Strategies and Approaches of Targeting STAT3 for Cancer Treatment.
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Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitorsB1, a novel HDAC inhibitor, induces apoptosis through the regulation of STAT3 and NF-κB.Identification of New Shikonin Derivatives as Antitumor Agents Targeting STAT3 SH2 Domain.Alteration of SHP-1/p-STAT3 Signaling: A Potential Target for Anticancer Therapy.CPA-7 influences immune profile and elicits anti-prostate cancer effects by inhibiting activated STAT3.Tyrosine kinase c-Abl regulates the survival of plasma cellsAn inhibitor of cholesterol absorption displays anti-myeloma activity by targeting the JAK2-STAT3 signaling pathwayMolecular interplay of pro-inflammatory transcription factors and non-coding RNAs in esophageal squamous cell carcinoma.New sulfurated derivatives of cinnamic acids and rosmaricine as inhibitors of STAT3 and NF-κB transcription factors.MicroRNA-125a-5p plays a role as a tumor suppressor in lung carcinoma cells by directly targeting STAT3.Artemisinin as an anticancer drug: Recent advances in target profiling and mechanisms of action.15α-methoxypuupehenol Induces Antitumor Effects In Vitro and In Vivo against Human Glioblastoma and Breast Cancer Models.Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models.Integration of phytochemicals and phytotherapy into cancer precision medicine.Signal transducer and activator of transcription 3 as a therapeutic target for cancer and the tumor microenvironment.STAT3 activation in infection and infection-associated cancer.Evaluation of quantitative assays for the identification of direct signal transducer and activator of transcription 3 (STAT3) inhibitors.Multifunctional Effects of a Small-Molecule STAT3 Inhibitor on NASH and Hepatocellular Carcinoma in Mice.U/G SNP rs111904020 in 3'UTR of STAT3 regulated by miR-214 promotes hepatocellular carcinoma development in Chinese population.CAMK2γ in intestinal epithelial cells modulates colitis-associated colorectal carcinogenesis via enhancing STAT3 activation.Benefits of Multifaceted Chemopreventives in the Suppression of the Oral Squamous Cell Carcinoma (OSCC) Tumorigenic Phenotype.Sorafenib analogue SC-60 induces apoptosis through the SHP-1/STAT3 pathway and enhances docetaxel cytotoxicity in triple-negative breast cancer cells.The tyrosine kinase inhibitor nintedanib activates SHP-1 and induces apoptosis in triple-negative breast cancer cells.IL-27 mediates HLA class I up-regulation, which can be inhibited by the IL-6 pathway, in HLA-deficient Small Cell Lung Cancer cells.Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis.Metformin inhibits esophageal squamous cell carcinoma-induced angiogenesis by suppressing JAK/STAT3 signaling pathway.MMPP Attenuates Non-Small Cell Lung Cancer Growth by Inhibiting the STAT3 DNA-Binding Activity via Direct Binding to the STAT3 DNA-Binding Domain.Naphthoquinones: A continuing source for discovery of therapeutic antineoplastic agents.Combination curcumin and (-)-epigallocatechin-3-gallate inhibits colorectal carcinoma microenvironment-induced angiogenesis by JAK/STAT3/IL-8 pathway.Caveolin-1-mediated STAT3 activation determines electrotaxis of human lung cancer cells.Inorganic Kernel-Reconstituted Lipoprotein Biomimetic Nanovehicles Enable Efficient Targeting "Trojan Horse" Delivery of STAT3-Decoy Oligonucleotide for Overcoming TRAIL Resistance.Nitidine chloride acts as an apoptosis inducer in human oral cancer cells and a nude mouse xenograft model via inhibition of STAT3.Targeting Oncogenic Transcription Factors: Therapeutic Implications of Endogenous STAT Inhibitors.MIG-6 negatively regulates STAT3 phosphorylation in uterine epithelial cells.From Pathology to Precision Medicine in Anaplastic Large Cell Lymphoma Expressing Anaplastic Lymphoma Kinase (ALK+ ALCL).Micellar nano-carriers for the delivery of STAT3 dimerization inhibitors to melanoma.Visualization and quantification of dynamic STAT3 homodimerization in living cells using homoFluoppi.IRF4 Mediates the Oncogenic Effects of STAT3 in Anaplastic Large Cell Lymphomas.ALDH1A2 suppresses epithelial ovarian cancer cell proliferation and migration by downregulating STAT3.The role of STAT3 in leading the crosstalk between human cancers and the immune system.
P2860
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P2860
Strategies and Approaches of Targeting STAT3 for Cancer Treatment.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Strategies and Approaches of Targeting STAT3 for Cancer Treatment.
@ast
Strategies and Approaches of Targeting STAT3 for Cancer Treatment.
@en
type
label
Strategies and Approaches of Targeting STAT3 for Cancer Treatment.
@ast
Strategies and Approaches of Targeting STAT3 for Cancer Treatment.
@en
prefLabel
Strategies and Approaches of Targeting STAT3 for Cancer Treatment.
@ast
Strategies and Approaches of Targeting STAT3 for Cancer Treatment.
@en
P2093
P1433
P1476
Strategies and Approaches of Targeting STAT3 for Cancer Treatment
@en
P2093
Christopher J Matheson
Philip Reigan
Steffanie L Furtek
P304
P356
10.1021/ACSCHEMBIO.5B00945
P577
2016-01-15T00:00:00Z