Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other.
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Trafficking Dynamics of PCSK9-Induced LDLR Degradation: Focus on Human PCSK9 Mutations and C-Terminal DomainPhysiological and therapeutic regulation of PCSK9 activity in cardiovascular disease.PCSK9 deficiency unmasks a sex- and tissue-specific subcellular distribution of the LDL and VLDL receptors in mice.Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9.The enigmatic role of sortilin in lipoprotein metabolism.Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor Degradation.The Proprotein Convertases in Hypercholesterolemia and Cardiovascular Diseases: Emphasis on Proprotein Convertase Subtilisin/Kexin 9.The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation: A NOVEL MECHANISM CAUSING FAMILIAL HYPERCHOLESTEROLEMIA.Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism.Proteolytic cleavage of antigen extends the durability of an anti-PCSK9 monoclonal antibody.The PCSK9 revolution and the potential of PCSK9-based therapies to reduce LDL-cholesterol.(Pro)renin Receptor and LDL Clearance: An Old Player Joins A New Game.An Unbiased Mass Spectrometry Approach Identifies Glypican-3 as an Interactor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR) in Hepatocellular Carcinoma Cells.Development of a Cell-Based Assay to Assess Binding of the proNGF Prodomain to Sortilin.Sortilin 1 Modulates Hepatic Cholesterol Lipotoxicity in Mice via Functional Interaction with Liver Carboxylesterase 1.APP, APLP2 and LRP1 interact with PCSK9 but are not required for PCSK9-mediated degradation of the LDLR in vivo.Sortilin 1 knockout alters basal adipose glucose metabolism but not diet-induced obesity in mice.The cargo receptor SURF4 promotes the efficient cellular secretion of PCSK9
P2860
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P2860
Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other.
description
2015 nî lūn-bûn
@nan
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
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2015年论文
@zh-cn
name
Amyloid Precursor-like Protein ...... but Interact with Each Other.
@ast
Amyloid Precursor-like Protein ...... but Interact with Each Other.
@en
type
label
Amyloid Precursor-like Protein ...... but Interact with Each Other.
@ast
Amyloid Precursor-like Protein ...... but Interact with Each Other.
@en
prefLabel
Amyloid Precursor-like Protein ...... but Interact with Each Other.
@ast
Amyloid Precursor-like Protein ...... but Interact with Each Other.
@en
P2093
P2860
P50
P356
P1476
Amyloid Precursor-like Protein ...... but Interact with Each Other.
@en
P2093
Ann Chamberland
Anna Roubtsova
Chutikarn Butkinaree
Gaétan Mayer
Jadwiga Marcinkiewicz
Josée Hamelin
Marie-Claude Asselin
Maryssa Canuel
Rachid Essalmani
Sangram S Sisodia
P2860
P304
18609-18620
P356
10.1074/JBC.M115.647180
P407
P577
2015-06-17T00:00:00Z