All-trans retinoic acid synergizes with topotecan to suppress AML cells via promoting RARα-mediated DNA damage

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Comet assay: an essential tool in toxicological research.PLGA-PEG-RA-based polymeric micelles for tumor targeted delivery of irinotecan.

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All-trans retinoic acid synergizes with topotecan to suppress AML cells via promoting RARα-mediated DNA damage

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2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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2016年学术文章

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All-trans retinoic acid synerg ...... oting RARα-mediated DNA damage

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All-trans retinoic acid synerg ...... oting RARα-mediated DNA damage

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All-trans retinoic acid synerg ...... oting RARα-mediated DNA damage

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All-trans retinoic acid synerg ...... oting RARα-mediated DNA damage

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All-trans retinoic acid synerg ...... oting RARα-mediated DNA damage

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All-trans retinoic acid synerg ...... oting RARα-mediated DNA damage

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All-trans retinoic acid synerg ...... oting RARα-mediated DNA damage

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P2093

Bo Yang

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Guanqun Li

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Hao Yan

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JinJin Shao

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Lin Li

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Min Chen

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Peihua Luo

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Qiaojun He

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Xueming Peng

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Zhifei Xu

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P2860

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

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Arsenic trioxide induces oxidative stress, DNA damage, and mitochondrial pathway of apoptosis in human leukemia (HL-60) cells.

Combination of cladribine plus topotecan for recurrent or refractory pediatric acute myeloid leukemia.

ERBB3 knockdown induces cell cycle arrest and activation of Bak and Bax-dependent apoptosis in colon cancer cells.

Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells.

Topoisomerase I inhibitors, shikonin and topotecan, inhibit growth and induce apoptosis of glioma cells and glioma stem cells.

Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis.

Topotecan synergizes with CHEK1 (CHK1) inhibitor to induce apoptosis in ovarian cancer cells.

Chk1 in the DNA damage response: conserved roles from yeasts to mammals.

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s12885-015-2010-6

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scholarly article

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10.1186/S12885-015-2010-6

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2016-01-05T00:00:00Z

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290454601

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DNA damage

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4700651

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All-trans retinoic acid synergizes with topotecan to suppress AML cells via promoting RARα-mediated DNA damage

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P2860

P2860

All-trans retinoic acid synergizes with topotecan to suppress AML cells via promoting RARα-mediated DNA damage

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type

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P1433

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