about
PharmGKB summary: very important pharmacogene information for cytochrome P-450, family 2, subfamily A, polypeptide 6ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification.Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse modelGap junctions in olfactory neurons modulate olfactory sensitivity.Mechanisms of olfactory toxicity of the herbicide 2,6-dichlorobenzonitrile: essential roles of CYP2A5 and target-tissue metabolic activation.Hepatic and renal cytochrome p450 gene regulation during citrobacter rodentium infection in wild-type and toll-like receptor 4 mutant mice.Identification of cytochrome P450 enzymes critical for lung tumorigenesis by the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): insights from a novel Cyp2abfgs-null mouseEthanol induction of CYP2A5: permissive role for CYP2E1A novel defensive mechanism against acetaminophen toxicity in the mouse lateral nasal gland: role of CYP2A5-mediated regulation of testosterone homeostasis and salivary androgen-binding protein expression.Signatures of rapid evolution in urban and rural transcriptomes of white-footed mice (Peromyscus leucopus) in the New York metropolitan area.Modulation of cytochrome P450 2A5 activity by lipopolysaccharide: low-dose effects and non-monotonic dose-response relationship.Absence of cytochrome P450 2A5 enhances alcohol-induced liver injury in mice.Respective roles of CYP2A5 and CYP2F2 in the bioactivation of 3-methylindole in mouse olfactory mucosa and lung: studies using Cyp2a5-null and Cyp2f2-null mouse models.Generation and characterization of a CYP2A13/2B6/2F1-transgenic mouse modelInterstrain differences in the expression and activity of Cyp2a5 in the mouse liver.Nicotinic alpha 7 receptor expression and modulation of the lung epithelial response to lipopolysaccharide.Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathwayThe role of CYP2A5 in liver injury and fibrosis: chemical-specific difference.Generation and characterization of a novel Cyp2a(4/5)bgs-null mouse modelEmerging evidence for the interrelationship of xenobiotic exposure and circadian rhythms: a review.In vivo modulation of the behavioral effects of nicotine by the coumarins xanthotoxin, bergapten, and umbelliferoneNicotine enhances ethanol-induced fat accumulation and collagen deposition but not inflammation in mouse liver.Gene expression and immunochemical localization of major cytochrome P450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa.Cortisol-treated zebrafish embryos develop into pro-inflammatory adults with aberrant immune gene regulation.CYP2A6 polymorphisms and risk for tobacco-related cancers.Essential role of the cytochrome P450 enzyme CYP2A5 in olfactory mucosal toxicity of naphthalene.Selective effects of a therapeutic protein targeting tumor necrosis factor-alpha on cytochrome P450 regulation during infectious colitis: Implications for disease-dependent drug-drug interactions.Psychophysiological stress: a significant parameter in drug pharmacokinetics.Alcoholic Liver Disease: from CYP2E1 to CYP2A5.Nicotine metabolism and urinary elimination in mouse: in vitro and in vivo.Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARα-FGF21 axis.CYP2A6 is associated with obesity: studies in human samples and a high fat diet mouse model.Cytochrome P450s And Alcoholic Liver Disease.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Regulation of the cytochrome P450 2A genes.
@ast
Regulation of the cytochrome P450 2A genes.
@en
type
label
Regulation of the cytochrome P450 2A genes.
@ast
Regulation of the cytochrome P450 2A genes.
@en
prefLabel
Regulation of the cytochrome P450 2A genes.
@ast
Regulation of the cytochrome P450 2A genes.
@en
P1476
Regulation of the cytochrome P450 2A genes.
@en
P2093
P304
P356
10.1016/J.TAAP.2003.11.029
P577
2004-09-01T00:00:00Z