNA Expression Cassettes in Diverse Virus Vectors.Activation of adenoviral gene expression by protein IX is not required for efficient virus replication.Helper-dependent adenovirus vectors elicit intact innate but attenuated adaptive host immune responses in vivo.DNA genome size affects the stability of the adenovirus virionHost cell detection of noncoding stuffer DNA contained in helper-dependent adenovirus vectors leads to epigenetic repression of transgene expression.Gene Editing with Helper-Dependent Adenovirus Can Efficiently Introduce Multiple Changes Simultaneously over a Large Genomic Region.Pancreatic transduction by helper-dependent adenoviral vectors via intraductal delivery.
P2860
Q24798297-2E6D8A28-86AB-4536-9BDF-FCAEDB5350A0Q26825101-D61061F9-9010-4D3D-923C-C46BBC380E61Q27004695-E5E7C4A2-DFAB-4573-90F4-9E975B532150Q33366567-EB0A6327-148B-4075-8C52-8881F825F219Q33586303-A4104BAA-F721-493E-AC22-26A9844B6E8AQ33674877-51E624D4-D390-4685-BCAD-BF1C7200AC41Q33818929-CA42350A-00E3-4DD9-B161-9463D5501CE2Q33823132-05459DA5-956E-4906-BEBB-11B88C552A0DQ33834104-005CA1AA-C18E-4673-8133-1A2979ACEE5BQ33836499-71E39182-DEC2-4086-BA98-528A4F3407E4Q33848987-5EB7358D-4F35-42C8-9CF0-8D5D74079264Q34193804-770928A9-9ECF-4E05-8078-E3ED907DB94FQ34219407-84256CE9-9F88-459D-952C-6F5C19227FBDQ34343757-F00ABEF5-0BD1-4C54-8AAF-466C07377345Q34996749-25F294B9-8C60-4DBA-A1E1-9E3E0AAB098AQ35057135-17208547-B8F5-4404-A83D-1D860EFD7034Q35609035-18A19D53-FFA3-471C-84B3-0BAE37204A09Q35641673-E69E9A45-E05B-4AE5-B998-D88BF96F02A9Q35844689-61DDFBC8-71DD-4C4C-9889-5FCD1174E822Q36163092-5BE0E115-64E8-46F8-BC5E-1FB2116B038CQ36920480-5D7B7883-F999-4A3E-B047-CD64717898D0Q37569631-9CA24372-6721-4116-B1F5-B18D2368C98FQ37582126-3B066F10-2FA2-4626-B5E3-A74ACE2E8529Q37945218-6C1148AD-9A26-4DB9-A0EA-777A8AA75FC3Q39502223-D05984E4-57D5-470C-93E1-7042A8463AA9Q39585319-9382CA12-3368-4183-9205-3FE8FA29EC6EQ39588767-56A7AC3C-8B23-4106-8F69-79FB5352EBE5Q39595240-BC3E7FD4-094A-4593-8C55-2007647CAF38Q39596516-010E0962-30E1-464E-AE36-B4D754BCA468Q39604468-318DA36A-3EB9-4C7C-81C0-CA620B9E4629Q39682415-7318E2DE-2213-4927-B50F-D811E5A8A551Q39748690-A0886810-C57D-46EB-BC00-EE5F61AE970AQ39960246-910C2BA8-45A7-432C-890B-D0BE10DC45FEQ40121209-D095B5C3-B2F1-41BF-B757-EE4929CD4749Q40815010-6135DBB8-DA71-45AD-A439-78A0AE6F6075Q40883683-085ED1A1-BE3C-444C-ADF3-A32B30EBBC88Q41831763-34CCECF9-B087-466B-A5D6-326D1E7D6493Q42002320-DA3714E7-B624-4799-A2B7-3C345123D3A8Q42149489-F8D263B9-2140-44BF-9A2A-5D469EFDB9C4Q42204796-3C9CE8A4-B0C7-49E4-BDF0-630A351409CB
P2860
A helper-dependent system for adenovirus vector production helps define a lower limit for efficient DNA packaging.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
A helper-dependent system for ...... t for efficient DNA packaging.
@ast
A helper-dependent system for ...... t for efficient DNA packaging.
@en
type
label
A helper-dependent system for ...... t for efficient DNA packaging.
@ast
A helper-dependent system for ...... t for efficient DNA packaging.
@en
prefLabel
A helper-dependent system for ...... t for efficient DNA packaging.
@ast
A helper-dependent system for ...... t for efficient DNA packaging.
@en
P2860
P1433
P1476
A helper-dependent system for ...... it for efficient DNA packaging
@en
P2093
P2860
P304
P407
P577
1997-04-01T00:00:00Z